,ChapterAD1ADChemicalADneurotransmission
Stahl:ADStahl'sADEssentialADPsychopharmacology:ADNeuroscientificADBasisADandADPracticalADAp
plicationsAD5thADEdition
MULTIPLEADCHOICE
1. AADpatientADwithADdepressionADmentionsADtoADtheADnurse,ADMyADmotherADsaysADd
epressionADisADaADchemicalADdisorder.ADWhatADdoesADsheADmean?ADTheADnursesADres
ponseADisADbasedADonADtheADtheoryADthatADdepressionADprimarilyADinvolvesADwhichAD
ofADtheADfollowingADneurotransmitters?
a. CortisolADandADGABA
b. COMTADandADglutamate
c. MonamineADandADglycine
d. SerotoninADandADnorepinephrine
ANS:ADD
OneADpossibleADcauseADofADdepressionADisADthoughtADtoADinvolveADoneADorADmoreADneur
otransmitters.ADSerotoninADandADnorepinephrineADhaveADbeenADfoundADtoADbeADimport
antADinADtheADregulationADofADdepression.ADThereADisADnoADresearchADtoADsupportADthat
ADtheADotherADoptionsADplayADaADsignificantADroleADinADtheADdevelopmentADofADdepress
ion.
2. AADpatientADhasADexperiencedADaADstrokeAD(cerebralADvascularADaccident)ADthatADha
sADresultedADinADdamageADtoADtheADBrocaADarea.ADWhichADevaluationADdoesADtheADnur
seADconductADtoADreinforceADthisADdiagnosis?
a. ObservingADtheADpatientADpickADupADaADspoon
b. AskingADtheADpatientADtoADreciteADtheADalphabet
c. MonitoringADtheADpatientsADbloodADpressure
d. ComparingADtheADpatientsADgripADstrengthADinADbothADhands
ANS:ADB
AccidentsADorADstrokesADthatADdamageADBrocasADareaADmayADresultADinADtheADinabilityA
DtoADspeakAD(i.e.,ADmotorADaphasia).ADFineADmotorADskills,ADbloodADpressureADcontrol,A
DandADmuscleADstrengthADareADnotADcontrolledADbyADtheADBrocaADareaADofADtheADleftADf
rontalADlobe.
3. TheADpatientADdiagnosedADwithADschizophreniaADasksADwhyADpsychotropicADmedic
ationsADareADalwaysADprescribedADbyADtheADdoctor.ADTheADnursesADanswerADwillADbeADb
asedADonADinformationADthatADtheADtherapeuticADactionADofADpsychotropicADdrugsADisA
Dthe
a.ADresult
TheADADoftemporal
ADtheirADAD
effect ADon:
lobe;AD especiallyADWernickesADarea
b. DendritesADandADtheirADabilityADtoADtransmitADelectricalADimpulses
c. TheADregulationADofADneurotransmittersADespeciallyADdopamine
d. TheADperipheralADnervousADsystemADsensitivityADtoADtheADpsychotropicADmedication
s
,ANS:ADC
MedicationsADusedADtoADtreatADpsychiatricADdisordersADoperateADinADandADaroundADtheAD
synapticADcleftADandADhaveADactionADatADtheADneurotransmitterADlevel,ADespeciallyADinA
DtheADcaseADofADschizophrenia,ADonADdopamine.ADTheADWernickesADarea,ADdendriteADfu
nction,ADorADtheADsensitivityADofADtheADperipheralADnervousADsystemADareADnotADreleva
ntADtoADeitherADschizophreniaADorADpsychotropicADmedications.
4. AADstudentADnurseADmuttersADthatADitADseemsADentirelyADunnecessaryADtoADhaveADtoA
DstruggleADwithADunderstandingADtheADanatomyADandADphysiologyADofADtheADneurolo
gicADsystem.ADTheADmentorADwouldADbaseADaADresponseADonADtheADunderstandingADt
hatADitADis:
NecessaryADbutADgenerallyADforADpsychiatricADnursesADwhoADfocusADprimarilyAD
a. onADbehavioralADinterventions
AADcomplexADundertakingADthatADadvanceADpracticeADpsychiatricADnursesADfreq
b. uentlyADuseADinADtheirADpractice
ImportantADprimarilyADforADtheADnursingADassessmentADofADpatientsADwithADbrainADt
c. raumacausedADcognitiveADsymptoms
NecessaryADforADplanningADpsychiatricADcareADforADallADpatientsADespeciallyADthose
d. ADexperiencingADpsychiatricADdisorders
ANS:ADD
NursesADmustADunderstandADthatADmanyADsymptomsADofADpsychiatricADdisordersADhav
eADaADneurologicADbasis,ADalthoughADtheADsymptomsADareADmanifestedADbehaviorally.A
DThisADunderstandingADfacilitatesADeffectiveADcareADplanning.ADTheADfoundationADofADk
nowledgeADisADnotADusedADexclusivelyADbyADadvancedADpracticeADpsychiatricADnursesA
DnorADisADitADrelevantADforADonlyADbehaviorADtherapiesADorADbrainADtraumaADsinceADdea
lingADwithADtheADresultsADofADnormalADandADabnormalADbrainADfunctionADisADaADrespon
sibilityADofADallADnursesADprovidingADallADtypesADofADcareADtoADtheADpsychiatricADpatien
t.
