Answers Correct
1. What is the effect of oxidized low-density lipoproteins (LDLs) in atherosclero-
sis?
A) LDLs cause smooth muscle proliferation
B) LDLs cause regression of atherosclerotic plaques
C) LDLs increase levels of inflammatory cytokines
D) LDLs direct microphages to the site in the endothelium: Ans: A- LDLs cause smooth
muscle proliferation
2. Which inflammatory cytokines are released when endothelial cells are in-
jured?
A) granulocyte-macrophage colony-stimulating factor (GM-CSF)
B) interferon-beta (IFN-β), interleukin 6 (IL-6), and granulocyte colony-stimulat-
ing factor (G-CSF)
C) tumor necrosis factor-alpha (TNF-α), interferon-gamma (IFN-γ), and inter-
leukin 1 (IL-1)
D) interferon-alpha (IFN-α), interleukin 12 (IL-12), and macrophage colony-stim-
ulating factor (M-CSF): Ans: C- tumor necrosis factor-alpha (TNF-α), interferon-gamma (IFN-γ), and inter-
leukin 1 (IL-1)
3. When endothelia cells are injured, which alteration contributes to atheroscle-
rosis?
A) toxic oxygen radicals that oxidize low-density lipoproteins (LDLs) are re-
leased
B) cells are unable to make the normal amount of vasodilation cytokines
C) cells produce an increased amount of anti-thrombotic cytokines
D) cells develop hypersensitivity to homocysteine and lipids: Ans: B- cells are unable to
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, make the normal amount of vasodilation cytokines
4. Which factor is responsible for hypertrophy of the myocardium associated
with hypertension?
A) increased norepinephrine
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