NR 293 Exam 3 Study Guide final- Study Guide for NR 293 Exam 3 Final.

Study Guide for NR 293 Exam 3 • Alpha2-adrenergic receptor stimulators (agonists)/clonidine o Stimulate alpha2-adrenergic receptors in the brain o Decrease sympathetic outflow from the CNS, decrease norepinephrine production o Stimulates alpha2-adrenergi receptors, thus reducing renin o Examples: Clonidine (Catapres), Methyldopa (aldomet): used for pregnant women w/htn • Alpha1-blockers/”azosin,” o Block alpha1-adrenergic receptors o Management of severe heart failure (HF) when used with cardiac glycosides and diuretics o Some used to relieve symptoms of BPH- increase urinary flow rate o Example: “ Azosin” (doxazosin (Cardura) o Adverse Effects:  Serious: hypotension (first dose) syncope  Common: dizziness o Nursing implications: instruct pt. to lie down after taking first dose because they may become dizzy • Beta-blockers “olol”: First-line treatment for heart failure & HTN o Reduce BP by reducing heart rate through beta1 blockade (block receptors for norepinhrine) o Cause reduced secretion of renin o Long-term use causes reduced peripheral vascular resistance o Adverse Effects: orthostatic hypotension, bradycardia w/ reflex tachycardia, sexual dysfunction in men, possible hypoglycemia or hyperglycemia