MARYVILLE PHARMACOLOGY EXAM 1
PRACTICE PAPER 2026 COMPLETE SOLUTIONS
◉ What is a Black Box Warning: Answer: is considered a
contraindication to administer that drug.
◉ What is the drugs half-life? Answer: Half-life specifically means
the amount of time it takes for an administered drug to be halfway
cleared from the system.
◉ Peak of action: Answer: the time between drug administration
and maximum concentration of drug in the blood stream. Best
therapeutic effect.
◉ Duration of action: Answer: the time between onset of action and
metabolism of drug below the minimum needed for an effect. The
length of time you have the drug in your system.
◉ According to the WHO what is the first step in the prescribing
process? Answer: The first step is to define the patient's problem
◉ The second step is to Answer: specify the therapeutic objective
,◉ The third step is to Answer: choose which drug or treatment is
needed.
◉ Step 4 of the WHO approach: Answer: Start the treatment
◉ Step 5 of the WHO approach: Answer: Educate the patient
◉ Step 6 of the WHO approach: Answer: Monitor the treatment
◉ Phase 1 of drug development: Answer: The drug is tested on
healthy volunteers
◉ Phase 2 of drug development: Answer: trials with people who
have the disease for which the drug is thought to be effective
◉ Phase 3 of drug development: Answer: Large numbers of patients
in medical research centers receive the drug in phase 3. This larger
sampling provides information about infrequent or rare adverse
effects. The FFA will approve a new drug application if phase 3
studies are satisfactory.
◉ Phase 4 of drug development: Answer: This phase is voluntary
and involves postmarket surveillance of the drug's therapeutic
effects at the completion of phase 3. The pharmaceutical company
, receives reports from doctors and other health care professionals
about the therapeutic results and adverse effects of the drug. Some
medications, for example, have been found to be toxic and have been
removed from the market after their initial release.
◉ Explain first pass metabolism Answer: much of the drug is lost in
the absorption process. The liver metabolizes many drugs, thus
reduces the bioavailabilty of the drug.
◉ What is the fasted route of absorption: Answer: The fastest route
of absorption is inhalation, and not as mistakenly considered the IV
administration.
◉ Why does the GI tract take longer to absorb? Answer: The GI tract
is lined with epithelial cells; drugs must permeate through these
cells in order to be absorbed into the circulatory system.
◉ What is One particular cellular barrier that may prevent
absorption of a given drug? Answer: the cell membrane. Cell
membranes are essentially lipid bilayers which form a
semipermeable membrane. Pure lipid bilayers are generally
permeable only to small and uncharged solutes, hence whether or
not a molecule is ionized will affect its absorption, since ionic
molecules are charged.
PRACTICE PAPER 2026 COMPLETE SOLUTIONS
◉ What is a Black Box Warning: Answer: is considered a
contraindication to administer that drug.
◉ What is the drugs half-life? Answer: Half-life specifically means
the amount of time it takes for an administered drug to be halfway
cleared from the system.
◉ Peak of action: Answer: the time between drug administration
and maximum concentration of drug in the blood stream. Best
therapeutic effect.
◉ Duration of action: Answer: the time between onset of action and
metabolism of drug below the minimum needed for an effect. The
length of time you have the drug in your system.
◉ According to the WHO what is the first step in the prescribing
process? Answer: The first step is to define the patient's problem
◉ The second step is to Answer: specify the therapeutic objective
,◉ The third step is to Answer: choose which drug or treatment is
needed.
◉ Step 4 of the WHO approach: Answer: Start the treatment
◉ Step 5 of the WHO approach: Answer: Educate the patient
◉ Step 6 of the WHO approach: Answer: Monitor the treatment
◉ Phase 1 of drug development: Answer: The drug is tested on
healthy volunteers
◉ Phase 2 of drug development: Answer: trials with people who
have the disease for which the drug is thought to be effective
◉ Phase 3 of drug development: Answer: Large numbers of patients
in medical research centers receive the drug in phase 3. This larger
sampling provides information about infrequent or rare adverse
effects. The FFA will approve a new drug application if phase 3
studies are satisfactory.
◉ Phase 4 of drug development: Answer: This phase is voluntary
and involves postmarket surveillance of the drug's therapeutic
effects at the completion of phase 3. The pharmaceutical company
, receives reports from doctors and other health care professionals
about the therapeutic results and adverse effects of the drug. Some
medications, for example, have been found to be toxic and have been
removed from the market after their initial release.
◉ Explain first pass metabolism Answer: much of the drug is lost in
the absorption process. The liver metabolizes many drugs, thus
reduces the bioavailabilty of the drug.
◉ What is the fasted route of absorption: Answer: The fastest route
of absorption is inhalation, and not as mistakenly considered the IV
administration.
◉ Why does the GI tract take longer to absorb? Answer: The GI tract
is lined with epithelial cells; drugs must permeate through these
cells in order to be absorbed into the circulatory system.
◉ What is One particular cellular barrier that may prevent
absorption of a given drug? Answer: the cell membrane. Cell
membranes are essentially lipid bilayers which form a
semipermeable membrane. Pure lipid bilayers are generally
permeable only to small and uncharged solutes, hence whether or
not a molecule is ionized will affect its absorption, since ionic
molecules are charged.
