NURS646 Midterm Exam With
Complete Solution
True or False: protein bound drugs are likely to be more bioavailable in infants - Answer
true
In the neonate, the proportion of body weight varies from adults in which of the following
ways?
1.
The proportion of intracellular fluid increases as the infant matures.
2.
The neonate exchanges extracellular fluid more rapidly than an adult.
3.
A larger milligram per kilogram of water soluble drug is needed.
4.
A smaller milligram per kilogram of water soluble drug is needed. - Answer 3. A larger
milligram per kilogram of water soluble drug is needed.
Some therapeutic medications dissolve very easily in fat and there fore can stay in the
body for long periods of time. In order to eliminate these drugs in the urine they have to
be converted to a ________ form.
1.
hydrophilic
2.
lipophobic
3.
inactive
4.
neutralized - Answer 1. hydrophilic
During the first month of life, infants have relative achlorhydria which will impact
absorption of medications. What is achlorhydria?
, 1.
Decreased gastric acid
2.
Decreased bile salt
3.
Elevated bilirubin
4.
Increased motility - Answer 1. Decreased gastric acid
Which of the following factors increases GI absorption in the infant?
1.
A proportionally greater surface area in the small intestine
2.
Increased peristaltic activity
3.
Elevated pancreatic enzymes
4.
High concentration of bile salts - Answer 1. A proportionally greater surface area in the
small intestine
A child is preparing to enter kindergarten in the fall, and has not received vaccinations
since the age of 6 months. The APN should first:
1.
Check the Center for Disease Control and Prevention (CDC) website for information
2.
Refer the child and parents to social worker
3.
Consult the inserts of the various vaccinations to determine best schedule
4.
Contact the local pharmacist for advice - Answer 1. Check the Center for Disease
Complete Solution
True or False: protein bound drugs are likely to be more bioavailable in infants - Answer
true
In the neonate, the proportion of body weight varies from adults in which of the following
ways?
1.
The proportion of intracellular fluid increases as the infant matures.
2.
The neonate exchanges extracellular fluid more rapidly than an adult.
3.
A larger milligram per kilogram of water soluble drug is needed.
4.
A smaller milligram per kilogram of water soluble drug is needed. - Answer 3. A larger
milligram per kilogram of water soluble drug is needed.
Some therapeutic medications dissolve very easily in fat and there fore can stay in the
body for long periods of time. In order to eliminate these drugs in the urine they have to
be converted to a ________ form.
1.
hydrophilic
2.
lipophobic
3.
inactive
4.
neutralized - Answer 1. hydrophilic
During the first month of life, infants have relative achlorhydria which will impact
absorption of medications. What is achlorhydria?
, 1.
Decreased gastric acid
2.
Decreased bile salt
3.
Elevated bilirubin
4.
Increased motility - Answer 1. Decreased gastric acid
Which of the following factors increases GI absorption in the infant?
1.
A proportionally greater surface area in the small intestine
2.
Increased peristaltic activity
3.
Elevated pancreatic enzymes
4.
High concentration of bile salts - Answer 1. A proportionally greater surface area in the
small intestine
A child is preparing to enter kindergarten in the fall, and has not received vaccinations
since the age of 6 months. The APN should first:
1.
Check the Center for Disease Control and Prevention (CDC) website for information
2.
Refer the child and parents to social worker
3.
Consult the inserts of the various vaccinations to determine best schedule
4.
Contact the local pharmacist for advice - Answer 1. Check the Center for Disease
