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2019v1.0
i
, BRIEF CONTENTS
PART 1 Pharmacology Basics, 1 33 A drenal Drugs, 518
34 W omen’s Health Drugs, 528
1 T he Nursing Process and Drug Therapy, 1 35 Men’s Health Drugs, 548
2 Pharmacologic Principles, 13
3 Lifespan Considerations, 33
4 Cultural, Legal, and Ethical Considerations, 46 PART 6 Drugs Affecting the Respiratory System, 557
5 Medication Errors: Preventing and Responding, 60 36 A ntihistamines, Decongestants, Antitussives, and
6 Patient Education and Drug Therapy, 72 Expectorants, 557
7 Over-the-Counter Drugs and Herbal and Dietary 37 Respiratory Drugs, 570
Supplements, 84
8 Gene Therapy and Pharmacogenomics, 94
9 Photo Atlas of Drug Administration, 102 PART 7 Antiinfective and Antiinflammatory
Drugs, 589
PART 2 Drugs Affecting the Central Nervous 38 Antibiotics Part 1, 589
System, 135 39 Antibiotics Part 2, 614
40 Antiviral Drugs, 631
10 A nalgesic Drugs, 135 41 Antitubercular Drugs, 651
11 G eneral and Local Anesthetics, 165 42 Antifungal Drugs, 662
12 Central Nervous System Depressants and Muscle 43 Antimalarial, Antiprotozoal, and Anthelmintic Drugs, 671
Relaxants, 183 44 Antiinflammatory and Antigout Drugs, 684
13 Central Nervous System Stimulants and Related
Drugs, 198
14 Antiepileptic Drugs, 214 PART 8 Chemotherapeutic Drugs and Biologic and
15 Antiparkinson Drugs, 231 Immune Modifiers, 700
16 Psychotherapeutic Drugs, 247
17 Substance Use Disorder, 274 45 A ntineoplastic Drugs Part 1: Cancer Overview and Cell
Cycle–Specific Drugs, 700
46 Antineoplastic Drugs Part 2: Cell Cycle–Nonspecific and
PART 3 Drugs Affecting the Autonomic Nervous Miscellaneous Drugs, 726
System, 289 47 Biologic Response–Modifying and Antirheumatic
Drugs, 739
18 Adrenergic Drugs, 289 48 Immunosuppressant Drugs, 761
19 Adrenergic-Blocking Drugs, 303 49 Immunizing Drugs, 773
20 Cholinergic Drugs, 315
21 Cholinergic-Blocking Drugs, 326
PART 9 Drugs Affecting the Gastrointestinal
PART 4 Drugs Affecting the Cardiovascular and System and Nutrition, 788
Renal Systems, 335 50 Acid-Controlling Drugs, 788
51 Bowel Disorder Drugs, 801
22 Antihypertensive Drugs, 335 52 Antiemetic and Antinausea Drugs, 815
23 Antianginal Drugs, 356 53 Vitamins and Minerals, 827
24 Heart Failure Drugs, 370 54 Anemia Drugs, 848
25 Antidysrhythmic Drugs, 383 55 Nutritional Supplements, 858
26 Coagulation Modifier Drugs, 405
27 Antilipemic Drugs, 430
28 Diuretic Drugs, 445 PART 10 Dermatologic, Ophthalmic, and Otic
29 Fluids and Electrolytes, 458 Drugs, 869
ermatologic Drugs, 869
56 D
PART 5 Drugs Affecting the Endocrine and 57 O phthalmic Drugs, 885
Reproductive Systems, 475 58 O tic Drugs, 907
30 P ituitary Drugs, 475 Appendix: Pharmaceutical Abbreviations, 913
31 T hyroid and Antithyroid Drugs, 483 Answers to Review Questions, 914
32 Diabetes Drugs, 492 Index, 916
, A B O U T T H E AU T H O R S
Linda Lane Lilley, RN, PhD Clinical Pharmacy Services at Mobile Infirmary Medical Center. After
Linda Lilley received her diploma from moving to Chesapeake, Virginia, she served as the Clinical Pharmacy
Norfolk General School of Nursing, BSN Specialist/Coordinator of Clinical Pharmacy Services at Chesapeake
from the University of Virginia, Master Regional Medical Center in Chesapeake, Virginia for 19 years. Her
of Science (Nursing) from Old Dominion practice focused on developing and implementing clinical pharmacy
University, and PhD in Nursing from services as well as medication safety and The Joint Commission medi-
George Mason University. As an Associate cation management standards and national patient safety goals. She is
Professor Emeritus and University president of Drug Information Consultants, a business offering consul-
Professor at Old Dominion University, her tation and expert witness review for attorneys on medical malpractice
teaching experience in nursing education cases. She holds certifications in Medication Therapy Management,
spans over 25 years, including almost 20 Anticoagulation Management, and Immunizations. Shelly was awarded
