Midterm Exam: NR 567/ NR567 (2026/ 2027) Advanced Pharmacology for the AGACNP Guide | Questions & Answers | Grade A| 100% Correct (Verified Solutions)-Chamberlain

Midterml Exam:l NRl 567/l NR567l (NEWl
2026/l 2027l Update)l Advancedl
Pharmacologyl forl thel AGACNPl Reviewl |l
Questionsl &l Answersl |l Gradel A|l 100%l
Correctl (Verifiedl Solutions)-Chamberlain

QUESTION
Whatl arel thel contraindicationsl forl Lidocainel withl epinephrine?

Answer:
Itl shouldl notl bel usedl forl IVl administrationl andl isl contraindicatedl inl areasl withl end-
arteriall supply.



QUESTION
Howl doesl Lidocainel functionl asl al locall anesthetic?

Answer:
Itl inhibitsl sodiuml channelsl onl neuronall celll membranes,l haltingl nervel impulsel
propagation.



QUESTION
Whatl isl thel typicall concentrationl andl onsetl timel forl Lidocaine?

Answer:
Usuallyl givenl asl al 1%l solution,l withl anl onsetl ofl aboutl 2-5l minutes.



QUESTION
Whatl isl thel maximuml dosel ofl Lidocainel withoutl epinephrine?

,Answer:
4l mg/kg.



QUESTION
Whatl isl thel maximuml dosel ofl Bupivacainel withoutl epinephrine?

Answer:
2l mg/kg.



QUESTION
Whatl arel thel characteristicsl ofl Bupivacainel comparedl tol Lidocaine?

Answer:
Bupivacainel isl morel potentl withl al longerl durationl ofl action,l lastingl upl tol sixl hours.



QUESTION
Whatl isl Procainel primarilyl usedl for?

Answer:
Dentall proceduresl andl inl patientsl withl amidel allergies.



QUESTION
Whatl arel thel CNSl andl cardiovascularl sidel effectsl associatedl withl locall anesthetics?

Answer:
CNSl effectsl includel dizzinessl andl tremors;l cardiovascularl effectsl includel hypotensionl
andl arrhythmias.



QUESTION
Whatl isl thel effectl ofl addingl epinephrinel tol Lidocainel forl locall anesthesia?

Answer:

,Itl actsl asl al vasoconstrictor,l prolongingl thel anestheticl effectl andl reducingl bleeding.



QUESTION
Whatl precautionsl shouldl bel takenl whenl usingl anestheticsl inl clientsl withl cardiacl
dysfunction?

Answer:
Usel cautiouslyl inl clientsl withl cardiacl dysfunction.



QUESTION
Whyl shouldl locall anestheticsl bel usedl cautiouslyl inl clientsl withl liverl disease?

Answer:
Duel tol hepaticl metabolism.



QUESTION
Whatl isl al criticall considerationl forl topicall formsl ofl locall anesthetics?

Answer:
Ensurel skinl isl intact,l asl brokenl skinl enhancesl thel riskl ofl systemicl absorption.



QUESTION
Whatl testl shouldl bel monitoredl duel tol thel hepaticl metabolisml ofl lidocaine?

Answer:
Liverl functionl test.



QUESTION
Howl doesl addingl sodiuml bicarbonatel tol locall anestheticsl affectl pain?

Answer:
Itl increasesl thel pHl tol decreasel pain.

, QUESTION
Whatl arel somel sidel effectsl ofl inhaledl anestheticsl likel Isoflurane?

Answer:
Respiratoryl depression,l hypotension,l malignantl hyperthermia,l GIl effectsl (N/V),l increasedl
ICP,l shivering,l hepaticl effectsl (increasel inl liverl enzymes),l andl arrhythmias.



QUESTION
Whatl isl thel mechanisml ofl actionl (MOA)l ofl Succinylcholine?

Answer:
Itl bindsl tol nicotinicl receptorsl atl thel neuromuscularl junction,l causingl depolarizationl andl
initiall musclel contraction,l leadingl tol sustainedl flaccidl musclel paralysis.



QUESTION
Whatl arel thel sidel effectsl ofl Succinylcholine?

Answer:
Hyperkalemia,l apnea,l increasedl pressurel inl thel body,l malignantl hyperthermia,l cardiacl
effectsl (bradycardial orl tachycardia),l andl myalgia.



QUESTION
Whatl monitoringl isl requiredl forl clientsl receivingl Succinylcholine?

Answer:
Monitorl BMPl forl potassiuml levelsl andl cholinesterasel plasmal levelsl inl clientsl withl
suspectedl familiall pseudocholinesterasel deficiency.



QUESTION
Whatl isl thel typicall dosingl forl Succinylcholinel duringl intubation?