Harrison's Principles of Internal Medicine
(Vol.1 & Vol.2)
22nd Edition
• Author(s)Joseph Loscalzo; Anthony S.
Fauci; Dennis L. Kasper; Stephen Hauser;
Dan Longo; J. Larry Jameson
Test Bank
Covered
PART 1: Foundations of Clinical Medicine
PART 2: Cardinal Symptoms & Clinical Presentations
PART 3: Clinical Pharmacology
PART 4: Oncology & Hematology
PART 5: Infectious Diseases
PART 6: Cardiovascular Disorders
PART 7: Respiratory Disorders
PART 8: Critical Care Medicine
PART 9: Kidney & Urinary Tract Disorders
PART 10: Gastrointestinal & Hepatobiliary Disorders
,PART 11: Immune-Mediated & Rheumatologic Disorders
PART 12: Endocrinology & Metabolism
PART 13: Neurologic & Psychiatric Disorders
PART 14: Toxicology & Environmental Injury
PART 15: Environmental & Occupational Medicine
PART 16: Genetics, Precision & Systems Medicine
PART 17–20: Special & Emerging Topics
Harrison’s Principles of Internal Medicine, 22nd ed.
1. Which principle best defines the modern practice of
medicine as described in Harrison’s?
A. Reliance on technological diagnostics over clinical judgment
B. Integration of scientific evidence with compassionate patient
care
C. Standardized protocols applied uniformly to all patients
D. Emphasis on curative treatment rather than prevention
Correct Answer: B
Rationale: Harrison’s emphasizes medicine as both a science
and a humanistic practice integrating evidence-based
knowledge with patient-centered care.
Citation: Harrison’s Principles of Internal Medicine, 22nd ed.,
Chapter 1 – The Practice of Medicine
,2. Which factor has the greatest impact on population health
outcomes?
A. Access to tertiary care centers
B. Genetic predisposition
C. Social and behavioral determinants
D. Advanced pharmaceutical therapies
Correct Answer: C
Rationale: Harrison’s identifies social, economic, and behavioral
factors as major drivers of population health outcomes.
Citation: Harrison’s, 22nd ed., Chapter 2 – Promoting Good
Health
3. Vaccine hesitancy is most commonly driven by which
concern?
A. Cost of immunization
B. Distrust in health systems and misinformation
C. Religious contraindications
D. Lack of vaccine availability
Correct Answer: B
Rationale: Harrison’s highlights misinformation and lack of trust
as primary contributors to vaccine opposition.
Citation: Harrison’s, 22nd ed., Chapter 3 – Vaccine Opposition
and Hesitancy
, 4. Clinical decision-making under uncertainty most relies on
which approach?
A. Intuition-based judgment
B. Algorithmic diagnosis alone
C. Probabilistic reasoning and risk assessment
D. Patient preference only
Correct Answer: C
Rationale: Harrison’s emphasizes probabilistic reasoning as
central to diagnostic and therapeutic decision-making.
Citation: Harrison’s, 22nd ed., Chapter 4 – Decision-Making in
Clinical Medicine
5. Precision medicine primarily aims to:
A. Replace population-based guidelines
B. Tailor care based on individual variability
C. Focus exclusively on genomic data
D. Eliminate clinical judgment
Correct Answer: B
Rationale: Precision medicine integrates genetic,
environmental, and lifestyle factors to individualize care.
Citation: Harrison’s, 22nd ed., Chapter 5 – Precision Medicine
and Clinical Care
6. An effective screening program must demonstrate:
(Vol.1 & Vol.2)
22nd Edition
• Author(s)Joseph Loscalzo; Anthony S.
Fauci; Dennis L. Kasper; Stephen Hauser;
Dan Longo; J. Larry Jameson
Test Bank
Covered
PART 1: Foundations of Clinical Medicine
PART 2: Cardinal Symptoms & Clinical Presentations
PART 3: Clinical Pharmacology
PART 4: Oncology & Hematology
PART 5: Infectious Diseases
PART 6: Cardiovascular Disorders
PART 7: Respiratory Disorders
PART 8: Critical Care Medicine
PART 9: Kidney & Urinary Tract Disorders
PART 10: Gastrointestinal & Hepatobiliary Disorders
,PART 11: Immune-Mediated & Rheumatologic Disorders
PART 12: Endocrinology & Metabolism
PART 13: Neurologic & Psychiatric Disorders
PART 14: Toxicology & Environmental Injury
PART 15: Environmental & Occupational Medicine
PART 16: Genetics, Precision & Systems Medicine
PART 17–20: Special & Emerging Topics
Harrison’s Principles of Internal Medicine, 22nd ed.
1. Which principle best defines the modern practice of
medicine as described in Harrison’s?
A. Reliance on technological diagnostics over clinical judgment
B. Integration of scientific evidence with compassionate patient
care
C. Standardized protocols applied uniformly to all patients
D. Emphasis on curative treatment rather than prevention
Correct Answer: B
Rationale: Harrison’s emphasizes medicine as both a science
and a humanistic practice integrating evidence-based
knowledge with patient-centered care.
Citation: Harrison’s Principles of Internal Medicine, 22nd ed.,
Chapter 1 – The Practice of Medicine
,2. Which factor has the greatest impact on population health
outcomes?
A. Access to tertiary care centers
B. Genetic predisposition
C. Social and behavioral determinants
D. Advanced pharmaceutical therapies
Correct Answer: C
Rationale: Harrison’s identifies social, economic, and behavioral
factors as major drivers of population health outcomes.
Citation: Harrison’s, 22nd ed., Chapter 2 – Promoting Good
Health
3. Vaccine hesitancy is most commonly driven by which
concern?
A. Cost of immunization
B. Distrust in health systems and misinformation
C. Religious contraindications
D. Lack of vaccine availability
Correct Answer: B
Rationale: Harrison’s highlights misinformation and lack of trust
as primary contributors to vaccine opposition.
Citation: Harrison’s, 22nd ed., Chapter 3 – Vaccine Opposition
and Hesitancy
, 4. Clinical decision-making under uncertainty most relies on
which approach?
A. Intuition-based judgment
B. Algorithmic diagnosis alone
C. Probabilistic reasoning and risk assessment
D. Patient preference only
Correct Answer: C
Rationale: Harrison’s emphasizes probabilistic reasoning as
central to diagnostic and therapeutic decision-making.
Citation: Harrison’s, 22nd ed., Chapter 4 – Decision-Making in
Clinical Medicine
5. Precision medicine primarily aims to:
A. Replace population-based guidelines
B. Tailor care based on individual variability
C. Focus exclusively on genomic data
D. Eliminate clinical judgment
Correct Answer: B
Rationale: Precision medicine integrates genetic,
environmental, and lifestyle factors to individualize care.
Citation: Harrison’s, 22nd ed., Chapter 5 – Precision Medicine
and Clinical Care
6. An effective screening program must demonstrate:
