Final MN 650 Specialized
Pharmacology for the AGACNP
Exam 2025 Questions and Answers
Common infections in the Geriatrics - ANSWER✔✔-MRSA- (uncommon from animals)
Assess body systems function level prior to prescribing ABX therapy - ANSWER✔✔-
(i.e. renal function).
Antifungals metabolize through the - ANSWER✔✔-Liver
▪An antibiogram is: - ANSWER✔✔-overall profile of antimicrobial susceptibility testing
results of a specific microorganism to a battery of antimicrobial drugs
Cultures and sensitivity tell you - ANSWER✔✔-Tells you:
-Identifies bacteria/fungus present
-Sensitivity results based on data
Cultures and sensitivity DONT tell you: - ANSWER✔✔--Infection vs. colonization vs.
contamination
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,-You would not treat colonization or contamination
-Which ABX to use.
MIC (Minimum inhibitory concentration) - ANSWER✔✔-min. concentration of an ABX
needed to inhibit proliferation & is important for definitive TX.
Cultures and sensitivity reports start with: - ANSWER✔✔-Start w/ beta-lactam if
possible, especially in severe infections (best data supporting their use)
-Exception: atypical infections
▪You are reviewing a report on a urine culture of a 55 year old female with
pyelonephritis. A culture was done which has revealed growth of Ecoli Susceptibility
testing show minimum inhibitory concentration (MIC) score of 1 for Ciprofloxacin 2 for
Levafloxacin 4 for Ceftriaxone and 16 for Nitrofurantoin. Considering the MIC score the
most appropriate antibiotic to prescribe would be ciprofloxacin. - ANSWER✔✔-Chose
lower MIC score
Fluroquinolones (ex: ciprofloxacin) are most associated with causing: - ANSWER✔✔-
pseudomembranous colitis.
S/S of pseudomembranous colitis - ANSWER✔✔-recent ABX use followed by diarrhea
with possible blood
To prevent further development of ABX resistance, it is recommended that
fluoroquinolones be reserved for treatment of: - ANSWER✔✔-CAP with comorbidities.
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,If your patient is allergic to sulfonamides, they most likely will have a cross-sensitivity
to: - ANSWER✔✔-loop diuretics, sulfonylureas, & thiazide diuretics.
If you patient cannot reliably take PO ABX, ___ or ___ would be an appropriate
treatment option. - ANSWER✔✔-IM or IV
Prebiotics are recommended to be co-administered with: - ANSWER✔✔-ABX
Rx half-life is longer in: - ANSWER✔✔-older adults (watch for atypical reactions)
Monitor liver enzymes when on __ tx. - ANSWER✔✔-long term antifungal tx
Patients taking isoniazid for TB may experience peripheral neuropathy. To prevent,
prescribe: - ANSWER✔✔-pyridoxine (vit B6).
Because microbiological results do not become available for 24 to 72 hours, initial
therapy for infection is often _____ and guided by the clinical presentation. -
ANSWER✔✔-empiric
empiric is broad-spectrum & treats: ____
Once C&S is received, a more narrowed focused ABX can be prescribed. -
ANSWER✔✔-gram-positive and gram-negative, diverse fungi, or parasites
How soon should newly diagnosed HIV patients should start antiviral treatment? -
ANSWER✔✔-as soon as the positive diagnosis is given
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, Initiation of ARV can prevent complications of AIDS-related diseases, such as: -
ANSWER✔✔-PCP pneumonia. (pneumocystis jiroveci pneumonia)
When a Herpes Simplex 2 Dx is suspected ___ is the Rx of choice. - ANSWER✔✔-
Acyclovir
You are evaluating a patient in the ER who is complaining of pain to his right leg that
developed yesterday. The pain has become increasingly worse in the last few hours to
the point that the patient's wife called EMS to the house to transport him to your ER.
His wife tells you he has not been acting right over the last few hours and seems "out of
it.". You, the AGACNP suspect an infection and order labs/cx/start abx. While
initiating therapy the patient becomes hypotensive and is given a fluid bolus. You
preform an in-depth exam on this patient and notice crepitus on the patient's right
thigh. You admitted him to your ICU and write orders to initiate broad spectrum
antibiotics for this patient. The best antimicrobial combination to begin on this patient is
_______ - ANSWER✔✔-Doribax (for nec fasc)
Twenty-year-old Annie comes to the clinic complaining of copious yellow-green eye
discharge. Gram stain indicates she most likely has gonococcal conjunctivitis. While
awaiting the culture results, the plan of care should be: - ANSWER✔✔-IM ceftriaxone
Although MRSA is uncommon in animal bites, ABX Tx is needing in cat bites due to
their oral flora. Initial cat bite treatment would be: - ANSWER✔✔-A thorough cleansing
and debridement, Xray, and amoxicillin-clavulanic acid/7-day regimine.
