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HESI A2 Anatomy & Physiology | 2026 Exam Q&A | 400+ Solved Questions | Hormones, Reproduction, Body Systems, Blood Flow

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This document contains over 400 fully solved and verified questions and answers from the 2026 HESI A2 Anatomy and Physiology Exam, designed to provide students with a comprehensive mastery of A&P content in preparation for the HESI entrance assessment. Organized in a Q&A format with straightforward answers, it covers every major system of the human body with clear definitions and test-style recall prompts. The guide thoroughly explains: Anatomical positions and directional terms (superior, distal, lateral) Histology and tissue types (epithelial, connective, muscle, nerve) Skeletal structure and bone classification Muscle anatomy and contraction (flexors, extensors, ATP use) Nervous system and brain function (neurons, CNS/PNS, cerebellum) Endocrine glands and hormone function (steroid vs. non-steroid) Circulatory and cardiac cycle (atria, valves, coronary circulation) Respiratory mechanics and gas exchange (alveoli, diaphragm) Digestive, urinary, and reproductive systems (enzymes, nephron, gametes) Hormonal regulation of pregnancy, menstrual cycle, and placenta Ideal for nursing students, pre-health candidates, and HESI A2 test-takers, this resource helps reinforce terminology and systems-based learning efficiently. It's especially suited for those seeking quick review, flashcard-style repetition, or targeted system review ahead of the 2026 HESI entrance test. Best for: Nursing and pre-nursing students Allied health and medical prep programs High school or college A&P learners HESI A2 Anatomy & Physiology 2026 candidates Keywords: HESI A2 anatomy, physiology exam, endocrine system, reproductive cycle, brain and neurons, heart anatomy, hormones, skeletal system, muscle physiology, cell division, mitosis, meiosis, urinary system, nephron, digestive enzymes, gas exchange, blood flow, placenta, estrogen, testosterone, medical entrance prep, 2026 HESI review

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HESI A2 Anatomy and Physiology 2026
Exam Questions and Answers | 100%
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Anatomic Position - 🧠ANSWER ✔✔The body is erect, the feet are slightly

apart, the head is held high, and the palms of the hands are facing forward.


Superior - 🧠ANSWER ✔✔Above


Inferior - 🧠ANSWER ✔✔Below


Anterior - 🧠ANSWER ✔✔Facing forward


Posterior - 🧠ANSWER ✔✔Toward the back

,Medial - 🧠ANSWER ✔✔Toward the midline


Lateral - 🧠ANSWER ✔✔Away from the midline; towards the side


Proximal - 🧠ANSWER ✔✔closer to point of attachment


Distal - 🧠ANSWER ✔✔Farther away from point of attachment


Histology - 🧠ANSWER ✔✔Study of tissues


Epithelial cells - 🧠ANSWER ✔✔Cover, line, and protect the body and its

internal organs


Connective tissue - 🧠ANSWER ✔✔Framework of the body, providing

support and structure for the organs; Types of Connective Tissue:

Cartilage, Adipose, and Smooth


Nerve Tissue - 🧠ANSWER ✔✔Composed of neurons


Tissue - 🧠ANSWER ✔✔Group of cells that act together to perform specific

functions


Neuroglia - 🧠ANSWER ✔✔Neurons and connective tissue cells that make

of nerve tissue

, Muscle Tissue - 🧠ANSWER ✔✔-Classified as voluntary muscle (skeletal

muscle) or involuntary muscle (smooth and cardiac muscle tissue)

-Have the ability to contract or shorten


Cell - 🧠ANSWER ✔✔Basic unit of life and the building blocks of tissues and

organs


Nucleus - 🧠ANSWER ✔✔Contains DNA


Ribosomes - 🧠ANSWER ✔✔-Synthesis of proteins


-Proteins include the enzymes that regulate all chemical reactions within

the body


Mitosis - 🧠ANSWER ✔✔-Necessary for growth and repair


-DNA is duplicated and distributed evenly to two daughter cells


Meiosis - 🧠ANSWER ✔✔-Cell division that takes place in the gonads

(ovaries and testes);

-Chromosome number reduced from 46 to 23 so when the egg and the

sperm unite in fertilization, the zygote will have correct number of

chromosomes


Skin - 🧠ANSWER ✔✔-Largest organ in the body

3
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