years at Old Dominion. Linda’s teaching the Clinical Pharmacist of the Year Award in 2007 from the Virginia
expertise includes drug therapy and the nursing process, adult nurs- Society of Healthsystem Pharmacists. She led a multidisciplinary team
ing, physical assessment, fundamentals in nursing, oncology nursing, that won the Clinical Achievement of the Year Award from George
nursing theory, and trends in health care. The awarding of the univer- Mason University School of Public Health in 2007 for promoting safety
sity’s most prestigious title of University Professor reflects her teaching with narcotics in patients with sleep apnea; this program has also
excellence as a tenured faculty member. She has also been a two-time received national recognition. She was awarded the Service Excellence
university nominee for the State Council of Higher Education in Award from Chesapeake Regional Medical Center. Shelly’s professional
Virginia award for excellence in teaching, service, and scholarship. affiliations include the American Society of Healthsystem Pharmacists,
Linda received the 2012 Distinguished Nursing Alumni Award from the Virginia Society of Healthsystem Pharmacists, and the American
Old Dominion University School of Nursing for her “continued work Pharmacists Association. She is also the author of several editions of
on the successful pharmacology textbook published by Elsevier” and Elsevier’s 2022 Intravenous Medications: A Handbook for Nurses and
to recognize her “extraordinary work and the impact [the book] has Health Professionals.
had on baccalaureate education.” While at Old Dominion University,
Linda mentored and taught undergraduate and graduate students as
well as registered nurses returning for their BSN. Linda authored the
Julie S. Snyder, MSN, RN-BC
Julie Snyder received her diploma from
MED ERRORS column for the American Journal of Nursing between
Norfolk General Hospital School of Nursing
1994 and 1999, as well as numerous other peer-reviewed, published
and her BSN and MSN from Old Dominion
articles in professional nursing journals. Since retiring in 2005, Linda
University. After working in medical-sur-
continues to be active in nursing, serving as a member on dissertation
gical nursing, she worked in nursing staff
committees with the College of Health Sciences and maintaining mem-
development and community education.
bership in numerous professional and academic organizations. Dr.
Later, she transferred to the academic setting
Lilley continues to serve on the volunteer review panel for the monthly
and taught fundamentals of nursing, phar-
newsletter publication Nurse Advise-ERR (ISMP affiliated; the ISMP
macology, physical assessment, and adult
[Institute for Safe Medication Practices] is a nonprofit organization
medical-surgical nursing at a university
educating the healthcare community and consumers about safe medi-
school of nursing. Julie has recently worked
cation practices). Linda has served as a consultant to the school nurses
as a Quality Initiative Coordinator and a Clinical Nurse Educator in a
in the city of Virginia Beach and as a member on the City of Virginia
local hospital. She is now a visiting professor for the College of Nursing
Beach’s Health Advisory Board. She served as an appointed member on
at Chamberlain University. She has been certified by the ANCC in
the national advisory panel on medication error prevention with the
Nursing Continuing Education and Staff Development and currently
U.S. Pharmacopeia in Rockville, Maryland. She continues to educate
holds ANCC certification in Medical-Surgical Nursing. She is a mem-
nursing students and professional nurses about drug therapy and the
ber of Sigma Theta Tau International and was inducted into Phi Kappa
nursing process and speaks on the topics of drug therapy, safe medica-
Phi as Outstanding Alumni for Old Dominion University. She has
tion use, humor and healing, and grief and loss.
