triacylglycerides' catabolism
In theLiver ... Glycolysis/Guconeogenesis
+
WADt NADH + H
ADP
①
When insulin (fasting) -H Ar Not
&
Ot
-
Lo POz2- -
2 0
-OH
↳
TRIUSE
PHOJPHATE
O
-I
N- ~
GLYCEROL OPOg2
Y
Ho
10 GLYCEROL
epinen a se
Ol I
-
I SOMELASE
-
L-Glycerol
hume ywuyon
KINASE
, inside 3-phosphate
PHOSPHATE
Dihydroxy acetone - pozz-
DEHYOROGE-
000000000 Elycerol phosphale
Adeny
NASE
O
lath nan
nana Gycealdehyde
wurvvuv Cyclase vorvv
↑
perfect eq (constant 1)
VVV desirise 3-phosphale
=
not =>
00000000
.
000000000
outside
.
P m
000
G-protein
&
7TM
-X-subunit 3Ht O
S Il
activates Acyc COA O
-1
7 transmem- SYNTHETASE Il
Amo HS-COA <-
-
↑ -CA
(cyclic +
brunf
ATP CAMP o- X -
*
receptor activates
- fally acy 1 R COA
& Y CoA
-
↑ lipaces
+
Alp
Ampto Acyl
5H20 O
p
·-
KINASE (acrivation PyROPHOSPHATASE
&
Diacy Iglycerol 8 Acyl Carminine
IA
A Pi -
Carnitine
phosphoriylates degradated now
>
T
I
ACYCTRANSFERASE
i Transco
gets CARNITININE -
to avoid
TRIALY LEYCEROL due
LIPASE
TRIACYCGUCEROL 2
backword rxn no nu
LIPASE
wurru
⑦O
- Triacylglyceo t pefe CARNIRNE
000000
did
↑ ↑ - ana
T
Acultransferase
mi a Carnihn
-- 1 carniline
E
S ↑
S
owcayon Insulin
4
:
Cot COA
Acyl I
O
CoA Ex) Palmitale (16C)
R
=x) g-
AyCoenase FADH2
CA
B-OXIDATION PATWAY (Mitochundial
- ,
trans-82 -
Enoy/CoA
H+ + NADH Was
Enolot
"
The-CoA Y1scon
&
,
O
O
R Il Con
-1 s t Il con -
CIs oxidation
Hz lot CoA
Acyl CoA
B-Ketothiolase L-3-hydroxy acyl L-3-Hydroxyacy1
Acetyl CoA
1-2 Cabons) 3-Ketoacyl COA dehydrogenase !
(Ex)2c)
(EX) 14C)
,
In theLiver ... Glycolysis/Guconeogenesis
+
WADt NADH + H
ADP
①
When insulin (fasting) -H Ar Not
&
Ot
-
Lo POz2- -
2 0
-OH
↳
TRIUSE
PHOJPHATE
O
-I
N- ~
GLYCEROL OPOg2
Y
Ho
10 GLYCEROL
epinen a se
Ol I
-
I SOMELASE
-
L-Glycerol
hume ywuyon
KINASE
, inside 3-phosphate
PHOSPHATE
Dihydroxy acetone - pozz-
DEHYOROGE-
000000000 Elycerol phosphale
Adeny
NASE
O
lath nan
nana Gycealdehyde
wurvvuv Cyclase vorvv
↑
perfect eq (constant 1)
VVV desirise 3-phosphale
=
not =>
00000000
.
000000000
outside
.
P m
000
G-protein
&
7TM
-X-subunit 3Ht O
S Il
activates Acyc COA O
-1
7 transmem- SYNTHETASE Il
Amo HS-COA <-
-
↑ -CA
(cyclic +
brunf
ATP CAMP o- X -
*
receptor activates
- fally acy 1 R COA
& Y CoA
-
↑ lipaces
+
Alp
Ampto Acyl
5H20 O
p
·-
KINASE (acrivation PyROPHOSPHATASE
&
Diacy Iglycerol 8 Acyl Carminine
IA
A Pi -
Carnitine
phosphoriylates degradated now
>
T
I
ACYCTRANSFERASE
i Transco
gets CARNITININE -
to avoid
TRIALY LEYCEROL due
LIPASE
TRIACYCGUCEROL 2
backword rxn no nu
LIPASE
wurru
⑦O
- Triacylglyceo t pefe CARNIRNE
000000
did
↑ ↑ - ana
T
Acultransferase
mi a Carnihn
-- 1 carniline
E
S ↑
S
owcayon Insulin
4
:
Cot COA
Acyl I
O
CoA Ex) Palmitale (16C)
R
=x) g-
AyCoenase FADH2
CA
B-OXIDATION PATWAY (Mitochundial
- ,
trans-82 -
Enoy/CoA
H+ + NADH Was
Enolot
"
The-CoA Y1scon
&
,
O
O
R Il Con
-1 s t Il con -
CIs oxidation
Hz lot CoA
Acyl CoA
B-Ketothiolase L-3-hydroxy acyl L-3-Hydroxyacy1
Acetyl CoA
1-2 Cabons) 3-Ketoacyl COA dehydrogenase !
(Ex)2c)
(EX) 14C)
,
