TREATMENT OF LYMPHOMA'S||COMPLETE
SOLUTION RATED A+|| 2025!!
1. How is lymphoma treated Potential treatment options include
? — Chemotherapy
— Radiation therapy
— Immune therapies (ex. monoclonal antibodies)
— Stem cell transplant
— Combinations of the above
— Observation
2. How do we decide.. what Depends on many key factors
to use? When to treat? for — Subtype of lymphoma —Is it curable?
lymphoma —If not, are there symptoms to be treated?
— Stage of disease
— Patient wishes
3. Give examples of Acronyms used for chemotherapy regimens:
the Main Chemotherapy ABVD, CHOP-R, CVP-R
treatment drugs for lym-
- Taken orally or by injection
phoma
- Used individually or in combination
- Typically given in multiple "cycles"
4. The target of radiation radiation --> localized to radiation field
therapy is , while chemotherapy --> systemic
chemotherapy is ?
5. What is an example of an - Monoclonal antibodies such as RlTUXIMAB
immune therapy for lym- are treatments that manipulate the immune system to fight cancer
phoma?
6. What is the target of the - Rituximab targets CD20 antigen on surface of B-cell lymphoma cells
monoclonal antibody Rit- .
uximab? - Monoclonal Antibodies Proteins designed to recognize and attack
specific molecules on surface of cells .
, TREATMENT OF LYMPHOMA'S||COMPLETE
SOLUTION RATED A+|| 2025!!
7. What is a likely diagnosis Suspect a diagnosis of lymphoma, refer to a surgeon for excisional
for these symtpoms: biopsy of cervical lymph node (FNAB suflcient).
28 year old man, presents
Pathology shows Classical Hodgkin lymphoma, nodular sclerosing
with "lump" in the left
subtype.
neck
Dry cough, pressure-type
chest pain.
Physical exam: several en-
larged lymph
nodes, 'rubbery' consis-
tency
— left anterior cervical (3
x 3 cm)
— left supraclavicular ( 2
X 1 cm)
Chest x-ray: large medi-
astinal mass
8. What should you look for HISTORY
in the history (if lym- — History of the lymph node — when it first appeared, rapidity of
phoma is suspected? growth, any pain
— B-symptoms (weight loss, fever, night sweats)
— Pruritus, lymph node pain with alcohol
— HIV risk factors (autoimmune problems?)
— Shortness of breath, abdominal pain, superior vena cava obstruc-
tion, etc. -- > clues as to where the lymph node is
9. What should you look for PHYSICAL EXAM
in the physical exam (if — Full lymph node exam.
lymphoma is suspected? Describe: number, size, location (contiguous or not?) consistency (rub-
bery vs firm), mobility, tender/non-tender.
SOLUTION RATED A+|| 2025!!
1. How is lymphoma treated Potential treatment options include
? — Chemotherapy
— Radiation therapy
— Immune therapies (ex. monoclonal antibodies)
— Stem cell transplant
— Combinations of the above
— Observation
2. How do we decide.. what Depends on many key factors
to use? When to treat? for — Subtype of lymphoma —Is it curable?
lymphoma —If not, are there symptoms to be treated?
— Stage of disease
— Patient wishes
3. Give examples of Acronyms used for chemotherapy regimens:
the Main Chemotherapy ABVD, CHOP-R, CVP-R
treatment drugs for lym-
- Taken orally or by injection
phoma
- Used individually or in combination
- Typically given in multiple "cycles"
4. The target of radiation radiation --> localized to radiation field
therapy is , while chemotherapy --> systemic
chemotherapy is ?
5. What is an example of an - Monoclonal antibodies such as RlTUXIMAB
immune therapy for lym- are treatments that manipulate the immune system to fight cancer
phoma?
6. What is the target of the - Rituximab targets CD20 antigen on surface of B-cell lymphoma cells
monoclonal antibody Rit- .
uximab? - Monoclonal Antibodies Proteins designed to recognize and attack
specific molecules on surface of cells .
, TREATMENT OF LYMPHOMA'S||COMPLETE
SOLUTION RATED A+|| 2025!!
7. What is a likely diagnosis Suspect a diagnosis of lymphoma, refer to a surgeon for excisional
for these symtpoms: biopsy of cervical lymph node (FNAB suflcient).
28 year old man, presents
Pathology shows Classical Hodgkin lymphoma, nodular sclerosing
with "lump" in the left
subtype.
neck
Dry cough, pressure-type
chest pain.
Physical exam: several en-
larged lymph
nodes, 'rubbery' consis-
tency
— left anterior cervical (3
x 3 cm)
— left supraclavicular ( 2
X 1 cm)
Chest x-ray: large medi-
astinal mass
8. What should you look for HISTORY
in the history (if lym- — History of the lymph node — when it first appeared, rapidity of
phoma is suspected? growth, any pain
— B-symptoms (weight loss, fever, night sweats)
— Pruritus, lymph node pain with alcohol
— HIV risk factors (autoimmune problems?)
— Shortness of breath, abdominal pain, superior vena cava obstruc-
tion, etc. -- > clues as to where the lymph node is
9. What should you look for PHYSICAL EXAM
in the physical exam (if — Full lymph node exam.
lymphoma is suspected? Describe: number, size, location (contiguous or not?) consistency (rub-
bery vs firm), mobility, tender/non-tender.
