questions / High-Yield & Frequently Missed
ABSITE Questions
Breast: What is presentation, treatment, prognosis for intraductal papilloma? - --
-✔✔✔ANSWER----presents with bleeding/bloody nipple discharge (most
common cause), usually benign, biopsy/resect via major duct excision
Breast: What are contraindications to BCT (lumpectomy) in stage I breast cancer
(and what specifically is not)? - ---✔✔✔ANSWER----1) prior irradiation;
2) pos margins;
3) inflammatory;
4) pregnancy (unless 3rd trimester)
Breast: what are the axillary node levels (1-3, and one more category)? - ---
✔✔✔ANSWER----1 - lateral to pec minor;
,2 - beneath pec minor;
3 - medial to pec minor;
Rotter's Nodes - between pec major and pec minor
Breast: when is SNLB indicated (size, nodes, tumor status, metastatic risk)>? - ---
✔✔✔ANSWER---->1 cm, no positive nodes (obviously), primary tumor
present, low risk of axillary mets,
Breast: what do you do if you can't find radiotracer dye in SNLB? - ---
✔✔✔ANSWER----have to do formal ALND
Breast: what is treatment for DCIS in male/female? - ---✔✔✔ANSWER----
female -- BCT + xrt OR mastectomy; male -- mastectomy
Breast: what is not needed for patient with negative SLNB? - ---
✔✔✔ANSWER----ALND -- just do BCT or mastectomy depending on tumor
is fine
Breast: what patient would get only mastectomy/BCT + tamoxifen for 5 years (4
characteristics)? - ---✔✔✔ANSWER----negative SLN, old, ER+, and tumor
<2 cm
,Breast: what patient would get mastectomy/BCT + tamoxifen for 5 years plus
chemo (4 characteristics)? - ---✔✔✔ANSWER----negative SLN, young, ER+,
and tumor >1cm
Breast: what are 3 chemo agents used for breast CA typically? - ---
✔✔✔ANSWER----1) adriamycin; 2) cyclophosphamide; 3) taxol
Breast: what patient would get mastectomy/BCT + chemo (no tamoxifen)? - ---
✔✔✔ANSWER----negative SLN, ER-
Breast: what is main SE of taxol? - ---✔✔✔ANSWER----taxol - neuropathy
Breast: what is main SE of adriamycin (doxorubacin)? - ---✔✔✔ANSWER--
--cardiomyopathy
Breast: what is treatment for inflammatory breast cancer (in order)? - ---
✔✔✔ANSWER----neoadjuvant chemo, then mastectomy (mod radical),
then XRT
Breast: what options are available for breast mass post neoadjuvant therapy? - --
-✔✔✔ANSWER----same as de novo breast cancer -- BCT or mastectomy --
if tumor shrunk and now amenable to BCT, that's fine, even if it was big before
and needed mastectomy based on size
, Breast: LCIS -- who primarily gets this, what is most important characteristic, what
% get cancer, where, and what type? - ---✔✔✔ANSWER----- pre-
menopausal
- NOT premalignant itself
- 30% lifetime risk
70% ductal CA
Breast: LCIS -- what % have synchronous cancer? - ---✔✔✔ANSWER----5%
Breast: LCIS -- what is treatment (4 possibility, 2 things not needed ever)? - ---
✔✔✔ANSWER----1) Need to resect the lesion but do not need neg margins
2) nothing and careful F/U
3) Hormonal therapy
-(pre-meno: tamoxifen; Post-meno: raloxifene)
4) bilateral subcutaneous mastectomy (no ALND)
Breast: What are the benign proliferative breast lesions that have increased risk of
CA? (3)
Tx? - ---✔✔✔ANSWER----- LCIS
- Atypical ductal hyperplasia
- atypical lobular hyperplasia
Tx: resect the lesion w/ (-) margins