UNDERSTANDING PATHOPHYSIOLOGY 7TH EDITION BY HUETHER & MCCANCE TEST BANK/COMPLETE GUIDE 2026

,Chapter 1. Cellular Biology c2 c2 c2




MULTIPLECHOICE c2




1. Astudent is observinga cellunder the microscope. It is observed to have supercoiled DNA with
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c2 histones. Which of the following would also be observed by the student?
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a. Asinglecircular chromosome c2 c2 c2




b. A nucleus c2




c. Free-floatingnuclear material c2 c2




d. No organelles c2




ANS:B c2




The celldescribed isa eukaryotic cell, so it has histones and a supercoiled DNAwithin its nucleus;
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c2 thus, the nucleus should be observed.
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Asingle circular chromosome ischaracteristic ofprokaryotic cells, whichdo not have histones.
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Free-floating nuclear materialdescribesa prokaryoticcell,whichwouldnot haveadistinct nucleus.
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Eukaryoticcellshave membraneboundedcellularcomponentscalledorganelles. Noorganelles describes
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c2 a prokaryotic cell.
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2. Anurse is instructing thestaffabout cellular functions. Whichcellular function isthenurse
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c2 describing when an isolated cell absorbs oxygen and uses it to transform nutrients to energy?
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a. Metabolic absorption c2




b. Communication
c. Secretion
d. Respiration

,ANS: D c2




The abilityof the cellto absorb oxygen refers to the cells function ofrespiration.
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The abilityofthe cell to function within a societyofcells refers to its function of communication.
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The abilityof the cellto take in nutrients refers to the cells function of metabolic absorption.
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The abilityofthe cellto synthesize new substances and secrete these elsewhere refers tothe cells function of
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c2 secretion.

3. Aeukaryotic cell is undergoing DNAreplication. Inwhich region ofthe cellwould most of the
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c2 genetic information be contained? c2 c2 c2




a. Mitochondria
b. Ribosome
c. Nucleolus
d. Nucleus


ANS:C c2




The regionofthe cellthat containsgenetic material, including a large amount ofribonucleic acid,
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c2 most of the DNA, and DNA-binding proteins, is the nucleolus.
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The mitochondria is the siteofcellular respiration.
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Theribosomes are involved in manufacturing ofproteins withinthe cell.
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Thenucleus contains the nucleolus, and it isthe nucleolus that contains genetic material.
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4. The fluid mosaic modelforbiologic membranesdescribes membrane behavior. Accordingto this
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c2 model, which of the following float singly or as aggregates in the fluid lipid bilayer?
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a. Peripheralmembrane proteins c2 c2




b. Integralmembrane proteins c2 c2

, c. Glycoproteins
d. Cell adhesion molecules c2 c2




ANS:B c2




Integralmembrane proteins float freely inthe fluid lipid bilayer.
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Peripheralmembraneproteinsarenot embedded inthe layer, but resideat thesurface. Glycoproteins
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c2 act as cell surface markers.
c2 c2 c2 c2




Celladhesion molecules are onthe outside ofthe membrane and allow cells to hooktogether.
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5. Whichofthe following canbind to plasma membrane receptors?
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a. Oxygen
b. Ribosomes
c. Amphipathic lipids c2




d. Ligands


ANS: D c2




Ligands arespecific molecules that canbind withreceptorsonthe cell membrane. Oxygen
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c2 moves by diffusion; it does not bind to receptors.
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Ribosomes makeproteinsandarenot involved inbinding. c2 c2 c2 c2 c2 c2 c2 c2




c2 Amphipathic lipids are a portion of the cell membrane. c2 c2 c2 c2 c2 c2 c2 c2




6. Anurse isreviewing areport fromapatient with metastatic cancer. What finding would
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c2 supportthediagnosis ofmetastaticcancer?Alterations inextracellular matrixthat include:
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a. Decreased fibronectin c2




b. Increased collagen c2




c. Decreasedelastin c2