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Array CGH Exam Review Questions And Answers 2025 A+ Structural variant - ANS-a genomic alteration that involves segments(s) of DNA, microscopic or submicroscopic Structural abnormality - ANS-a structural variant that is disease causing or discovered as part of a disease study CGH - ANS-a tool designed to identify copy number changes. Low resolution (5-10 Mb for insertions). 2 Mb for deletions Array CGH - ANS-(matrix CGH), Large insert clones spanning 13q14. High resolution (75-130 kb) Specific genomic "hotspot" arrays or disease specific arrays - ANS-Target clones span a region frequently associated with copy number changes in a neoplasm or a region harboring a known gene involved in a disease. Prior knowledge of regions of interest known. Chromosome specific arrays - ANS-
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