tryCandCMolecularCDiagnostics,C
8thCEditionCbyCNaderCRifai,CPhDC
ChaptersC1C-C49C
,TietzCFundamentalsCofCClinicalCChemistryCandCMolecularCDiagnosticsC8thC EditionCTestCBank
TableCofCcontents:
I.CPrinciplesCOfCLaboratoryCMedicine
ChapterC1.CClinicalCChemistry,CMolecularCDiagnostics,CandCLaboratoryCMedicine
ChapterC2.CSelectionCandCAnalyticalCEvaluationCofCMethodsC—
CWithCStatisticalCTechniques
ChapterC3.CClinicalCEvaluationCofCMethods
ChapterC4.CEvidence-BasedCLaboratoryCMedicine
ChapterC5.CEstablishmentCandCUseCofCReferenceCValues
ChapterC6.CSpecimenCCollection,CProcessing,CandCOtherCPreanalyticalCVariables
ChapterC7.CQualityCManagement
II.CAnalyticalCTechniquesCAndCInstrumentation
ChapterC8.CPrinciplesCofCBasicCTechniquesCandCLaboratoryCSafety
ChapterC9.COpticalCTechniques
ChapterC10.CElectrochemistryCandCChemicalCSensors
ChapterC11.CElectrophoresis
ChapterC12.CChromatography
ChapterC13.CMassCSpectrometry
ChapterC14.CEnzymeCandCRateCAnalyses
ChapterC15.CImmunochemicalCTechniques
ChapterC16CAutomation
ChapterC17.CPoint-of-CareCInstrumentation
III.C Analytes
ChapterC18.CAminoCAcids,CPeptides,CandCProteins
ChapterC19.CSerumCEnzymes
ChapterC20.CTumorCMarkersCandCCancerCGenes
ChapterC21.CKidneyCFunctionCTestsC—CCreatinine,CGFR,CUrea,CandCUricCAcid
ChapterC22.CCarbohydrates
ChapterC23.CLipids,CLipoproteins,CApolipoproteins,CandCOtherCCardiacCRiskCFactors
ChapterC24.CElectrolytesCandCBloodCGases
ChapterC25.CHormones
ChapterC26.C CatecholaminesCandCSerotonin
ChapterC27.C Vitamins,CTraceCElements,CNutritionalCAssessment
ChapterC28.CHemoglobin,CIron,CandCBilirubin
ChapterC29.CPorphyrinsCandCPorphyrias
ChapterC30.CTherapeuticCDrugsCandCTheirCManagement
ChapterC31.CClinicalCToxicology
ChapterC32.C ToxicCMetals
IV.C Pathophysiology
ChapterC33.CDiabetes
,ChapterC34.C CardiovascularCDisease
ChapterC35.CKidneyCDisease
ChapterC36.C PhysiologyCandCDisordersCofCWater,CElectrolyte,CandCAcid-BaseCMetabolism
ChapterC37.CCLiverCDisease
ChapterC38.C GastrointestinalCandCPancreaticCDiseases
ChapterC39.CCDisordersCofCBoneCandCMineralCMetabolism
ChapterC40.CCDisordersCofCtheCPituitaryCGland
ChapterC41.C DisordersCofCtheCAdrenalCCortex
ChapterC42.C ThyroidCDisorders
ChapterC43.C Reproduction-RelatedCDisorders
ChapterC44.CCPregnancyCandCPrenatalCTesting
ChapterC45.C NewbornCScreeningCandCInbornCErrorsCofCMetabolism
ChapterC46.CPharmacogenetics
V.C MolecularCDiagnostics
ChapterC47.CPrinciplesCofCMolecularCBiology
ChapterC48.CNucleicCAcidCTechniquesCandCApplications
ChapterC49.CGenomesCandCNucleicCAcidCAlterations
, ChapterC01:CClinicalCChemistry,CMolecularCDiagnostics,CandCLaboratoryCMedicineCT
estCBank
MULTIPLECCHOICE
1. AnCindividualCworkingCinCaCclinicalCchemistryClaboratoryCisCmarriedCtoCaCsalesCrepre
sentativeCwhoCworksCforCaCcompanyCthatCsellsCchemistryClaboratoryCsupplies.CWhen
CtheClaboratoryCmanagerCrequestsCaClistCofCneededCsupplies,CcostCofCsupplies,CandC
vendors,CthisCindividualConlyCrecommendsCtheCspouse’sCcompanyCasCtheCvendor.CThis
CisCconsideredCtoCbeCa(n):
a. accountingCissue.
b. possibleCconflictCofCinterest.
c. maintenanceCofCconfidentialityCissue.
d. problemCwithCresourceCallocation.
ANS:CB
ConcernChasCbeenCraisedCoverCtheCinterrelationshipsCbetweenCpractitionersCinCtheCm
edicalCfieldCandCcommercialCsuppliersCofCdrugs,Cdevices,Cequipment,Cetc.,CtoCtheCme
dicalCprofession.
Similarly,CrelationshipsChaveCbeenCscrutinizedCbetweenCclinicalClaboratoriansCandCman
ufacturersCandCprovidersCofCdiagnosticCequipmentCandCsupplies.CTheseCconcernsCledCt
heCNationalCInstitutesCofCHealthC(NIH)CinC1995CtoCrequireCofficialCinstitutionalCreview
CofCfinancialCdisclosureCbyCresearchersCandCmanagementCofCsituationsCinCwhichCdisclo
sureCindicatesCpotentialCconflictsCofCinterest.
DIF: 1 REF:CCCPageC4-5 OBJ:C6C|C7
2. ACpatientCvisitsCherCphysicianCstatingCthatCherCprescribedCpainkillerCisCnotCworking
CtoCreduceCtheCpainCfollowingCherCrecentCsurgery.CACfriendCofCtheCpatientCclaimsC
thatCtheCsameCpainkillerC“workedCwonders”CtoCreduceCherCpainCafterCtheCsameCsur
gery.CTheCphysicianCstatesCthatCtheCdifferenceCinCtheCeffectCofCtheCdrugCmightCbe
CcausedCby
,CwhichCisCstudiedCinCpharmacogenetics.
a. epidemiology
b. anCinheritedCdisease
c. aCconflictCofCinterest
d. aCgeneticCvariationCinCdrug-metabolizingCenzymes
ANS:CD
PharmacogeneticsCisCtheCstudyCofCtheCgeneticCvariationCofCdrugCmetabolism
CbetweenCindividuals.
DIF: 1 REF:CCCPageC3 OBJ:C1
3. JohnCworksCinCaCmolecularCdiagnosticsClaboratoryCandCreceivesCaCbloodCsampleCth
atChasCtheCnameCofCaCcloseCfriendCprintedConCtheCbar-
codedClabel.CTheCgeneticCtestCthatCisCorderedConCtheCfriend’sCsampleCwouldCprovid
eCdiagnosticCinformationCaboutCaCdisorderCthatChasCaCpoorCprognosis,CandCtheCtes
tCisCusuallyCperformedCbyCJohn.CHeCasksCaCfellowCemployeeCtoCanalyzeCtheCsample
CforChimCandCnotCdivulgeCtheCresults.CThisCethicalCissueCconcerns:
a. confidentialityCofCpatientCgeneticCandCmedicalCinformation.
b. aCconflictCofCinterest.