ABSITE 2026 ABSITE Surgery Exam | High-Yield
Review Questions & Answers
What is the MOA and use for vandetanib? - correct answer-Inhibits
VEGF2/3, EGFR, RET - used for medullary thyroid CA (ZETA study)
What is the MOA and use for pembrolizumab - correct answer-
Antibody blocking programmed cell death protein-1 - used for
melanoma
MOA and use of ipilimumab - correct answer-antibody blocking
cytotoxic T lymphocyte-associated protein-4 (CTLA4) - used for
melanoma
MOA and use of cetuximab - correct answer-inhibits endothelial growth
factor receptor - used for colorectal cancer
MOA and use of imatinib - correct answer-inhibits tyrorsine kinase
receptor - used for GIST
What antibiotic is used in necrotizing pancreatitis? - correct answer-
Imipenem (best penetration)
,how long is activity restriction after blunt spleen/liver injury? - correct
answer-grade + 2 weeks (aka grade 2 = 4 weeks)
Which side is mattox? Cattel-braasch? - correct answer-left is mattox,
right is cattel
what kind of stent is used in esophageal perforation? - correct answer-
covered self-expanding metal stent
these two structures are ligated in the cervical exposure of the
esophagus - correct answer-middle thyroid vein, inferior thyroid artery
aspirin MOA - correct answer-irreversible inhibition of prostaglandin
synthesis in platelets that acts by acetylating COX
What are the first and second most common salivary gland tumors? -
correct answer-1. Pleomorphic adenoma
2. Warthin tumor (papillary cystadenoma lymphomatosum) (smoking)
What is the strongest independent prognostic factor for soft tissue
sarcomas? - correct answer-histologic grade
, what size femoral artery pseudoaneurysm can be ovserved? - correct
answer-<2-3 cm
Where are the acid-secreting cells of the stomach? - correct answer-
body - parietal cells
Gastrin-secreting G cells are in antrum
The mutation of PTEN is what disease and presentation? - correct
answer-Cowden - hamartomas and thyroid, endometrial, and colon
cancer (Poop, Thyroid, Endometrial Neoplasm = PTEN)
RET protooncogene mutation is seen in what disease and presentation -
correct answer-MEN2 = medullary thyroid cancer, pheo and MEN2A
(parathyroid hyperplasia) and MEN2B (marfanoid, neuromas)
TP53 mutation results in what disease and presentation? - correct
answer-Li-fraumeni - bone/soft tissue sarcomas, phyllodes tumor, brain
tumor, adrenocorticoid cancer
STK11 results in what disease and presentation - correct answer-Peutz-
Jeghers (aut dom GI hamartomas, mucocutaneous pigmentation, and
GI cancer)
what diet is best for pancreatic insufficiency? - correct answer-High
carb, high protein, low fat +pancreatic enzyme supplement
Review Questions & Answers
What is the MOA and use for vandetanib? - correct answer-Inhibits
VEGF2/3, EGFR, RET - used for medullary thyroid CA (ZETA study)
What is the MOA and use for pembrolizumab - correct answer-
Antibody blocking programmed cell death protein-1 - used for
melanoma
MOA and use of ipilimumab - correct answer-antibody blocking
cytotoxic T lymphocyte-associated protein-4 (CTLA4) - used for
melanoma
MOA and use of cetuximab - correct answer-inhibits endothelial growth
factor receptor - used for colorectal cancer
MOA and use of imatinib - correct answer-inhibits tyrorsine kinase
receptor - used for GIST
What antibiotic is used in necrotizing pancreatitis? - correct answer-
Imipenem (best penetration)
,how long is activity restriction after blunt spleen/liver injury? - correct
answer-grade + 2 weeks (aka grade 2 = 4 weeks)
Which side is mattox? Cattel-braasch? - correct answer-left is mattox,
right is cattel
what kind of stent is used in esophageal perforation? - correct answer-
covered self-expanding metal stent
these two structures are ligated in the cervical exposure of the
esophagus - correct answer-middle thyroid vein, inferior thyroid artery
aspirin MOA - correct answer-irreversible inhibition of prostaglandin
synthesis in platelets that acts by acetylating COX
What are the first and second most common salivary gland tumors? -
correct answer-1. Pleomorphic adenoma
2. Warthin tumor (papillary cystadenoma lymphomatosum) (smoking)
What is the strongest independent prognostic factor for soft tissue
sarcomas? - correct answer-histologic grade
, what size femoral artery pseudoaneurysm can be ovserved? - correct
answer-<2-3 cm
Where are the acid-secreting cells of the stomach? - correct answer-
body - parietal cells
Gastrin-secreting G cells are in antrum
The mutation of PTEN is what disease and presentation? - correct
answer-Cowden - hamartomas and thyroid, endometrial, and colon
cancer (Poop, Thyroid, Endometrial Neoplasm = PTEN)
RET protooncogene mutation is seen in what disease and presentation -
correct answer-MEN2 = medullary thyroid cancer, pheo and MEN2A
(parathyroid hyperplasia) and MEN2B (marfanoid, neuromas)
TP53 mutation results in what disease and presentation? - correct
answer-Li-fraumeni - bone/soft tissue sarcomas, phyllodes tumor, brain
tumor, adrenocorticoid cancer
STK11 results in what disease and presentation - correct answer-Peutz-
Jeghers (aut dom GI hamartomas, mucocutaneous pigmentation, and
GI cancer)
what diet is best for pancreatic insufficiency? - correct answer-High
carb, high protein, low fat +pancreatic enzyme supplement
