Harrison's Principles of Internal Medicine
(Vol.1 & Vol.2)
22nd Edition
• Author(s)Joseph Loscalzo; Anthony S.
Fauci; Dennis L. Kasper; Stephen Hauser;
Dan Longo; J. Larry Jameson
Test Bank
Covered
PART 1: Foundations of Clinical Medicine
PART 2: Cardinal Symptoms & Clinical Presentations
PART 3: Clinical Pharmacology
PART 4: Oncology & Hematology
PART 5: Infectious Diseases
PART 6: Cardiovascular Disorders
PART 7: Respiratory Disorders
PART 8: Critical Care Medicine
PART 9: Kidney & Urinary Tract Disorders
PART 10: Gastrointestinal & Hepatobiliary Disorders
,PART 11: Immune-Mediated & Rheumatologic Disorders
PART 12: Endocrinology & Metabolism
PART 13: Neurologic & Psychiatric Disorders
PART 14: Toxicology & Environmental Injury
PART 15: Environmental & Occupational Medicine
PART 16: Genetics, Precision & Systems Medicine
PART 17–20: Special & Emerging Topics
1. The Practice of Medicine (Ch. 1)
1. Which principle best defines evidence-based medical
practice as described in Harrison’s?
A. Reliance on expert opinion
B. Application of randomized trials only
C. Integration of clinical expertise, patient values, and best
evidence
D. Use of guidelines without individualization
Correct Answer: C
Rationale: Evidence-based medicine integrates research
evidence with clinical judgment and patient preferences.
Citation: Harrison’s Principles of Internal Medicine, 22nd ed.,
Ch. 1
2. Promoting Good Health (Ch. 2)
,2. Which intervention provides the greatest population-level
health benefit?
A. Advanced imaging
B. Lifestyle modification
C. Genetic testing
D. Surgical intervention
Correct Answer: B
Rationale: Health promotion through behavior modification
yields the largest reduction in morbidity and mortality.
Citation: Harrison’s Principles of Internal Medicine, 22nd ed.,
Ch. 2
3. Vaccine Opposition and Hesitancy (Ch. 3)
3. What nursing approach is most effective when addressing
vaccine hesitancy?
A. Presenting statistical risk alone
B. Dismissing patient concerns
C. Using empathetic, respectful dialogue
D. Mandating vaccination without discussion
Correct Answer: C
Rationale: Trust-building communication addressing concerns
respectfully improves vaccine acceptance.
Citation: Harrison’s Principles of Internal Medicine, 22nd ed.,
Ch. 3
, 4. Decision-Making in Clinical Medicine (Ch. 4)
4. Shared decision-making requires which key element?
A. Physician-directed choices
B. Exclusion of patient preferences
C. Clear communication of risks and benefits
D. Avoidance of uncertainty discussion
Correct Answer: C
Rationale: Patients must understand options, risks, and benefits
to participate meaningfully.
Citation: Harrison’s Principles of Internal Medicine, 22nd ed.,
Ch. 4
5. Precision Medicine and Clinical Care (Ch. 5)
5. Precision medicine primarily aims to:
A. Replace clinical assessment
B. Individualize care using genetic and molecular data
C. Standardize treatment protocols
D. Reduce diagnostic testing
Correct Answer: B
Rationale: Precision medicine tailors prevention and treatment
to individual biological differences.
Citation: Harrison’s Principles of Internal Medicine, 22nd ed.,
Ch. 5
(Vol.1 & Vol.2)
22nd Edition
• Author(s)Joseph Loscalzo; Anthony S.
Fauci; Dennis L. Kasper; Stephen Hauser;
Dan Longo; J. Larry Jameson
Test Bank
Covered
PART 1: Foundations of Clinical Medicine
PART 2: Cardinal Symptoms & Clinical Presentations
PART 3: Clinical Pharmacology
PART 4: Oncology & Hematology
PART 5: Infectious Diseases
PART 6: Cardiovascular Disorders
PART 7: Respiratory Disorders
PART 8: Critical Care Medicine
PART 9: Kidney & Urinary Tract Disorders
PART 10: Gastrointestinal & Hepatobiliary Disorders
,PART 11: Immune-Mediated & Rheumatologic Disorders
PART 12: Endocrinology & Metabolism
PART 13: Neurologic & Psychiatric Disorders
PART 14: Toxicology & Environmental Injury
PART 15: Environmental & Occupational Medicine
PART 16: Genetics, Precision & Systems Medicine
PART 17–20: Special & Emerging Topics
1. The Practice of Medicine (Ch. 1)
1. Which principle best defines evidence-based medical
practice as described in Harrison’s?
A. Reliance on expert opinion
B. Application of randomized trials only
C. Integration of clinical expertise, patient values, and best
evidence
D. Use of guidelines without individualization
Correct Answer: C
Rationale: Evidence-based medicine integrates research
evidence with clinical judgment and patient preferences.
Citation: Harrison’s Principles of Internal Medicine, 22nd ed.,
Ch. 1
2. Promoting Good Health (Ch. 2)
,2. Which intervention provides the greatest population-level
health benefit?
A. Advanced imaging
B. Lifestyle modification
C. Genetic testing
D. Surgical intervention
Correct Answer: B
Rationale: Health promotion through behavior modification
yields the largest reduction in morbidity and mortality.
Citation: Harrison’s Principles of Internal Medicine, 22nd ed.,
Ch. 2
3. Vaccine Opposition and Hesitancy (Ch. 3)
3. What nursing approach is most effective when addressing
vaccine hesitancy?
A. Presenting statistical risk alone
B. Dismissing patient concerns
C. Using empathetic, respectful dialogue
D. Mandating vaccination without discussion
Correct Answer: C
Rationale: Trust-building communication addressing concerns
respectfully improves vaccine acceptance.
Citation: Harrison’s Principles of Internal Medicine, 22nd ed.,
Ch. 3
, 4. Decision-Making in Clinical Medicine (Ch. 4)
4. Shared decision-making requires which key element?
A. Physician-directed choices
B. Exclusion of patient preferences
C. Clear communication of risks and benefits
D. Avoidance of uncertainty discussion
Correct Answer: C
Rationale: Patients must understand options, risks, and benefits
to participate meaningfully.
Citation: Harrison’s Principles of Internal Medicine, 22nd ed.,
Ch. 4
5. Precision Medicine and Clinical Care (Ch. 5)
5. Precision medicine primarily aims to:
A. Replace clinical assessment
B. Individualize care using genetic and molecular data
C. Standardize treatment protocols
D. Reduce diagnostic testing
Correct Answer: B
Rationale: Precision medicine tailors prevention and treatment
to individual biological differences.
Citation: Harrison’s Principles of Internal Medicine, 22nd ed.,
Ch. 5
