Medical-Surgical Nursing Fast-Revision MCQ Study Guide & Practice Test Bank

Harrison's Principles of Internal Medicine
(Vol.1 & Vol.2)
22nd Edition
• Author(s)Joseph Loscalzo; Anthony S.
Fauci; Dennis L. Kasper; Stephen Hauser;
Dan Longo; J. Larry Jameson
Test Bank




Covered

PART 1: Foundations of Clinical Medicine

PART 2: Cardinal Symptoms & Clinical Presentations

PART 3: Clinical Pharmacology

PART 4: Oncology & Hematology

PART 5: Infectious Diseases

PART 6: Cardiovascular Disorders

PART 7: Respiratory Disorders

PART 8: Critical Care Medicine

PART 9: Kidney & Urinary Tract Disorders

PART 10: Gastrointestinal & Hepatobiliary Disorders

,PART 11: Immune-Mediated & Rheumatologic Disorders

PART 12: Endocrinology & Metabolism

PART 13: Neurologic & Psychiatric Disorders

PART 14: Toxicology & Environmental Injury

PART 15: Environmental & Occupational Medicine

PART 16: Genetics, Precision & Systems Medicine

PART 17–20: Special & Emerging Topics




1. (Chapter 1 — The Practice of Medicine) A 68-year-old
patient asks why the physician orders molecular tests in
addition to a physical exam. Which statement best explains
the current role of molecular testing in practice?
A. Molecular tests replace the need for a focused history
and exam.
B. Molecular tests primarily confirm diagnoses that are
already certain from exam alone.
C. Molecular tests complement clinical evaluation by
clarifying diagnosis and guiding targeted therapy.
D. Molecular testing is used only for research and not for
routine clinical decisions.
Answer: C
Rationale: Modern practice integrates molecular data with
history/exam to refine diagnosis and target treatment; it is
complementary, not a replacement.

,2. (Chapter 2 — Promoting Good Health) Which preventive
action is the highest priority for reducing population
disease burden?
A. Increasing tertiary care capacity.
B. Implementing effective primary prevention strategies.
C. Expanding palliative care services.
D. Mandating hospital-acquired infection reporting.
Answer: B
Rationale: Primary prevention (reducing incidence) yields
the greatest population health benefit when feasible.


3. (Chapter 3 — Vaccine Opposition and Hesitancy) A nurse
encounters a hesitant parent. According to the chapter,
which approach is most likely to increase vaccine uptake?
A. Presenting long lists of statistical data.
B. Giving an ambiguous recommendation and leaving the
choice to the parent.
C. Making a strong, clear recommendation as a trusted
health professional.
D. Refusing care until vaccination is accepted.
Answer: C
Rationale: An unambiguous, strong recommendation from
a trusted clinician is a key determinant in persuading
vaccine-hesitant patients.

, 4. (Chapter 3 — Vaccine Opposition and Hesitancy) Which
factor is described as a common determinant of vaccine
hesitancy?
A. Universal access to care.
B. High confidence in public health institutions.
C. Concerns about vaccine safety and mistrust of
authorities.
D. Mandatory vaccination laws only.
Answer: C
Rationale: Hesitancy is multifactorial; safety concerns and
mistrust are central drivers.


5. (Chapter 4 — Decision-Making in Clinical Medicine) When
ordering diagnostic tests, the nurse should prioritize:
A. Tests that are maximal in number to avoid missed
diagnoses.
B. Tests guided by pretest probability and how results will
change management.
C. The cheapest available tests regardless of accuracy.
D. Tests requested by the patient even if low yield.
Answer: B
Rationale: Rational test use depends on pretest probability
and whether results will affect clinical decisions.


6. (Chapter 4 — Decision-Making in Clinical Medicine) Which
cognitive strategy reduces diagnostic error by countering