NURS 615: ADVANCED
PHARMACOTHERAPEUTICS
MARYVILLE UNIVERSITY EXAM 4
WITH 100% CORRECT ANSWERS 2026
What is Tiotropium (SPIRIVA) used to treat? correct answers
>> Used in the management/ maintenance treatment of chronic
obstructive pulmonary disease (COPD) which includes chronic
bronchitis and emphysema.
What is the drug classification of Tiotropium? correct answers
>> >It is a long-acting, 24H anticholinergic-bronchodilator.
>It is a muscurinic receptor antagonist, often referred to as an
antimuscurinic or anticholinergic agent.
What is the mechanism of action of Tiotropium (SPIRIVA)
correct answers >> It does not display selectivity for specific
muscarinic receptors, when topically applied it acts mainly on M3
muscarinic receptors[8] located on smooth muscle cells and
submucosal glands. This leads to a reduction in smooth muscle
contraction and mucus secretion and thus produces a
bronchodilatory effect.
What are the adverse effects with montelukast (Singular)
correct answers >> Anxiety, aggression, depression, suicidal
thoughts,
, What patient teaching should accompany the prescription of
montelukast (Singulair)? correct answers >> Teach pt
regarding adverse effect about aggression , depression suicidal
thoughts that could occur
What patient teaching should be provided when prescribing
inhaled corticosteroids? correct answers >> They should be
taken 2x a day every day for the use of prevention of asthma.
Rinse mouth after use to prevent oral thrush.
What ethnic background should not be prescribed long-acting
beta agonists? correct answers >> African Americans,
increased incidence of death in this population
What medication would you prescribe for bronchospasm for a
patient taking propranolol? correct answers >> Ipratropium
What is the mechanism of action of albuterol? correct answers
>> Activation of beta adrenergic receptors lead to relaxation of
the muscle of the lung and opening and dilation of the airway
Beta adrenergic receptor are coupled with stimulatory g-protein
of the the d-anelyl cyclase> This enzyme produces the second
messennger cyclic AMP (in the lungs it cAMP decreases calcium
concentration w/in cells and and activates protein kinase A. Both
of these inactivates myosin activase kinase and myosin like
phosphatase
They open large conductants of hyperpolarize airway smooth
muscle cells
PHARMACOTHERAPEUTICS
MARYVILLE UNIVERSITY EXAM 4
WITH 100% CORRECT ANSWERS 2026
What is Tiotropium (SPIRIVA) used to treat? correct answers
>> Used in the management/ maintenance treatment of chronic
obstructive pulmonary disease (COPD) which includes chronic
bronchitis and emphysema.
What is the drug classification of Tiotropium? correct answers
>> >It is a long-acting, 24H anticholinergic-bronchodilator.
>It is a muscurinic receptor antagonist, often referred to as an
antimuscurinic or anticholinergic agent.
What is the mechanism of action of Tiotropium (SPIRIVA)
correct answers >> It does not display selectivity for specific
muscarinic receptors, when topically applied it acts mainly on M3
muscarinic receptors[8] located on smooth muscle cells and
submucosal glands. This leads to a reduction in smooth muscle
contraction and mucus secretion and thus produces a
bronchodilatory effect.
What are the adverse effects with montelukast (Singular)
correct answers >> Anxiety, aggression, depression, suicidal
thoughts,
, What patient teaching should accompany the prescription of
montelukast (Singulair)? correct answers >> Teach pt
regarding adverse effect about aggression , depression suicidal
thoughts that could occur
What patient teaching should be provided when prescribing
inhaled corticosteroids? correct answers >> They should be
taken 2x a day every day for the use of prevention of asthma.
Rinse mouth after use to prevent oral thrush.
What ethnic background should not be prescribed long-acting
beta agonists? correct answers >> African Americans,
increased incidence of death in this population
What medication would you prescribe for bronchospasm for a
patient taking propranolol? correct answers >> Ipratropium
What is the mechanism of action of albuterol? correct answers
>> Activation of beta adrenergic receptors lead to relaxation of
the muscle of the lung and opening and dilation of the airway
Beta adrenergic receptor are coupled with stimulatory g-protein
of the the d-anelyl cyclase> This enzyme produces the second
messennger cyclic AMP (in the lungs it cAMP decreases calcium
concentration w/in cells and and activates protein kinase A. Both
of these inactivates myosin activase kinase and myosin like
phosphatase
They open large conductants of hyperpolarize airway smooth
muscle cells
