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Digestive System Physiology UCF Exam (100+ Q&A) – Exam 4 | BIO, GI Tract, Enzymes, Hormones, Disorders | 2025/2026

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This in-depth exam prep resource contains over 100 detailed questions and accurate answers for Exam 4 in Digestive System Physiology, covering the full gastrointestinal system from anatomy and neural regulation to digestion, absorption, and pathology. The material is based on the 2025/2026 Spring session and is aligned with advanced undergraduate physiology or human biology coursework. Key topics include: GI anatomy & function: oral cavity to rectum, muscle types, sphincters, motility patterns (peristalsis, segmentation, tonic/phasic contraction) Neural control: autonomic nervous system (vagus nerve, sympathetic/parasympathetic), enteric plexuses, neurotransmitters like ACh and VIP Hormonal regulation: gastrin, CCK, secretin, GIP, somatostatin, and their effects on secretion, motility, and feedback mechanisms Digestive enzymes & absorption: pancreatic enzymes, bile salts, brush border enzymes, and nutrient transport (GLUT2, SGLT1, lipoproteins) Disorders & clinical cases: GERD, achalasia, Crohn’s disease, Zollinger-Ellison syndrome, gallstones, jaundice, cirrhosis, Wilson’s disease, ulcers, A-beta lipoproteinemia Accessory organs: liver (bile production, detox, metabolism), pancreas (enzyme/bicarbonate secretion), gallbladder, and salivary glands Carbohydrate, lipid, and protein digestion pathways, vitamin/mineral absorption (e.g., B12, calcium), and fecal composition This guide is ideal for students in: Human Physiology, Biology, Pre-Med, and Health Sciences programs Nursing, Medical, or PA programs requiring a strong foundation in GI physiology Anyone preparing for university-level physiology exams or practicals focused on the digestive system The document is presented in a clinical-style Q&A format, helping students review efficiently and master high-yield concepts commonly tested in final exams. Keywords: digestive physiology, GI hormones, peristalsis, bile salts, enzyme secretion, vagus nerve, gastric acid, stomach cells, nutrient absorption, GERD, ulcers, gastrin, secretin, CCK, Crohn’s disease, bile production, pancreatic enzymes, intestinal motility, malabsorption, gallstones

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Digestive System Physiology Exam 4
with Dr. Ahangari Spring UCF 2025/2026
Exam Questions with 100% Correct
Answers | Latest Update



What is the first part of the body that breaks down food for absorption? -

🧠ANSWER ✔✔Oral cavity by saliva enzymes.


What is the digestive system composed of? - 🧠ANSWER ✔✔Oral cavity,

pharynx, esophagus, stomach, duodenum, jejum, ileum, large intestin

(cecum, ascending, transverse, descending, sigmoid, rectum, anal canal,

anus), Liver (Gallbladder), Spleen, Pancreas.

What are the types of muscle found in small/larga intestine and

esophagus? - 🧠ANSWER ✔✔Smooth muscles such as;

,Longitudinal, Circular.


What are the types of muscle found in stomach? - 🧠ANSWER ✔✔Smooth

muscle such as;

Longitudinal, Circular, and Oblique


How dos the NS controls peristalsis of smooth muscle? - 🧠ANSWER ✔✔It

is controlled by Enteric NS


What is the function of Enteric System? - 🧠ANSWER ✔✔Controls

peristalsis and is formed of two plexus.

Meissner and Auerbach, located inside wall of GI which innervates smooth

muscle hence controls peristalses


How does ANS controls peristalsis? - 🧠ANSWER ✔✔Sympathetic system

has a negative effect on GI (inhibits hormone secretion) by Norepinephrine

through Enteric S.

Parasympathetic system has positive effect of GI (accelerates peristalses,

endocrine hormone secretion) by ACh through Vagus Nerve

, What is the difference of Sympathetic and Parasympathetic system in GI

tract? - 🧠ANSWER ✔✔Symp has negative effect; NT is Norepinephrine;

controlled through Enteric System

Parasympathetic has positive effect; NT is ACh; controlled by CNX (vagus)


What are the GI layers of Lumen? - 🧠ANSWER ✔✔Mucus membrane,

Muscular mucosa, Muscle layer (circular longitudinal), and Serosa

(connective tissues for external protection)

What are the types of fibers and functions of ANS? - 🧠ANSWER

✔✔Efferent fibers, takes info from CNS to PNS


Afferent fibers, takes info from PNS to CNS

What is the main nerve(s) for parasympathetic system in GIT? - 🧠ANSWER

✔✔CNX (Vagus) and Pelvic Splanchnic Nerve (S2,S3,S4)


What is the innervation of sympathetic ns? - 🧠ANSWER ✔✔T5-L2


What is the difference when Circular and Longitudinal Muscles contracts? -

🧠ANSWER ✔✔Circular contraction decreases diameter of segment


Longitudinal contraction decreases length of segment




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