Nurs 5315 Uta Exam 2 |Actual
Questions And Perfect Answers
What is the etiology, incubation, and mode of transmission for influenza - correct-
answer -Comes from one of three types- A, B, C
Transmitted via aerosol
Incubation is 1-4 days (usually 2)
What is the etiology, incubation, and mode of transmission for measles - correct-
answer -Initial infection and viral replication occur locally in tracheal and bronchial
epithelial cells. After 2-4 days, local lymphatic tissues are infected. Virus is
disseminated to various organs, and rash appears.
Transmitted by respiratory droplets, either airborne or on surfaces up to 2 hours
Incubated 7-14 days (average 10-12 days)
What is the etiology, incubation, and mode of transmission for HIV - correct-
answer -Virus enters bloodstream and begins seeking out the CD4 (T-helper cells).
The virus fuses to CD4 cells and integrates with host's DNA. More CD4 cells
become infected, and eventually rupture. Overall CD4 count is reduced, leaving
patient susceptible to opportunist infections.
Transmitted via bodily fluids-blood borne.
Incubates as long as 10 years in untreated individuals.
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Discuss some clinical implications of solid organ transplant rejection - correct-
answer -rejection is an immune response, mostly T-cell mediated. Slow process,
Type 4 hypersensitivity
Patients are highly susceptible to infections r/t use of immunosuppressants
Describe the role of HLA in solid organ rejections - correct-answer -HLA is typed
and matched on donor and recipient to decrease risk of rejection
HLA is targeted response for rejection
clinical manifestations of influenza - correct-answer -fever, sore throat, myalgias,
headache, nasal discharge, weakness and severe fatigue, cough and other
respiratory symptoms, tachycardia, red, watery eyes, pharyngitis
clinical implications of influenza - correct-answer -prevention is key- vaccinate at
6+ months, annual
diagnosed by rapid swab
treat with antivirals- Tamiflu
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clinical manifestations of measles - correct-answer -fever >104, lasts 4-7 days,
malaise, anorexia, 3c's- conjunctivitis, cough, coryza (inflammation of mucous
membrane of nose), photophobia, periorbital edema, myalgias, Koplik spots
(bluish-gray specks on red base, on buccal mucosa), rash- begins at hairline,
spreads in 48 hours
Clinical implications of measeles - correct-answer -One of most contagious
infectious diseases, lasts 7-10 days
Educate parents on importance of vaccination
Immune globulin can be administered within 6 days of exposure
Can be fatal for HIV patients
Immunocompromised may have no rash
Need serologic testing per CDC
Tx is supportive- rehydration, Vit A
Antiretroviral medications - correct-answer -Used to impede viral replication of
HIV virus, come in 6 classes
1. Nucleoside reverse transcriptase inhibitors
2. Non-nucleoside reverse transcriptase inhibitors
3. Protease inhibitors
4. CCR5 inhibitors- inhibits binding to CCR3
5. Fusion inhibitor- inhibits fusion between HIV and cell membrane
6. Integrate inhibitor- inhibits viral integrate enzyme