worked for Elsevier as a reviewer, ancillary writer, and author since
1997. She is coauthor of Elsevier’s Clinical Reasoning Cases in Nursing
Shelly Rainforth Collins, PharmD, with Dr. Mariann Harding. Julie’s professional service has included
serving on the Virginia Nurses’ Association Continuing Education
BCGP Committee, serving as Educational Development Committee chair for
Shelly Rainforth Collins is a Board-
the Epsilon Chi chapter of Sigma Theta Tau, serving as an item writer
Certified Geriatric Pharmacist and received
for the ANCC, working with a regional hospital educators’ group, and
her Doctor of Pharmacy degree from
serving as a consultant on various projects for local hospital education
the University of Nebraska, College of
departments. In addition, she has conducted pharmacology review
Pharmacy in 1985, with High Distinction.
classes for recent nursing graduates.
She then completed a clinical pharmacy
residency at Memorial Medical Center of
Long Beach in Long Beach, California. She worked as a pediatric clini-
cal pharmacist (neonatal specialist) at Memorial Medical Center before
moving to Mobile, Alabama, where she was the Assistant Director of
MORE THAN
A TEXTBOOK!
Enhance your learning with Evolve Student Resources.
These online study tools and exercises can help deepen your
understanding of textbook content so you can be more
prepared for class, perform better on exams, and succeed
in your course.
Activate the complete learning experience that comes with each
http://evolve.elsevier.com/Lilley
If your school uses its own Learning Management System, your resources may be
delivered on that platform. Consult with your instructor.
has already been revealed, the code may have been used and cannot
be re-used for registration. To purchase a new code to access these
Place
valuable study resources, simply follow the link above.
Sticker
Here
REGISTER TODAY!
You can now purchase Elsevier products on Evolve!
Go to evolve.elsevier.com/shop to search and browse for products.
2019v1.0
i
, BRIEF CONTENTS
PART 1 Pharmacology Basics, 1 33 A drenal Drugs, 518
34 W omen’s Health Drugs, 528
1 T he Nursing Process and Drug Therapy, 1 35 Men’s Health Drugs, 548
2 Pharmacologic Principles, 13
3 Lifespan Considerations, 33
4 Cultural, Legal, and Ethical Considerations, 46 PART 6 Drugs Affecting the Respiratory System, 557
5 Medication Errors: Preventing and Responding, 60 36 A ntihistamines, Decongestants, Antitussives, and
6 Patient Education and Drug Therapy, 72 Expectorants, 557
7 Over-the-Counter Drugs and Herbal and Dietary 37 Respiratory Drugs, 570
Supplements, 84
8 Gene Therapy and Pharmacogenomics, 94
9 Photo Atlas of Drug Administration, 102 PART 7 Antiinfective and Antiinflammatory
Drugs, 589
PART 2 Drugs Affecting the Central Nervous 38 Antibiotics Part 1, 589
System, 135 39 Antibiotics Part 2, 614
40 Antiviral Drugs, 631
10 A nalgesic Drugs, 135 41 Antitubercular Drugs, 651
11 G eneral and Local Anesthetics, 165 42 Antifungal Drugs, 662
12 Central Nervous System Depressants and Muscle 43 Antimalarial, Antiprotozoal, and Anthelmintic Drugs, 671
Relaxants, 183 44 Antiinflammatory and Antigout Drugs, 684
13 Central Nervous System Stimulants and Related
Drugs, 198
14 Antiepileptic Drugs, 214 PART 8 Chemotherapeutic Drugs and Biologic and
15 Antiparkinson Drugs, 231 Immune Modifiers, 700
16 Psychotherapeutic Drugs, 247
17 Substance Use Disorder, 274 45 A ntineoplastic Drugs Part 1: Cancer Overview and Cell
Cycle–Specific Drugs, 700
46 Antineoplastic Drugs Part 2: Cell Cycle–Nonspecific and
PART 3 Drugs Affecting the Autonomic Nervous Miscellaneous Drugs, 726
System, 289 47 Biologic Response–Modifying and Antirheumatic
Drugs, 739
18 Adrenergic Drugs, 289 48 Immunosuppressant Drugs, 761
19 Adrenergic-Blocking Drugs, 303 49 Immunizing Drugs, 773
20 Cholinergic Drugs, 315
21 Cholinergic-Blocking Drugs, 326
PART 9 Drugs Affecting the Gastrointestinal
PART 4 Drugs Affecting the Cardiovascular and System and Nutrition, 788
Renal Systems, 335 50 Acid-Controlling Drugs, 788
51 Bowel Disorder Drugs, 801
22 Antihypertensive Drugs, 335 52 Antiemetic and Antinausea Drugs, 815
23 Antianginal Drugs, 356 53 Vitamins and Minerals, 827
24 Heart Failure Drugs, 370 54 Anemia Drugs, 848
25 Antidysrhythmic Drugs, 383 55 Nutritional Supplements, 858
26 Coagulation Modifier Drugs, 405
27 Antilipemic Drugs, 430
28 Diuretic Drugs, 445 PART 10 Dermatologic, Ophthalmic, and Otic
29 Fluids and Electrolytes, 458 Drugs, 869
ermatologic Drugs, 869
56 D
PART 5 Drugs Affecting the Endocrine and 57 O phthalmic Drugs, 885
Reproductive Systems, 475 58 O tic Drugs, 907
30 P ituitary Drugs, 475 Appendix: Pharmaceutical Abbreviations, 913
31 T hyroid and Antithyroid Drugs, 483 Answers to Review Questions, 914
32 Diabetes Drugs, 492 Index, 916
, A B O U T T H E AU T H O R S
Linda Lane Lilley, RN, PhD Clinical Pharmacy Services at Mobile Infirmary Medical Center. After
Linda Lilley received her diploma from moving to Chesapeake, Virginia, she served as the Clinical Pharmacy
Norfolk General School of Nursing, BSN Specialist/Coordinator of Clinical Pharmacy Services at Chesapeake
from the University of Virginia, Master Regional Medical Center in Chesapeake, Virginia for 19 years. Her
of Science (Nursing) from Old Dominion practice focused on developing and implementing clinical pharmacy
University, and PhD in Nursing from services as well as medication safety and The Joint Commission medi-
George Mason University. As an Associate cation management standards and national patient safety goals. She is
Professor Emeritus and University president of Drug Information Consultants, a business offering consul-
Professor at Old Dominion University, her tation and expert witness review for attorneys on medical malpractice
teaching experience in nursing education cases. She holds certifications in Medication Therapy Management,
spans over 25 years, including almost 20 Anticoagulation Management, and Immunizations. Shelly was awarded
years at Old Dominion. Linda’s teaching the Clinical Pharmacist of the Year Award in 2007 from the Virginia
expertise includes drug therapy and the nursing process, adult nurs- Society of Healthsystem Pharmacists. She led a multidisciplinary team
ing, physical assessment, fundamentals in nursing, oncology nursing, that won the Clinical Achievement of the Year Award from George
nursing theory, and trends in health care. The awarding of the univer- Mason University School of Public Health in 2007 for promoting safety
sity’s most prestigious title of University Professor reflects her teaching with narcotics in patients with sleep apnea; this program has also
excellence as a tenured faculty member. She has also been a two-time received national recognition. She was awarded the Service Excellence
university nominee for the State Council of Higher Education in Award from Chesapeake Regional Medical Center. Shelly’s professional
Virginia award for excellence in teaching, service, and scholarship. affiliations include the American Society of Healthsystem Pharmacists,
Linda received the 2012 Distinguished Nursing Alumni Award from the Virginia Society of Healthsystem Pharmacists, and the American
Old Dominion University School of Nursing for her “continued work Pharmacists Association. She is also the author of several editions of
on the successful pharmacology textbook published by Elsevier” and Elsevier’s 2022 Intravenous Medications: A Handbook for Nurses and
to recognize her “extraordinary work and the impact [the book] has Health Professionals.
had on baccalaureate education.” While at Old Dominion University,
Linda mentored and taught undergraduate and graduate students as
well as registered nurses returning for their BSN. Linda authored the
Julie S. Snyder, MSN, RN-BC
Julie Snyder received her diploma from
MED ERRORS column for the American Journal of Nursing between
Norfolk General Hospital School of Nursing
1994 and 1999, as well as numerous other peer-reviewed, published
and her BSN and MSN from Old Dominion
articles in professional nursing journals. Since retiring in 2005, Linda
University. After working in medical-sur-
continues to be active in nursing, serving as a member on dissertation
gical nursing, she worked in nursing staff
committees with the College of Health Sciences and maintaining mem-
development and community education.
bership in numerous professional and academic organizations. Dr.
Later, she transferred to the academic setting
Lilley continues to serve on the volunteer review panel for the monthly
and taught fundamentals of nursing, phar-
newsletter publication Nurse Advise-ERR (ISMP affiliated; the ISMP
macology, physical assessment, and adult
[Institute for Safe Medication Practices] is a nonprofit organization
medical-surgical nursing at a university
educating the healthcare community and consumers about safe medi-
school of nursing. Julie has recently worked
cation practices). Linda has served as a consultant to the school nurses
as a Quality Initiative Coordinator and a Clinical Nurse Educator in a
in the city of Virginia Beach and as a member on the City of Virginia
local hospital. She is now a visiting professor for the College of Nursing
Beach’s Health Advisory Board. She served as an appointed member on
at Chamberlain University. She has been certified by the ANCC in
the national advisory panel on medication error prevention with the
Nursing Continuing Education and Staff Development and currently
U.S. Pharmacopeia in Rockville, Maryland. She continues to educate
holds ANCC certification in Medical-Surgical Nursing. She is a mem-
nursing students and professional nurses about drug therapy and the
ber of Sigma Theta Tau International and was inducted into Phi Kappa
nursing process and speaks on the topics of drug therapy, safe medica-
Phi as Outstanding Alumni for Old Dominion University. She has
tion use, humor and healing, and grief and loss.
worked for Elsevier as a reviewer, ancillary writer, and author since
1997. She is coauthor of Elsevier’s Clinical Reasoning Cases in Nursing
Shelly Rainforth Collins, PharmD, with Dr. Mariann Harding. Julie’s professional service has included
serving on the Virginia Nurses’ Association Continuing Education
BCGP Committee, serving as Educational Development Committee chair for
Shelly Rainforth Collins is a Board-
the Epsilon Chi chapter of Sigma Theta Tau, serving as an item writer
Certified Geriatric Pharmacist and received
for the ANCC, working with a regional hospital educators’ group, and
her Doctor of Pharmacy degree from
serving as a consultant on various projects for local hospital education
the University of Nebraska, College of
departments. In addition, she has conducted pharmacology review
Pharmacy in 1985, with High Distinction.
classes for recent nursing graduates.
She then completed a clinical pharmacy
residency at Memorial Medical Center of
Long Beach in Long Beach, California. She worked as a pediatric clini-
cal pharmacist (neonatal specialist) at Memorial Medical Center before
moving to Mobile, Alabama, where she was the Assistant Director of
