MSN 611 - Pharm Final Exam Information Questions
With Correct Answers
Nursing |Fundamentals
IV |route |is |the |fastest
Pharmacokinetics
ADME
1. |Absorption: |how |medication |gains |access |to |the |body
2. |Distribution
3. |Metabolism
4. |Excretion
1st |pass |effect
When |a |drug |is |metabolized |at |a |specific |point |in |the |body, |resulting |in |a |lower |concentration |
of |the |active |substance. |
This |phenomenon |is |termed |the |first-pass |effect |and |is |most |often |described |in |the |context |of |
absorption |of |chemicals |following |ingestion. |In |general, |the |first-pass |effect |after |oral |
absorption |is |the |result |of |efficient |uptake |and |metabolism |of |compounds |by |the |liver.
Generic |vs |Brand
A |medication |only |has |ONE |generic |name |but |can |have |MULTIPLE |brand |names |(ex: |ibuprofen;
|MOTRIN/ADVIL)
When |should |a |patient |be |assessed |before |administering |a |medication?
The |patient |should |be |assessed |right |before |administration |of |a |drug |(ex: |assess |BP |prior |to |
administering |a |BP |med)
What |assessment |in |a |patient |needs |immediate |intervention?
Oliguria |or |anuria
NSAIDS
Nephrotoxic |& |Hepatotoxic |
, COX-1/COX-2 |inhibitors |with |the |exception |of |Celecoxib |
#1 |Adverse |Effect: |GI |bleeding |(fecal |occult |blood |test)
Acetaminophen
Hepatotoxic
Not |an |antiinflammatory
Corticosteroids
Different |routes--> |inhaled, |intranasal, |IM, |topical
Major |systemic |adverse |effects: |hyperglycemia, |HTN, |depressed |immune |function, |decreased |
bone |density |(for |these |reasons |we |do |NOT |like |to |administer |steroids |systemically)
What |reasons |are |steroids |used?
Asthma, |cancer, |nausea, |etc.
Serotonin |5-HT |Receptor |Agonists |(-triptans)
Work |to |treat |migraines
Migraines |are |most |common |in |females
These |medications |are |TERATOGENIC
Contraindicated |in |patients |with |cardiac |disease, |HTN, |or |taking |other |medications |such |as |
SSRIs/SNRIs
Opioids
Patients |should |not |be |on |more |than |one |opioid |medication |
Can |cause |bradypnea |and |hypotension |
Long-term |side |effect: |constipation
*Naloxone |is |used |to |reverse |OD
What |other |uses |do |opioids |have?
Cough |(codeine)
Diarrhea
SSRIs
With Correct Answers
Nursing |Fundamentals
IV |route |is |the |fastest
Pharmacokinetics
ADME
1. |Absorption: |how |medication |gains |access |to |the |body
2. |Distribution
3. |Metabolism
4. |Excretion
1st |pass |effect
When |a |drug |is |metabolized |at |a |specific |point |in |the |body, |resulting |in |a |lower |concentration |
of |the |active |substance. |
This |phenomenon |is |termed |the |first-pass |effect |and |is |most |often |described |in |the |context |of |
absorption |of |chemicals |following |ingestion. |In |general, |the |first-pass |effect |after |oral |
absorption |is |the |result |of |efficient |uptake |and |metabolism |of |compounds |by |the |liver.
Generic |vs |Brand
A |medication |only |has |ONE |generic |name |but |can |have |MULTIPLE |brand |names |(ex: |ibuprofen;
|MOTRIN/ADVIL)
When |should |a |patient |be |assessed |before |administering |a |medication?
The |patient |should |be |assessed |right |before |administration |of |a |drug |(ex: |assess |BP |prior |to |
administering |a |BP |med)
What |assessment |in |a |patient |needs |immediate |intervention?
Oliguria |or |anuria
NSAIDS
Nephrotoxic |& |Hepatotoxic |
, COX-1/COX-2 |inhibitors |with |the |exception |of |Celecoxib |
#1 |Adverse |Effect: |GI |bleeding |(fecal |occult |blood |test)
Acetaminophen
Hepatotoxic
Not |an |antiinflammatory
Corticosteroids
Different |routes--> |inhaled, |intranasal, |IM, |topical
Major |systemic |adverse |effects: |hyperglycemia, |HTN, |depressed |immune |function, |decreased |
bone |density |(for |these |reasons |we |do |NOT |like |to |administer |steroids |systemically)
What |reasons |are |steroids |used?
Asthma, |cancer, |nausea, |etc.
Serotonin |5-HT |Receptor |Agonists |(-triptans)
Work |to |treat |migraines
Migraines |are |most |common |in |females
These |medications |are |TERATOGENIC
Contraindicated |in |patients |with |cardiac |disease, |HTN, |or |taking |other |medications |such |as |
SSRIs/SNRIs
Opioids
Patients |should |not |be |on |more |than |one |opioid |medication |
Can |cause |bradypnea |and |hypotension |
Long-term |side |effect: |constipation
*Naloxone |is |used |to |reverse |OD
What |other |uses |do |opioids |have?
Cough |(codeine)
Diarrhea
SSRIs
