Biomedical Engineering Exam 2 questions with solutions

affinitycorrect answer: measure of how tightly a ligand binds to its receptor low K_D, high K_A, means high affinity equilibrium dialysiscorrect answer: - receptors in a semipermeable bad - bag placed in ligand solution - allowed to reach equilibrium agonistscorrect answer: enhance binding and signaling (antidepressant, opioids) antagonistscorrect answer: inhibit binding and signaling: tamoxifen (estrogen blocker/inhibitor) over-expression of _________ inhibits tumor suppressor proteinscorrect answer: oncoproteins oncoproteincorrect answer: a protein encoded by an oncogene that can cause a cell to turn into a tumor cell 4 types of signalingcorrect answer: cell-cell autocrine paracrine endocrine cell-cell signalingcorrect answer: - direct junction between cells - cardiac cells - respond very quick autocrine signalingcorrect answer: - signaling on itself - T-cell (immune response) paracrine signal