5. AADpatientADasksADtheADnurse,ADMyADwifeADhasADbreastADcancer.ADCouldADitADbe
ADcausedADbyADherADchronicADdepression? ADWhichADresponseADisADsupportedADby
ADresearchADdata?
a. TooADmuchADstressADhasADbeenADprovenADtoADcauseADallADkindsADofADcancer.
b. ThereADhaveADbeenADnoADresearchADstudiesADdoneADonADstressADandADdiseaseADyet.
c. StressADdoesADcauseADtheADreleaseADofADfactorsADthatADsuppressADtheADimmuneADsyst
em.
d. ThereADappearsADtoADbeADlittleADconnectionADbetweenADstressADandADdiseasesADofADt
heADbody
ANS:ADC
ResearchADindicatesADthatADstressADcausesADaADreleaseADofADcorticotropin-
releasingADfactorsADthatADsuppressADtheADimmuneADsystem.ADStudiesADindicateADthatADp
sychiatricADdisordersADsuchADasADmoodADdisordersADareADsometimesADassociatedADwithA
DdecreasedADfunctioningADofADtheADimmuneADsystem.ADResearchADdoesADnotADsupportAD
aADconnectionADbetweenADmanyADcancersADandADstress.ADThereADisADaADsignificantADa
, mountADofADresearchADaboutADstressADandADtheADbody.ADResearchADhasADshownADthatAD
thereADareADsomeADconnectionsADbetweenADstressADandADphysicalADdisease.
Stahl:ADStahl'sADEssentialADPsychopharmacology:ADNeuroscientificADBasisADandADPracticalADAp
plicationsAD5thADEdition
MULTIPLEADCHOICE
1. AADpatientADwithADdepressionADmentionsADtoADtheADnurse,ADMyADmotherADsaysADd
epressionADisADaADchemicalADdisorder.ADWhatADdoesADsheADmean?ADTheADnursesADres
ponseADisADbasedADonADtheADtheoryADthatADdepressionADprimarilyADinvolvesADwhichAD
ofADtheADfollowingADneurotransmitters?
a. CortisolADandADGABA
b. COMTADandADglutamate
c. MonamineADandADglycine
d. SerotoninADandADnorepinephrine
ANS:ADD
OneADpossibleADcauseADofADdepressionADisADthoughtADtoADinvolveADoneADorADmoreADneur
otransmitters.ADSerotoninADandADnorepinephrineADhaveADbeenADfoundADtoADbeADimport
antADinADtheADregulationADofADdepression.ADThereADisADnoADresearchADtoADsupportADthat
ADtheADotherADoptionsADplayADaADsignificantADroleADinADtheADdevelopmentADofADdepress
ion.
2. AADpatientADhasADexperiencedADaADstrokeAD(cerebralADvascularADaccident)ADthatADha
sADresultedADinADdamageADtoADtheADBrocaADarea.ADWhichADevaluationADdoesADtheADnur
seADconductADtoADreinforceADthisADdiagnosis?
a. ObservingADtheADpatientADpickADupADaADspoon
b. AskingADtheADpatientADtoADreciteADtheADalphabet
c. MonitoringADtheADpatientsADbloodADpressure
d. ComparingADtheADpatientsADgripADstrengthADinADbothADhands
ANS:ADB
AccidentsADorADstrokesADthatADdamageADBrocasADareaADmayADresultADinADtheADinabilityA
DtoADspeakAD(i.e.,ADmotorADaphasia).ADFineADmotorADskills,ADbloodADpressureADcontrol,A
DandADmuscleADstrengthADareADnotADcontrolledADbyADtheADBrocaADareaADofADtheADleftADf
rontalADlobe.
