NURS 5334 - ANTIMICROBIAL RECALL QUIZ
Why do many medications lack pediatric dosing information in their drug labeling -
Answers -There is lack of evidence-based literature on the safe and effective use of
medications in children
Why are neonates at greater risk for toxicity with highly protein-bound drugs - Answers
-Protein binding is decreased in neonates increasing the amount of free drug available
At what age are adult levels of renal function achieved - Answers -12 months
What is the most accurate device for measuring a 2.5mL dose for a child - Answers -An
oral syringe
How do you help prevent medication errors - Answers -Write out the term daily
In pediatric patients gastric acidity does not reach adult values for - Answers -2 years
Nalidixic acid may cause _______ in children - Answers -cartilage erosion
Altered absorption of drugs in the elderly may result in _______ drug response -
Answers -Delayed
You have an elderly patient taking warfarin. You add another protein binding drug.
Which of the following statements is correct? - Answers -You will need to decrease
dose of warfarin
In elderly, proper index of renal function is _____ - Answers -Glomerular filtration rate
(GFR)
List that identifies drugs with high likelihood of cause adverse effects in elderly -
Answers -Beers list
Primary mechanism of antibacterial action of the penicillin's involve inhibition of -
Answers -Cell wall synthesis by binding and inactivating penicillin binding proteins
(PBPs)
Which statement about vancomycin is accurate - Answers -Increases bacterial cell wall
permeability and inhibits RNA synthesis
The mechanism of action of the tetracyclines involves - Answers -Inhibiting protein
synthesis
, Mechanism of action of aminoglycosides - Answers -Causes misreading of the code on
the mRNA template to inhibit protein synthesis
Which statement is accurate regarding the antibacterial action of gentamicin - Answers
-Gentamicin continues to exert antibacterial effects even after plasma level decrease
below detectable levels
If a patient was treated with the macrolide erythromycin, he/she should - Answers -
Temporarily stop simvastatin while taking erythromycin
24 year old woman returned from vacation abroad suffering from traveler's diarrhea, and
her problem has not responded to antidiarrheal drugs. A pathogenic gram-negative
bacillus is suspected. Which drug is most likely to be effective in the treatment of this
patient - Answers -Ciprofloxacin
Which is accurate about fluoroquinolones - Answers -Fluoroquinolones have different
therapeutic applications depending on the generation
Which adverse effect is MOST LIKELY to occur with sulfonamides - Answers -Skin
reactions
Which is true about ciprofloxacin - Answers -During treatment, tendonitis and even
tendon rupture may occur
Primary reason for the use of drug combinations in treatment of TB is to - Answers -
Delay or prevent emergence of resistance
Which is true about fluconazole - Answers -Primary route of excretion is renal
55 year old man has been on anticoagulant treatment for many years and is newly
diagnosed with TB. Which of the following antimycobacterial agents would MOST
LIKELY induce cytochrome P450 enzymes in the patient's liver thereby modifying the
effects of his anticoagulant treatment - Answers -Rifampin
Which drug is an antiviral that can be used to decrease shedding with genital herpes -
Answers -Valacyclovir
First generation cephalosporins are best against which organism - Answers -Gram
positive cocci
Cefepime is eliminated via - Answers -Tubular secretion and or glomerular filtration
Which cephalosporins cause bleeding tendencies - Answers -cefotetan and ceftriaxone
Which cephalosporins induce alcohol intolerance - Answers -Cefotetan and Cefazolin
Why do many medications lack pediatric dosing information in their drug labeling -
Answers -There is lack of evidence-based literature on the safe and effective use of
medications in children
Why are neonates at greater risk for toxicity with highly protein-bound drugs - Answers
-Protein binding is decreased in neonates increasing the amount of free drug available
At what age are adult levels of renal function achieved - Answers -12 months
What is the most accurate device for measuring a 2.5mL dose for a child - Answers -An
oral syringe
How do you help prevent medication errors - Answers -Write out the term daily
In pediatric patients gastric acidity does not reach adult values for - Answers -2 years
Nalidixic acid may cause _______ in children - Answers -cartilage erosion
Altered absorption of drugs in the elderly may result in _______ drug response -
Answers -Delayed
You have an elderly patient taking warfarin. You add another protein binding drug.
Which of the following statements is correct? - Answers -You will need to decrease
dose of warfarin
In elderly, proper index of renal function is _____ - Answers -Glomerular filtration rate
(GFR)
List that identifies drugs with high likelihood of cause adverse effects in elderly -
Answers -Beers list
Primary mechanism of antibacterial action of the penicillin's involve inhibition of -
Answers -Cell wall synthesis by binding and inactivating penicillin binding proteins
(PBPs)
Which statement about vancomycin is accurate - Answers -Increases bacterial cell wall
permeability and inhibits RNA synthesis
The mechanism of action of the tetracyclines involves - Answers -Inhibiting protein
synthesis
, Mechanism of action of aminoglycosides - Answers -Causes misreading of the code on
the mRNA template to inhibit protein synthesis
Which statement is accurate regarding the antibacterial action of gentamicin - Answers
-Gentamicin continues to exert antibacterial effects even after plasma level decrease
below detectable levels
If a patient was treated with the macrolide erythromycin, he/she should - Answers -
Temporarily stop simvastatin while taking erythromycin
24 year old woman returned from vacation abroad suffering from traveler's diarrhea, and
her problem has not responded to antidiarrheal drugs. A pathogenic gram-negative
bacillus is suspected. Which drug is most likely to be effective in the treatment of this
patient - Answers -Ciprofloxacin
Which is accurate about fluoroquinolones - Answers -Fluoroquinolones have different
therapeutic applications depending on the generation
Which adverse effect is MOST LIKELY to occur with sulfonamides - Answers -Skin
reactions
Which is true about ciprofloxacin - Answers -During treatment, tendonitis and even
tendon rupture may occur
Primary reason for the use of drug combinations in treatment of TB is to - Answers -
Delay or prevent emergence of resistance
Which is true about fluconazole - Answers -Primary route of excretion is renal
55 year old man has been on anticoagulant treatment for many years and is newly
diagnosed with TB. Which of the following antimycobacterial agents would MOST
LIKELY induce cytochrome P450 enzymes in the patient's liver thereby modifying the
effects of his anticoagulant treatment - Answers -Rifampin
Which drug is an antiviral that can be used to decrease shedding with genital herpes -
Answers -Valacyclovir
First generation cephalosporins are best against which organism - Answers -Gram
positive cocci
Cefepime is eliminated via - Answers -Tubular secretion and or glomerular filtration
Which cephalosporins cause bleeding tendencies - Answers -cefotetan and ceftriaxone
Which cephalosporins induce alcohol intolerance - Answers -Cefotetan and Cefazolin
