HESI A2 Study Guide 2026 | Practice Questions & Exam Prep for Nursing Students

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HESI A2 Anatomy & Physiology Practice Test NEWEST 2026 ACTUAL EXAM
TEST- COMPLETE REAL EXAM QUESTIONS AND CORRECT DETAILED
ANSWERS (VERIFIED ANSWERS 4 VERSIONS) ALREADY GRADED A+
(MOST RECENT!!)


HESI A2 Anatomy & Physiology Practice
Test

Skeletal System
1. How many bones are in the adult human body?
A. 201
B. 206
C. 210
D. 215

Rationale: Adults have 206 bones.



2. The axial skeleton includes:
A. Skull, vertebral column, ribs, sternum
B. Arms and legs
C. Pelvis and shoulder
D. Hands and feet



3. The longest bone in the body is:
A. Humerus
B. Tibia
C. Femur
D. Radius



4. Which type of joint allows for rotation in multiple planes?
A. Hinge
B. Ball-and-socket
C. Pivot
D. Saddle


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5. The bone that protects the brain is the:
A. Mandible
B. Sternum
C. Skull
D. Scapula




Muscular System
6. Which type of muscle is voluntary and striated?
A. Smooth
B. Skeletal
C. Cardiac
D. Involuntary



7. The heart is made of which type of muscle?
A. Skeletal
B. Smooth
C. Cardiac
D. Striated voluntary



8. Muscles attach to bones via:
A. Ligaments
B. Tendons
C. Cartilage
D. Fascia



9. Which muscle type lines hollow organs like intestines?
A. Skeletal
B. Cardiac
C. Smooth
D. Striated




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10. The biceps brachii is responsible for:
A. Elbow flexion
B. Elbow extension
C. Shoulder abduction
D. Wrist rotation




Cardiovascular System
11. How many chambers does the heart have?
A. 2
B. 3
C. 4
D. 5



12. Which vessel carries oxygenated blood from the lungs to the heart?
A. Pulmonary artery
B. Pulmonary vein
C. Aorta
D. Vena cava



13. The right side of the heart pumps blood to:
A. Lungs
B. Body
C. Brain
D. Liver



14. Blood leaves the left ventricle through the:
A. Pulmonary artery
B. Aorta
C. Vena cava
D. Pulmonary vein



15. The liquid portion of blood is called:
A. Plasma
B. Serum


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C. Hemoglobin
D. Platelets




Respiratory System
16. The primary muscle of respiration is:
A. Intercostals
B. Diaphragm
C. Sternocleidomastoid
D. Rectus abdominis



17. Gas exchange occurs in the:
A. Bronchi
B. Trachea
C. Alveoli
D. Larynx



18. Which structure prevents food from entering the trachea?
A. Epiglottis
B. Larynx
C. Bronchi
D. Pharynx



19. Air moves from the pharynx to:
A. Bronchi
B. Larynx
C. Alveoli
D. Trachea



20. Which gas is expelled during exhalation?
A. Oxygen
B. Nitrogen
C. Carbon dioxide
D. Hydrogen



2026 2027 GRADED A+