answ er s w ith accu r ate
r ationales(PASSED)
first line of defense - answer External Physical Barriers - Skin and mucous
membranes
Made up of structures, chemicals, and processes that work to prevent pathogens
entering the body.
Includes the skin and mucous membranes of the respiratory, digestive, urinary,
and reproductive systems.
4 cardinal signs of inflammation (plus bonus sign) - answer Heat, Pain, Redness,
Swelling AND loss of function sometimes
Smoking and many analgesic drugs (painkillers) leads to an increased risk of
infection of the respiratory and digestive tract. Why? - answer Smoking impairs
the ciliated cells of the respiratory tract.
Analgesic drugs impair peristalsis(the churning motion of the digestive tract). This
leads to an increased risk of infection in their respective areas.
Pyrogens - answer fever-inducing substances
, Plasma cells - answer plasma cell secretes Ab's. Ab's circulate through the body,
attacking antigenic determinants. (a fully differentiated B cell that produces a
single type of antibody)
Memory cells - answer Some B cells form long-lived memory B cells which
respond quickly if antigen encountered again
Antigens - answer Antigen comes from ANTIbody GENerator.
Describes a molecule that reacts specifically with antibody, a B-cell receptor, or a
T-cell receptor
Antibodies - answer Structure: Y shaped proteins. Monomer unit made of four
chains of amino acids held together by disulfides bonds. Two chains are heavy,
Two chains are light. Each heavy and light chain has a constant and a variable
region.
Has 2 parts:
-Two identical arms- Fab region ( antigen binding)- variable region is unique to
each Ab and accounts for specificity
-The Stem- Fc region (crystallized)- Constant region- Allows immune system
components to recognize otherwise diverse antibody molecules
Immunogens - answer Antigen that elicits/causes immune response called an
________________.
Example, normal protein from host A that elicits an immune response in host B is
an antigen but is only an immunogen for host B