Krok 1 - Biochemistry exam

Depressions and emotional insanities result from the deficit of noradrenalin, serotonin and other biogenic amines in the brain. Their concentration in the synapses can be increased by means of the antidepressants that inhibit the following enzyme: - ansmonoamine oxidase A patient with high rate of obesity was advised to use carnitine as a food additive in order to enhance "fat burning". What is the role of carnitine in the process of fat oxidation? - ansTransport of FFA (free fatty acids) from cytosol to the mitochondria A 9-month-old infant is fed with artificial formulas with unbalanced vitamin $B_6$ concentration. The infant presents with pellagral dermatitis, convulsions, anaemia. Convulsion development might be caused by the disturbed formation of: - ansGABA Patients who suffer from severe diabetes and don't receive insulin have metabolic acidosis. This is caused by increased concentration of the following metabolites - ansketone bodies It was found out that some compounds, for instance fungi toxins and some antibiotics can inhibit activity of RNA-polymerase. What process will be disturbed in a cell in case of inhibition of this enzyme? - anstranscription In case of enterobiasis acrihine - the structural analogue of vitamin $B_2$ - is administered. The synthesis disorder of which enzymes does this medicine cause in microorganisms? - ansFAD-dependent dehydrogenases