NPB 101 L RENAL LAB QUESTIONS & ANSWERS
Functions of kidney - Answers -1) stimulates RBC synthesis with production of
erythropoeitin; 2)Water balance; 3) pH balance; 4) ion balance; 5) elimination of waste
via an aqueous solution
Components of renal corpuscle - Answers -Glomerular capillaries and Bowmna's
capsules
Starting with renal corpuscle, list components of renal tubule as they are encountered
by filtrate - Answers -Proximal convoluted tubule, descending limb of the Loop of
Henle, ascending limb of the Loop of Henle, Distal Convoluted tubules, Collecting Duct.
Describe effect of decreasing and increasing afferent arteriole radius on gloerular
capillary pressure and filtration rate - Answers -When the afferent arteriole
vasoconstricts, it reduces blood flow in to the glomerulus. This results in a decrease in
glomerularus capillary blood pressure, which would then reduce GFR.
Vice versa
Describe the effect of decreasing and increasing efferent arteriole radius on glomerular
capillary pressure and filtration rate. - Answers -Vasoconstriction of the efferent
arteriole reduces flow out of the glomerular capillaries. This raised the Pca and GFR.
If efferent arteriole dilates, blood would drain from glomerular capillaries and reduce
GFR
How did aldosterone affect urine volume? - Answers -We saw in the data a decrease in
urine production in the presence of aldosterone. This hormone promotes Na+
reabsorption at the distal convoluted tubule and subsequently an increase in water
reabsorption.
How did the addition of ADH affect urine volume? - Answers -ADH increases water
reabsorption across the DCT and Collecting Duct. You'd expect a decreased GFR and
urine volume in the presence of ADH. We saw a gigantic decrease in urine volume.
What is the principal determinant for the release of aldosterone from the adrenal cortex?
- Answers -a drop in Mean Arterial BP, a decrease in afferent arteriolar blood pressure
and a drop in DCT tubular NaCl content in the filtrate. In response to either stimuli, the
granular cells secret renin, which eventually leads to increased ALDO secretion.
How did the addition of both aldosterone and ADH affect urine volume? - Answers -
Compared to baseline GFR, urine production and urine concentration, addition of ADH
and ALDO decreased urine volume and raised urine concentration of dilute solute.
ALDO promoted reabsorption of NaCL and water, while ADH promoted water
reabsorption across the DCT and CD. This resulted in a low volume and concentrated
urine.
Functions of kidney - Answers -1) stimulates RBC synthesis with production of
erythropoeitin; 2)Water balance; 3) pH balance; 4) ion balance; 5) elimination of waste
via an aqueous solution
Components of renal corpuscle - Answers -Glomerular capillaries and Bowmna's
capsules
Starting with renal corpuscle, list components of renal tubule as they are encountered
by filtrate - Answers -Proximal convoluted tubule, descending limb of the Loop of
Henle, ascending limb of the Loop of Henle, Distal Convoluted tubules, Collecting Duct.
Describe effect of decreasing and increasing afferent arteriole radius on gloerular
capillary pressure and filtration rate - Answers -When the afferent arteriole
vasoconstricts, it reduces blood flow in to the glomerulus. This results in a decrease in
glomerularus capillary blood pressure, which would then reduce GFR.
Vice versa
Describe the effect of decreasing and increasing efferent arteriole radius on glomerular
capillary pressure and filtration rate. - Answers -Vasoconstriction of the efferent
arteriole reduces flow out of the glomerular capillaries. This raised the Pca and GFR.
If efferent arteriole dilates, blood would drain from glomerular capillaries and reduce
GFR
How did aldosterone affect urine volume? - Answers -We saw in the data a decrease in
urine production in the presence of aldosterone. This hormone promotes Na+
reabsorption at the distal convoluted tubule and subsequently an increase in water
reabsorption.
How did the addition of ADH affect urine volume? - Answers -ADH increases water
reabsorption across the DCT and Collecting Duct. You'd expect a decreased GFR and
urine volume in the presence of ADH. We saw a gigantic decrease in urine volume.
What is the principal determinant for the release of aldosterone from the adrenal cortex?
- Answers -a drop in Mean Arterial BP, a decrease in afferent arteriolar blood pressure
and a drop in DCT tubular NaCl content in the filtrate. In response to either stimuli, the
granular cells secret renin, which eventually leads to increased ALDO secretion.
How did the addition of both aldosterone and ADH affect urine volume? - Answers -
Compared to baseline GFR, urine production and urine concentration, addition of ADH
and ALDO decreased urine volume and raised urine concentration of dilute solute.
ALDO promoted reabsorption of NaCL and water, while ADH promoted water
reabsorption across the DCT and CD. This resulted in a low volume and concentrated
urine.
