NR 565 Pharmacology Week 1 LATEST VERSION WITH COMPLETE QUESTIONS AND CORRECT DETAILED ANSWERS VERIFIED 100% GRADED A+

NR 565 Pharmacology Week 1 LATEST VERSION WITH
COMPLETE QUESTIONS AND CORRECT DETAILED ANSWERS
\VERIFIED 100% GRADED A+



Phamacodynamics: 3 mechanisms of action


Receptor
Enzyme
Non-selective interactions (i.e. chemo)


Types of drug therapy (7)


Acute
Maintenance (HTN/bc)
Supplemental (insulin)
Palliative
Supportive (IV fluid)
Prophylactic
Empirical (broad-spectrum abx)


Idiosyncratic Effect


Unexpected response to medication


Tolerance


Declining response to a drug

,Dependence


Physiological/psychological need for a drug; needs drug for normal
function

Addiction


Compulsive use of a drug despite negative/dangerous effects


Drug interactions: drug-drug


When 2 drugs compete for metabolizing enzymes


Drug interactions: food-drug


Grapefruit juice or leafy greens


Drug interactions: additive


1+1 = 2; both provide intended effect


Drug interactions: antagonistic


1+1 = <2; less than desired effect of one or both drugs


Drug interactions: synergistic


1+1 = >2; sum total effect is greater than if given alone (i.e. lisinopril + HCTZ)

, Drug interactions: incompatibility


1+1 does not equal 2; two IV drugs given together causing
decomposition of one or both drugs


8 rights of medication administration


Patient
Medicati
on Dose
Route
Time
Reason
Respons
e
Documentation

Adverse reactions: pharmacologic


Extension of a drug's normal effect


Adverse reactions: Allergic/hypersensitivity


Exaggerated immune response (i.e. mild itching to anaphylaxis)


Adverse reactions: idiosyncratic


Peculiar to the patient