ANCC IQ Domains 1–5 Question Bank– Nursing
Informatics Certification | ANCC | Summer 2026 | Fully
answeredquestions with verified correct answers
.
Domain 1: ScientificFoundation(40 questionswithrationales)
As a PMHNP, you are aware of antipsychotic medication side effects. Which of the
followingsideeffectsof antipsychoticmedicationshas an insidious,delayed- onset
typically 1 to 2 years after initiation of the medication?
a. Dry mouth
b. Tardivedyskinesia
c. Sedation
d. Weightgain - B
In evaluatinga 4-year-old, onewouldexpectwhichof thefollowingdelaysin Asperger's
Disorder?
a. Languagedevelopment
b. Cognitivedevelopment
c. Motorskills coordination
d. Socialskills development- D
Which areaof thebrain has beenimplicatedto modulatepain and can helpexplain how
transcranial magnetic stimulation can help decrease pain?
a. Prefrontalcortex
b. Insula cortex
c. Dorsolateralprefrontalcortex
d. Anteriorcingulatecortex- A
Which of the following antidepressants is associated with-related
dose cardiovascular
adverseeffectswhichrequireadherenceto maximumrecommended dosing, unless
higher doses are deemed appropriate despite risks?
a. Citalopram(Celexa)
b. Venlafaxine(Effexor)
c. Mirtazapine(Remeron)
,d. Sertraline(Zoloft) - A
,Which of thefollowingfindings wouldraiseconcernin an annualsportsexamfor a 15-
year-old girl?
a. Scar tissuefrom hymenaltearat 11 o'clock(reportedbiking injury)
b. Bloodpressure86/56
c. Height 67 inches,weight102pounds
d. Pulse60, respirations26 - C
A week after raising the dose of risperidone (Risperdal), a patient treated for
schizophrenia presents to the clinic with reports of an acute change in mental status,
fever,and rigidity. As thetreatingPMHNP, you knowthesesymptomsare consistent
with which of the following?
a. Neurolepticmalignantsyndrome(NMS)
b. Anticholinergicwithdrawalsyndrome
c. Extrapyramidalsideeffects
d. Serotoninsyndrome- A
Which of thefollowingstatementsregardingdisulfiram(Antabuseis correct?
a. Disulfiram shouldnot be takenfor at least6 hoursafterdrinking alcohol.
b. Avoid anythingcontainingalcohol(i.e.,vinegar,mouthwash,aftershave,cough
medication) while using disulfiram and for 2 weeks after discontinuing.
c. A disulfiram-alcoholreactioncan occurup to 1 weekafterdiscontinuing
disulfiram.
d. Disulfiramcan lowerliver functiontestsso monitoringis necessary.- B
Which moodstabilizeris mostassociatedwitha potentiallylife-threateningrash?
a. Divalproex(Depakote)
b. Lamotrigine(Lamictal)
c. Lithium (Eskalith)
d. Carbamazepine(Tegretol)- B
Which of thefollowingstatementsmostaccuratelyreflectsthepredominantrisk factors
of antisocial personality disorders?
a. Gang affiliationand earlysubstanceabuse
b. Geneticpredispositionof first-degreefamilymember
, c. Childhoodabuseand traumafrom domesticviolence
d. Lowersocioeconomicstatusfrom single-parentfamilies- B
Informatics Certification | ANCC | Summer 2026 | Fully
answeredquestions with verified correct answers
.
Domain 1: ScientificFoundation(40 questionswithrationales)
As a PMHNP, you are aware of antipsychotic medication side effects. Which of the
followingsideeffectsof antipsychoticmedicationshas an insidious,delayed- onset
typically 1 to 2 years after initiation of the medication?
a. Dry mouth
b. Tardivedyskinesia
c. Sedation
d. Weightgain - B
In evaluatinga 4-year-old, onewouldexpectwhichof thefollowingdelaysin Asperger's
Disorder?
a. Languagedevelopment
b. Cognitivedevelopment
c. Motorskills coordination
d. Socialskills development- D
Which areaof thebrain has beenimplicatedto modulatepain and can helpexplain how
transcranial magnetic stimulation can help decrease pain?
a. Prefrontalcortex
b. Insula cortex
c. Dorsolateralprefrontalcortex
d. Anteriorcingulatecortex- A
Which of the following antidepressants is associated with-related
dose cardiovascular
adverseeffectswhichrequireadherenceto maximumrecommended dosing, unless
higher doses are deemed appropriate despite risks?
a. Citalopram(Celexa)
b. Venlafaxine(Effexor)
c. Mirtazapine(Remeron)
,d. Sertraline(Zoloft) - A
,Which of thefollowingfindings wouldraiseconcernin an annualsportsexamfor a 15-
year-old girl?
a. Scar tissuefrom hymenaltearat 11 o'clock(reportedbiking injury)
b. Bloodpressure86/56
c. Height 67 inches,weight102pounds
d. Pulse60, respirations26 - C
A week after raising the dose of risperidone (Risperdal), a patient treated for
schizophrenia presents to the clinic with reports of an acute change in mental status,
fever,and rigidity. As thetreatingPMHNP, you knowthesesymptomsare consistent
with which of the following?
a. Neurolepticmalignantsyndrome(NMS)
b. Anticholinergicwithdrawalsyndrome
c. Extrapyramidalsideeffects
d. Serotoninsyndrome- A
Which of thefollowingstatementsregardingdisulfiram(Antabuseis correct?
a. Disulfiram shouldnot be takenfor at least6 hoursafterdrinking alcohol.
b. Avoid anythingcontainingalcohol(i.e.,vinegar,mouthwash,aftershave,cough
medication) while using disulfiram and for 2 weeks after discontinuing.
c. A disulfiram-alcoholreactioncan occurup to 1 weekafterdiscontinuing
disulfiram.
d. Disulfiramcan lowerliver functiontestsso monitoringis necessary.- B
Which moodstabilizeris mostassociatedwitha potentiallylife-threateningrash?
a. Divalproex(Depakote)
b. Lamotrigine(Lamictal)
c. Lithium (Eskalith)
d. Carbamazepine(Tegretol)- B
Which of thefollowingstatementsmostaccuratelyreflectsthepredominantrisk factors
of antisocial personality disorders?
a. Gang affiliationand earlysubstanceabuse
b. Geneticpredispositionof first-degreefamilymember
, c. Childhoodabuseand traumafrom domesticviolence
d. Lowersocioeconomicstatusfrom single-parentfamilies- B
