SARAH MICHELLE LIVE REVIEW STUDY GUIDE
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Level
What is the normal range for TSH? 0.5-5.0
If thyroid screening of TSH comes back abnormal, then we will reorder TSH and T3,
When do you order a full thyroid profile?
T4.
What disorder demonstrates a low TSH level and Hyperthyroidism
high T3 and T4 levels?
What disorder demonstrates a high TSH level and Hypothyroidism
low T3 and T4 levels?
What medication is used to treat hypothyroidism? Levothyroxine (Synthroid)
If patient is elderly or if they have a significant cardiac history then we are going to
What dose of Synthroid do you want to start your
start at a lower dose of 12.5-25 mcg po daily.
patient on?
In a normal healthy patient, we will start at 25-50 mcg po daily.
After initiation of medication for treatment of 6-8 weeks
hypothyroidism, when do you recheck TSH level?
When TSH level is stabilized, how often do you Every 6-12 months
recheck their level?
What is the go to medication for treatment of Tapazole and PTU
hyperthyroidism?
How do you manage treatment for hyperthyroidism We need to use PTU instead if they are in their first trimester. After first trimester,
in a pregnant patient? then they can be switched to tapazole.
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What medication class is used to treat symptoms of Beta-blockers- these help manage tachycardia and palpitations
hyperthyroidism?
What are 2 other treatments for the Thyroidectomy and radioactive iodine
hyperthyroidism?
What labs are used to measure and evaluate kidney GFR, BUN, Creatinine
function?
What lab value is most accurate description of GFR- this is going to tell us how the kidneys are filtering the blood and how well
kidney function? they are removing waste.
What is a normal GFR value? >90
What GFR value indicates an absolute need to start <15- this means that patient is in CKD stage 5
a patient on dialysis?
What is the second most important lab value to Creatinine
measure kidney function?
A waste product in the blood. If your kidneys are functioning properly, then this
What is creatinine? waste product is removed by your kidneys. When kidney function decreases, your
creatinine level starts to rise.
What is a normal creatine value? Around 1
Blood urea nitrogen is a normal waste product when your body breaks down urea.
Why is BUN least telling for kidney function?
However, this is not specific to the kidneys. It can also indicate liver issues.
What is a normal BUN level? 10-20
With which first-line BP medication do we want to ACE Inhibitors
check the BUN/Cr?
What finding on a UA id indicative of true kidney Casts- WBC or RBC casts always need to be referred out
damage?
When do we screen for microalbumin in the urine? We're always going to screen when DM and HTN is first diagnosed.
What are the most common causes of CKD? HTN and DM
Why is it important to perform early screening for Patients who have mild kidney damage do not have symptoms, this screening will
microalbumin in the urine? ideally identify damage early and prevent progression.
What stage of CKD do patients show true Stage 3 or worse
symptoms?
How often are we screening for micro albumin? Bare minimum is going to be annually for patients with DM or HTN or both.
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What is the normal range of microalbumin? < 30
What is the most common symptom of all anemias? Fatigue
12-18
What is a normal hemoglobin level?
Women are on the lower end, and men are on the higher end
3 to 1
What is a normal hemoglobin to hematocrit ratio?
36-54%
What does MCV stand for? mean corpuscular volume
What is a normal MCV? 80-100
What does low MCV indicate? Microcytic anemias
What is the most common microcytic anemia? Iron deficiency anemia
What is the biggest risk faction for the development The ingestion of cow's milk
of IDA is int he first year of life?
What does high MCV levels indicate? Microcytic anemia
What are the most common microcytic anemias? B12 and folate
What symptoms are common with B12 deficiency Neuro symptoms- the most common symptom is parasthesia
anemia?
What surgery typically leads to B12 deficiency Gastrectomy patients- who have part of their stomach removed
anemia?
In order for B12 to be absorbed, it needs to be able to combine with intrinsic
Why do gastrectomy patients typically have B12
factor, which is produced in the stomach. If we remove a large portion of the
deficiency anemia?
stomach then we lose a lot of that intrinsic factor.
What diabetes medication used long term can also Metformin
lead to B12 deficiency?
What is an abnormal lead level? >5, ideally no lead should be within the body
What kind of symptoms may lead intoxication lead Cognitive delays and behavioral problems
to?
LIT
Lead
What are the 3 microcytic anemias?
Iron
Thalassemia
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FAB
What are the 2 macrocytic anemias?
Folate and B12
Total cholesterol
HDl
What are the components of a lipid profile?
LDL
Triglycerides
What's a normal total cholesterol level? <200
What is a normal HDL level? 40-60, the higher the better
What is a normal LDL level? <100
What is a normal triglyceride level? <150
How often should you be ordering a standard Every 5 years unless they are having symptoms, risk factors, on treatment, etc.
limpid profile on a patient?
Bad cholesterol, it is our major culprit in atherosclerosis in clogging up those
What is LDL?
arteries.
Good cholesterol, it is cardio protective and helps remove excess cholesterol from
What is HDL?
the body.
What are some factors that impact our total Smoking, diet, weight, and physical activity
cholesterol?
What does triglycerides assist in assessing? Insulin resistance and your true dietary intake
If triglycerides get >500 then patient will be at really Pancreatitis
high risk for what?
What is the first line treatment for abnormal lipid HMG-CoA Reductase Inhibitors- Statin drugs
levels?
What if a patient is having increased muscle pain on Rhabdomyolysis
a statin, what is worst case scenario?
What lab value will assess for rhabdomyolysis? CK level
How high is a CK level going to be in rhabdo? 5 times the normal limit
What can rhabdomyolysis lead to? Renal failure
When a patient is on a statin, the kidney of concern, The liver
but what other organ is a concern as well?
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