3. TheADpatientADdiagnosedADwithADschizophreniaADasksADwhyADpsychotropicADmedic
ationsADareADalwaysADprescribedADbyADtheADdoctor.ADTheADnursesADanswerADwillADbeADb
asedADonADinformationADthatADtheADtherapeuticADactionADofADpsychotropicADdrugsADisA
Dthe
a.ADresult
TheADADoftemporal
ADtheirADAD
effect ADon:
lobe;AD especiallyADWernickesADarea
b. DendritesADandADtheirADabilityADtoADtransmitADelectricalADimpulses
c. TheADregulationADofADneurotransmittersADespeciallyADdopamine
d. TheADperipheralADnervousADsystemADsensitivityADtoADtheADpsychotropicADmedication
s
,ANS:ADC
MedicationsADusedADtoADtreatADpsychiatricADdisordersADoperateADinADandADaroundADtheAD
synapticADcleftADandADhaveADactionADatADtheADneurotransmitterADlevel,ADespeciallyADinA
DtheADcaseADofADschizophrenia,ADonADdopamine.ADTheADWernickesADarea,ADdendriteADfu
nction,ADorADtheADsensitivityADofADtheADperipheralADnervousADsystemADareADnotADreleva
ntADtoADeitherADschizophreniaADorADpsychotropicADmedications.
4. AADstudentADnurseADmuttersADthatADitADseemsADentirelyADunnecessaryADtoADhaveADtoA
DstruggleADwithADunderstandingADtheADanatomyADandADphysiologyADofADtheADneurolo
gicADsystem.ADTheADmentorADwouldADbaseADaADresponseADonADtheADunderstandingADt
hatADitADis:
NecessaryADbutADgenerallyADforADpsychiatricADnursesADwhoADfocusADprimarilyAD
a. onADbehavioralADinterventions
AADcomplexADundertakingADthatADadvanceADpracticeADpsychiatricADnursesADfreq
b. uentlyADuseADinADtheirADpractice
ImportantADprimarilyADforADtheADnursingADassessmentADofADpatientsADwithADbrainADt
c. raumacausedADcognitiveADsymptoms
NecessaryADforADplanningADpsychiatricADcareADforADallADpatientsADespeciallyADthose
d. ADexperiencingADpsychiatricADdisorders
ANS:ADD
NursesADmustADunderstandADthatADmanyADsymptomsADofADpsychiatricADdisordersADhav
eADaADneurologicADbasis,ADalthoughADtheADsymptomsADareADmanifestedADbehaviorally.A
DThisADunderstandingADfacilitatesADeffectiveADcareADplanning.ADTheADfoundationADofADk
nowledgeADisADnotADusedADexclusivelyADbyADadvancedADpracticeADpsychiatricADnursesA
DnorADisADitADrelevantADforADonlyADbehaviorADtherapiesADorADbrainADtraumaADsinceADdea
lingADwithADtheADresultsADofADnormalADandADabnormalADbrainADfunctionADisADaADrespon
sibilityADofADallADnursesADprovidingADallADtypesADofADcareADtoADtheADpsychiatricADpatien
t.
5. AADpatientADasksADtheADnurse,ADMyADwifeADhasADbreastADcancer.ADCouldADitADbe
ADcausedADbyADherADchronicADdepression? ADWhichADresponseADisADsupportedADby
ADresearchADdata?
a. TooADmuchADstressADhasADbeenADprovenADtoADcauseADallADkindsADofADcancer.
b. ThereADhaveADbeenADnoADresearchADstudiesADdoneADonADstressADandADdiseaseADyet.
c. StressADdoesADcauseADtheADreleaseADofADfactorsADthatADsuppressADtheADimmuneADsyst
em.
d. ThereADappearsADtoADbeADlittleADconnectionADbetweenADstressADandADdiseasesADofADt
heADbody
ANS:ADC
ResearchADindicatesADthatADstressADcausesADaADreleaseADofADcorticotropin-
releasingADfactorsADthatADsuppressADtheADimmuneADsystem.ADStudiesADindicateADthatADp
sychiatricADdisordersADsuchADasADmoodADdisordersADareADsometimesADassociatedADwithA
DdecreasedADfunctioningADofADtheADimmuneADsystem.ADResearchADdoesADnotADsupportAD
aADconnectionADbetweenADmanyADcancersADandADstress.ADThereADisADaADsignificantADa
, mountADofADresearchADaboutADstressADandADtheADbody.ADResearchADhasADshownADthatAD
thereADareADsomeADconnectionsADbetweenADstressADandADphysicalADdisease.