Karch's Focus on Pharmacology 8th
Ed. | Chapter 16 Final Exam Questions
and Actual Answers.
While providing client teaching relative to inflammatory disorders, the nurse would explain the
presence of inflammation as: - Answer an attempt by the body to remove the damaging agent
and repair the damaged tissue.
Rheumatoid factor (RF) interacts with circulating IgG to form immune complexes that deposit in
the joints precipitating an inflammatory reaction. - Answer TRUE
The nurse is discussing ethnic differences in response to medication with nursing students.
What group of people would the nurse tell the students have a decreased sensitivity to pain-
relieving effects of anti-inflammatory drugs and should be educated concerning signs and
symptoms of gastrointestinal bleeding from use of these drugs? - Answer Black Americans
A 65-year-old man who just had a heart attack is placed on aspirin, 81 mg daily. The nurse is
explaining the purpose of this medication to the client and his wife. What would be the nurses
best explanation? - Answer The aspirin is being prescribed because it reduces your risk of a
second heart attack.
A client with acute joint inflammation tells the nurse , "I've been taking acetaminophen as it's
ordered on the bottle, but my swelling and inflammation doesn't seem to be getting better."
What should the nurse teach the client? - Answer Acetaminophen has no effect on
inflammation."
A 7-year-old child with juvenile arthritis has been prescribed auranofin 0.125 mg/kg/day PO.
The client weighs 88 lbs. How many mg of auranofin should the nurse administer each day? -
Answer 88/2.2 = 40
40 x 0.125 = 5
When assessing a client who is to receive celecoxib, a history of which disease process or
condition would be most important to assess? - Answer cardiac disease
A COX-1 inhibitor has known protective effects on what organ? Select all that apply. - Answer
Stomach
, A nurse is reviewing a journal article about a nonsteroidal anti-inflammatory drug (NSAID) that
is associated with an increased risk of cardiovascular thrombosis, myocardial infarction, and
stroke. The nurse is most likely reading about which drug? - Answer celecoxib
What drugs used to treat rheumatoid arthritis are contraindicated in a client who has a history
of toxic levels of heavy metals? - Answer gold salts
A clinic nurse is caring for a patient who is taking a COX-2 inhibitor. The nurse knows that this
patient needs to be evaluated for what conditions? (Select all that apply.) - Answer Bleeding
time
GI effects
Water retention
What should a nurse recognize as a property of ibuprofen/Motrin? (Select all that apply.) -
Answer Analgesic
Anti-inflammatory
Antipyretic
A nurse is assigned to care for a patient with arthritis in a health care facility. The patient has
been prescribed celecoxib. Celecoxib is contraindicated in clients with: - Answer allergy to
sulfonamides.
A client is prescribed ibuprofen for knee pain. When the client is admitted to the hospital with
abdominal pain, which assessment should the nurse prioritize? - Answer assessment for
hematemesis
The client has been prescribed one aspirin a day. The nurse understands that is prescribed for
which of the following? - Answer To inhibit platelet aggregation
A client is receiving anakinra as treatment for arthritis. The nurse understands that this drug
acts in which manner? - Answer Blocks interleukin-1
When acetylsalicylic acid is administered in low doses, it blocks the synthesis of thromboxane
A2. What physiologic effect results from this action? - Answer Platelet aggregation is inhibited.
Ed. | Chapter 16 Final Exam Questions
and Actual Answers.
While providing client teaching relative to inflammatory disorders, the nurse would explain the
presence of inflammation as: - Answer an attempt by the body to remove the damaging agent
and repair the damaged tissue.
Rheumatoid factor (RF) interacts with circulating IgG to form immune complexes that deposit in
the joints precipitating an inflammatory reaction. - Answer TRUE
The nurse is discussing ethnic differences in response to medication with nursing students.
What group of people would the nurse tell the students have a decreased sensitivity to pain-
relieving effects of anti-inflammatory drugs and should be educated concerning signs and
symptoms of gastrointestinal bleeding from use of these drugs? - Answer Black Americans
A 65-year-old man who just had a heart attack is placed on aspirin, 81 mg daily. The nurse is
explaining the purpose of this medication to the client and his wife. What would be the nurses
best explanation? - Answer The aspirin is being prescribed because it reduces your risk of a
second heart attack.
A client with acute joint inflammation tells the nurse , "I've been taking acetaminophen as it's
ordered on the bottle, but my swelling and inflammation doesn't seem to be getting better."
What should the nurse teach the client? - Answer Acetaminophen has no effect on
inflammation."
A 7-year-old child with juvenile arthritis has been prescribed auranofin 0.125 mg/kg/day PO.
The client weighs 88 lbs. How many mg of auranofin should the nurse administer each day? -
Answer 88/2.2 = 40
40 x 0.125 = 5
When assessing a client who is to receive celecoxib, a history of which disease process or
condition would be most important to assess? - Answer cardiac disease
A COX-1 inhibitor has known protective effects on what organ? Select all that apply. - Answer
Stomach
, A nurse is reviewing a journal article about a nonsteroidal anti-inflammatory drug (NSAID) that
is associated with an increased risk of cardiovascular thrombosis, myocardial infarction, and
stroke. The nurse is most likely reading about which drug? - Answer celecoxib
What drugs used to treat rheumatoid arthritis are contraindicated in a client who has a history
of toxic levels of heavy metals? - Answer gold salts
A clinic nurse is caring for a patient who is taking a COX-2 inhibitor. The nurse knows that this
patient needs to be evaluated for what conditions? (Select all that apply.) - Answer Bleeding
time
GI effects
Water retention
What should a nurse recognize as a property of ibuprofen/Motrin? (Select all that apply.) -
Answer Analgesic
Anti-inflammatory
Antipyretic
A nurse is assigned to care for a patient with arthritis in a health care facility. The patient has
been prescribed celecoxib. Celecoxib is contraindicated in clients with: - Answer allergy to
sulfonamides.
A client is prescribed ibuprofen for knee pain. When the client is admitted to the hospital with
abdominal pain, which assessment should the nurse prioritize? - Answer assessment for
hematemesis
The client has been prescribed one aspirin a day. The nurse understands that is prescribed for
which of the following? - Answer To inhibit platelet aggregation
A client is receiving anakinra as treatment for arthritis. The nurse understands that this drug
acts in which manner? - Answer Blocks interleukin-1
When acetylsalicylic acid is administered in low doses, it blocks the synthesis of thromboxane
A2. What physiologic effect results from this action? - Answer Platelet aggregation is inhibited.
