WEEK 1 WALDEN 6501 ADVANCED PATHOPHYSIOLOGY
QUESTIONS WITH CORRECT ANSWERS 2025/2026
Acrocentric r- rCORRECT rANSWER r-refers rto rthe rterminal rlocation rof rcentromere ron
rchromosomes r13, r14, r15, r21, rand r22
Allelic rheterogeneity r- rCORRECT rANSWER r-the rsituation rin rwhich rmultiple ralleles rat ra rsingle
rlocus rcan rproduce rone ror rmore rdisease rphenotypes.
Amorphic r- rCORRECT rANSWER r-refers rro rmutations rthat rcause ra rcomplete rloss rof rfunction
rfor rthe rrespective rgene, rand rtherefore ryield rthe rsame rphenotype ras ra rcomplete rgene
rdeletion.
Aneuploidy r- rCORRECT rANSWER r-a rgeneral rterm rused rto rdenote rany runbalanced
rchromosome rcomplement
Antimorphic r- rCORRECT rANSWER r-refers rto rmutations rthat rwhen rpresent rin rheterozygous
rform ropposite ra rnonmutant rallele rwill rresult rin ra rphenotype rsimilar rto rhomozygous rfor
rloss rof rfunction ralleles.
, Ascertainment rbias r- rCORRECT rANSWER r-the rsituation rin rwhich rindividuals ror rfamilies rin ra
rgenetic rstudy rare rnot rrepresentative rof rthe rgeneral rpopulation rbecause rof rthe rway rin
rwhich rthey rare ridentified
Autosomal r- rCORRECT rANSWER r-located ron rchromosomes r1-22 rrather rthan rx ror ry
Cpg risland r- rCORRECT rANSWER r-a rsegment rof rDNA rthat rcontains ra rrelatively rhigh rdensity
rof r5' r-
CG-3' rdinucleotides. rSuch rsegments rare rfrequently runmethylated rand rlocated rclose rto
rubiquitously rexpressed rgenes.
QUESTIONS WITH CORRECT ANSWERS 2025/2026
Acrocentric r- rCORRECT rANSWER r-refers rto rthe rterminal rlocation rof rcentromere ron
rchromosomes r13, r14, r15, r21, rand r22
Allelic rheterogeneity r- rCORRECT rANSWER r-the rsituation rin rwhich rmultiple ralleles rat ra rsingle
rlocus rcan rproduce rone ror rmore rdisease rphenotypes.
Amorphic r- rCORRECT rANSWER r-refers rro rmutations rthat rcause ra rcomplete rloss rof rfunction
rfor rthe rrespective rgene, rand rtherefore ryield rthe rsame rphenotype ras ra rcomplete rgene
rdeletion.
Aneuploidy r- rCORRECT rANSWER r-a rgeneral rterm rused rto rdenote rany runbalanced
rchromosome rcomplement
Antimorphic r- rCORRECT rANSWER r-refers rto rmutations rthat rwhen rpresent rin rheterozygous
rform ropposite ra rnonmutant rallele rwill rresult rin ra rphenotype rsimilar rto rhomozygous rfor
rloss rof rfunction ralleles.
, Ascertainment rbias r- rCORRECT rANSWER r-the rsituation rin rwhich rindividuals ror rfamilies rin ra
rgenetic rstudy rare rnot rrepresentative rof rthe rgeneral rpopulation rbecause rof rthe rway rin
rwhich rthey rare ridentified
Autosomal r- rCORRECT rANSWER r-located ron rchromosomes r1-22 rrather rthan rx ror ry
Cpg risland r- rCORRECT rANSWER r-a rsegment rof rDNA rthat rcontains ra rrelatively rhigh rdensity
rof r5' r-
CG-3' rdinucleotides. rSuch rsegments rare rfrequently runmethylated rand rlocated rclose rto
rubiquitously rexpressed rgenes.