COPYRIGHT © 2025 ALL RIGHTS RESERVED
Pharmacology for the AGACNP
Exam 2025 Questions and Answers
Common infections in the Geriatrics - ANSWER✔✔-MRSA- (uncommon from animals)
Assess body systems function level prior to prescribing ABX therapy - ANSWER✔✔-
(i.e. renal function).
Antifungals metabolize through the - ANSWER✔✔-Liver
▪An antibiogram is: - ANSWER✔✔-overall profile of antimicrobial susceptibility testing
results of a specific microorganism to a battery of antimicrobial drugs
Cultures and sensitivity tell you - ANSWER✔✔-Tells you:
-Identifies bacteria/fungus present
-Sensitivity results based on data
Cultures and sensitivity DONT tell you: - ANSWER✔✔--Infection vs. colonization vs.
contamination
COPYRIGHT © 2025 ALL RIGHTS RESERVED
,-You would not treat colonization or contamination
-Which ABX to use.
MIC (Minimum inhibitory concentration) - ANSWER✔✔-min. concentration of an ABX
needed to inhibit proliferation & is important for definitive TX.
Cultures and sensitivity reports start with: - ANSWER✔✔-Start w/ beta-lactam if
possible, especially in severe infections (best data supporting their use)
-Exception: atypical infections
▪You are reviewing a report on a urine culture of a 55 year old female with
pyelonephritis. A culture was done which has revealed growth of Ecoli Susceptibility
testing show minimum inhibitory concentration (MIC) score of 1 for Ciprofloxacin 2 for
Levafloxacin 4 for Ceftriaxone and 16 for Nitrofurantoin. Considering the MIC score the
most appropriate antibiotic to prescribe would be ciprofloxacin. - ANSWER✔✔-Chose
lower MIC score
Fluroquinolones (ex: ciprofloxacin) are most associated with causing: - ANSWER✔✔-
pseudomembranous colitis.
S/S of pseudomembranous colitis - ANSWER✔✔-recent ABX use followed by diarrhea
with possible blood
To prevent further development of ABX resistance, it is recommended that
fluoroquinolones be reserved for treatment of: - ANSWER✔✔-CAP with comorbidities.
COPYRIGHT © 2025 ALL RIGHTS RESERVED
,If your patient is allergic to sulfonamides, they most likely will have a cross-sensitivity
to: - ANSWER✔✔-loop diuretics, sulfonylureas, & thiazide diuretics.
If you patient cannot reliably take PO ABX, ___ or ___ would be an appropriate
treatment option. - ANSWER✔✔-IM or IV
Prebiotics are recommended to be co-administered with: - ANSWER✔✔-ABX
Rx half-life is longer in: - ANSWER✔✔-older adults (watch for atypical reactions)
Monitor liver enzymes when on __ tx. - ANSWER✔✔-long term antifungal tx
Patients taking isoniazid for TB may experience peripheral neuropathy. To prevent,
prescribe: - ANSWER✔✔-pyridoxine (vit B6).
Because microbiological results do not become available for 24 to 72 hours, initial
therapy for infection is often _____ and guided by the clinical presentation. -
ANSWER✔✔-empiric
empiric is broad-spectrum & treats: ____
Once C&S is received, a more narrowed focused ABX can be prescribed. -
ANSWER✔✔-gram-positive and gram-negative, diverse fungi, or parasites
How soon should newly diagnosed HIV patients should start antiviral treatment? -
ANSWER✔✔-as soon as the positive diagnosis is given
COPYRIGHT © 2025 ALL RIGHTS RESERVED
, Initiation of ARV can prevent complications of AIDS-related diseases, such as: -
ANSWER✔✔-PCP pneumonia. (pneumocystis jiroveci pneumonia)
When a Herpes Simplex 2 Dx is suspected ___ is the Rx of choice. - ANSWER✔✔-
Acyclovir
You are evaluating a patient in the ER who is complaining of pain to his right leg that
developed yesterday. The pain has become increasingly worse in the last few hours to
the point that the patient's wife called EMS to the house to transport him to your ER.
His wife tells you he has not been acting right over the last few hours and seems "out of
it.". You, the AGACNP suspect an infection and order labs/cx/start abx. While
initiating therapy the patient becomes hypotensive and is given a fluid bolus. You
preform an in-depth exam on this patient and notice crepitus on the patient's right
thigh. You admitted him to your ICU and write orders to initiate broad spectrum
antibiotics for this patient. The best antimicrobial combination to begin on this patient is
_______ - ANSWER✔✔-Doribax (for nec fasc)
Twenty-year-old Annie comes to the clinic complaining of copious yellow-green eye
discharge. Gram stain indicates she most likely has gonococcal conjunctivitis. While
awaiting the culture results, the plan of care should be: - ANSWER✔✔-IM ceftriaxone
Although MRSA is uncommon in animal bites, ABX Tx is needing in cat bites due to
their oral flora. Initial cat bite treatment would be: - ANSWER✔✔-A thorough cleansing
and debridement, Xray, and amoxicillin-clavulanic acid/7-day regimine.
COPYRIGHT © 2025 ALL RIGHTS RESERVED
