2026 SOLVED ITEMS CONFIRMED A+
◉ <140/90. Answer: JNC8 BP goal for pts of all ages w/ diabetes but
no CKD
◉ <140/90. Answer: JNC8 BP goal for pts of all ages w/ CKD but no
diabetes
◉ no matter race or age, all pts w/ HTN & CKD must be started on
either an ACE-I or ARB. Answer: how is treatment different for CKD
hypertensive pts according to JNC8?
◉ ACE-I, ARB, thiazide diuretic, CCB. Answer: first-line tx options for
HTN
◉ - all adults 140+/90+
- 130-139/80-89 & CVD or 10-yr ASCVD of 10%+. Answer: when is
anti-HTN drug therapy started according to ACC/AHA guidelines?
◉ <130/80. Answer: BP goal for all adults w/ HTN according to
ACC/AHA guidelines
,◉ <120 & <80. Answer: normal blood pressure numbers
◉ 120-129 & <80. Answer: elevated blood pressure numbers
◉ 130-139 or 80-89. Answer: HTN Stage 1 numbers
◉ 140+ or 90+. Answer: HTN Stage 2 numbers
◉ anuria
sulfa allergies. Answer: C/I to using thiazide diuretics for HTN
◉ competitively block HMG-CoA reductase. Answer: MOA of statins
◉ inc LFTs, myopathy, rhabdo, inc CK, inc blood sugar. Answer: side
effects of statins
◉ bile acid binding resin --> prevent recycling of bile acids to liver
leading to synthesis of new bile acids & depletion of liver cholesterol
stores. Answer: MOA of cholestyramine
◉ impair fat-soluble vitamin absorption
dec statin absorption
, gallstones, constipation, bloating. Answer: side effects of
cholestyramine
◉ blocks intestinal absorption of cholesterol. Answer: MOA of
ezetimibe
◉ steatorrhea/diarrhea
abdominal pain/discomfort. Answer: side effects of ezetimibe
◉ activate PPAR-alpha to upregulate LPL. Answer: MOA of fibrates
(gemfibrozil, fenofibrate)
◉ cholesterol gallstones, inc myopathy risk w/ statins, leg cramps.
Answer: side effects of fibrates
◉ directly & noncompetitively inhibits hepatocyte diacylglycerol
acyltransferase-2
(most effective for increasing HDL). Answer: MOA of niacin
◉ severe hepatotoxicity, hyperuricemia, cutaneous flushing &
warmth, hyperglycemia. Answer: side effects of niacin
◉ NSAIDs. Answer: what can be given to combat the flushing &
warmth caused by niacin?