Medical-Surgical Nursing MCQ Study Guide & Practice Question Bank

Harrison's Principles of Internal Medicine
(Vol.1 & Vol.2)
22nd Edition
• Author(s)Joseph Loscalzo; Anthony S.
Fauci; Dennis L. Kasper; Stephen Hauser;
Dan Longo; J. Larry Jameson
Test Bank




Covered

PART 1: Foundations of Clinical Medicine

PART 2: Cardinal Symptoms & Clinical Presentations

PART 3: Clinical Pharmacology

PART 4: Oncology & Hematology

PART 5: Infectious Diseases

PART 6: Cardiovascular Disorders

PART 7: Respiratory Disorders

PART 8: Critical Care Medicine

PART 9: Kidney & Urinary Tract Disorders

PART 10: Gastrointestinal & Hepatobiliary Disorders

,PART 11: Immune-Mediated & Rheumatologic Disorders

PART 12: Endocrinology & Metabolism

PART 13: Neurologic & Psychiatric Disorders

PART 14: Toxicology & Environmental Injury

PART 15: Environmental & Occupational Medicine

PART 16: Genetics, Precision & Systems Medicine

PART 17–20: Special & Emerging Topics




Harrison’s Principles of Internal Medicine (22nd ed.)
Chapters 1–13 (Foundations of Clinical Medicine)
Total: 20 MCQs


1.
Which principle best defines the practice of medicine as
described in Harrison’s?
A. Application of standardized protocols to all patients
B. Integration of scientific evidence with individual patient
values
C. Reliance on diagnostic testing over clinical judgment
D. Prioritization of cost containment over patient-centered care
Correct Answer: B
Rationale: Harrison emphasizes medicine as a balance of

,scientific knowledge, clinical expertise, and patient values
rather than rigid protocol application.
Citation: Harrison’s Principles of Internal Medicine, 22nd ed.,
Chapter 1 – The Practice of Medicine


2.
From a nursing perspective, which factor most strongly
promotes good health at the population level?
A. Increased specialty care access
B. Genetic screening programs
C. Social and environmental determinants
D. Advanced diagnostic technologies
Correct Answer: C
Rationale: Harrison highlights social, economic, and
environmental factors as primary drivers of population health
outcomes.
Citation: Harrison’s Principles of Internal Medicine, 22nd ed.,
Chapter 2 – Promoting Good Health


3.
Which concern most commonly underlies vaccine hesitancy in
high-income countries?
A. Vaccine supply shortages
B. Religious prohibitions

, C. Fear of adverse effects and mistrust
D. Lack of provider recommendations
Correct Answer: C
Rationale: Harrison identifies fear of harm and mistrust in
institutions as central contributors to vaccine opposition.
Citation: Harrison’s Principles of Internal Medicine, 22nd ed.,
Chapter 3 – Vaccine Opposition and Hesitancy


4.
Which nursing action best supports shared decision-making in
clinical care?
A. Presenting only the recommended treatment option
B. Deferring decisions entirely to the physician
C. Explaining risks and benefits in understandable terms
D. Avoiding discussion of uncertain outcomes
Correct Answer: C
Rationale: Shared decision-making requires transparent
communication tailored to patient comprehension.
Citation: Harrison’s Principles of Internal Medicine, 22nd ed.,
Chapter 4 – Decision-Making in Clinical Medicine


5.
Precision medicine primarily aims to: