AAB MT HEMATOLOGY EXAM SCRIPT 2026
PRACTICE QUESTIONS WITH COMPLETE
SOLUTIONS VERIFIED 100% CORRECT
⩥ What disorder does a defect in heme synthesis lead to?
A. hemoglobinopathy
B. coagulopathy
C. thalassemia
D. porphyria. Answer: D. porphyria
⩥ What is the function of the enzyme methemoglobin-cytochrome C
reductase in red blood cell?
A. to keep iron in the ferric state
B. to keep iron in the ferrous state
C. to maintain an anaerobic pathway for glycolysis
D. to maintain an aerobic pathway for the Krebs cycle. Answer: B. to
keep iron in the ferrous state
⩥ Which hemoglobin has a 200 times greater binding capacity for the
hemoglobin molecule than oxygen?
,A. carboxyhemoglobin
B. oxyhemoglobin
C. sulfhemoglobin
D. methemoglobin. Answer: A. carboxyhemoglobin
⩥ What product is formed when ferrous iron of hemoglobin is oxidized
to the ferric state?
A. sulfhemoglobin
B. methemoglobin
C. carboxyhemoglobin
D. cyanmethemoglobin. Answer: B. methemoglobin
⩥ Which hemoglobin derivative causes irreversible changes in the red
blood cells?
A. sulfhemoglobin
B. methemoglobin
C. carboxyhemoglobin
D. cyanmethemoglobin. Answer: A. sulfhemoglobin
,⩥ Which of the following hemoglobin is NOT normally present in a
normal adult?
A. Hb-A1
B. Hb-A
C. Hb-S
D. Hb-F. Answer: C. Hb-S
⩥ Which embryonic hemoglobin is normally found in newborns?
A. Hb-F
B. Hb-Gower1
C. Hb-Gower2
D. Hb-Portland. Answer: A. Hb-F
⩥ What is the most abundant hemoglobin in a newborn?
A. Hb-Gower
B. Hb-A1
C. Hb-A2
D. Hb-F. Answer: D. Hb-F
, ⩥ What is the molecular structure of hemoglobin S?
A. valine replaces glutamic acid in the 6th position of the beta chain
B. lysine replaces glutamic acid in the 6th position of the beta chain
C. lysine replaces glutamine in the 26th position of the beta chain
D. valine replaces glutamine in the 26th position of the beta chain.
Answer: A. valine replaces glutamic acid in the 6th position of the beta
chain
⩥ Which of the following hemoglobin is insoluble under lowered
oxygen tension?
A. Hb-A
B. Hb-S
C. Hb-C
D. Hb-F. Answer: B. Hb-S
⩥ What laboratory test is used to confirm the specific diagnosis of sickle
cell anemia?
A. solubility test
B. sodium metabisulfite test
C. hemoglobin electrophoresis
PRACTICE QUESTIONS WITH COMPLETE
SOLUTIONS VERIFIED 100% CORRECT
⩥ What disorder does a defect in heme synthesis lead to?
A. hemoglobinopathy
B. coagulopathy
C. thalassemia
D. porphyria. Answer: D. porphyria
⩥ What is the function of the enzyme methemoglobin-cytochrome C
reductase in red blood cell?
A. to keep iron in the ferric state
B. to keep iron in the ferrous state
C. to maintain an anaerobic pathway for glycolysis
D. to maintain an aerobic pathway for the Krebs cycle. Answer: B. to
keep iron in the ferrous state
⩥ Which hemoglobin has a 200 times greater binding capacity for the
hemoglobin molecule than oxygen?
,A. carboxyhemoglobin
B. oxyhemoglobin
C. sulfhemoglobin
D. methemoglobin. Answer: A. carboxyhemoglobin
⩥ What product is formed when ferrous iron of hemoglobin is oxidized
to the ferric state?
A. sulfhemoglobin
B. methemoglobin
C. carboxyhemoglobin
D. cyanmethemoglobin. Answer: B. methemoglobin
⩥ Which hemoglobin derivative causes irreversible changes in the red
blood cells?
A. sulfhemoglobin
B. methemoglobin
C. carboxyhemoglobin
D. cyanmethemoglobin. Answer: A. sulfhemoglobin
,⩥ Which of the following hemoglobin is NOT normally present in a
normal adult?
A. Hb-A1
B. Hb-A
C. Hb-S
D. Hb-F. Answer: C. Hb-S
⩥ Which embryonic hemoglobin is normally found in newborns?
A. Hb-F
B. Hb-Gower1
C. Hb-Gower2
D. Hb-Portland. Answer: A. Hb-F
⩥ What is the most abundant hemoglobin in a newborn?
A. Hb-Gower
B. Hb-A1
C. Hb-A2
D. Hb-F. Answer: D. Hb-F
, ⩥ What is the molecular structure of hemoglobin S?
A. valine replaces glutamic acid in the 6th position of the beta chain
B. lysine replaces glutamic acid in the 6th position of the beta chain
C. lysine replaces glutamine in the 26th position of the beta chain
D. valine replaces glutamine in the 26th position of the beta chain.
Answer: A. valine replaces glutamic acid in the 6th position of the beta
chain
⩥ Which of the following hemoglobin is insoluble under lowered
oxygen tension?
A. Hb-A
B. Hb-S
C. Hb-C
D. Hb-F. Answer: B. Hb-S
⩥ What laboratory test is used to confirm the specific diagnosis of sickle
cell anemia?
A. solubility test
B. sodium metabisulfite test
C. hemoglobin electrophoresis
