NCLEX Pharmacology: REVIEW-
Hematological Medications- Test
Questions and Answers Graded A+
2026 Update.
A home care nurse is visiting a client who was discharged to home with a prescription for
continued administration of enoxaparin (Lovenox) subcutaneously. What is the nurse's priority
assessment for this client?
1. Constipation
2. Fear of needles
3. Nausea or vomiting
4. Bleeding gums or bruising - Answer 4. Bleeding gums or bruising
Enoxaparin is an anticoagulant. An adverse effect of anticoagulant therapy is bleeding.
Accordingly, the nurse questions the client about signs and symptoms that could indicate
bleeding, such as bleeding gums, bruising, hematuria, or dark tarry stools.
The nurse is assigned to care for a client who was just admitted to the hospital for the
treatment of iron overload. The nurse anticipates that the health care provider will prescribe
which medication to treat the iron overload?
1. Granisetron
2. Ketoconazole
3. Deferoxamine
4. Terbinafine (Lamisil) - Answer 3. Deferoxamine
Deferoxamine is a medication used to treat iron overload. Granisetron is an antiemetic.
Ketoconazole and terbinafine are antifungal medications.
Epoetin alfa (Epogen, Procrit) has been prescribed for a client with chronic kidney disease who
is being cared for by a nursing student. The nursing instructor determines that the student
understands the procedure for administering the medication when the student states that
which route of administration is acceptable?
1. Oral
2. Z-track
3. Intramuscular
,4. Subcutaneous - Answer 4. Subcutaneous
Epoetin alfa is administered parenterally by the intravenous or subcutaneous route. It cannot be
given orally because it is a glycoprotein and would be degraded in the gastrointestinal tract.
Enoxaparin sodium (Lovenox) is prescribed for a client after hip replacement surgery. What
should the nurse prepare to have available in the event that an overdose of the medication
occurs?
1. Adrenalin
2. Vitamin K
3. Epinephrine
4. Protamine sulfate - Answer 4. Protamine sulfate
Enoxaparin sodium is an anticoagulant. Accidental overdose of this medication may lead to
bleeding complications. The antidote is protamine sulfate. Adrenalin is a trademarked
preparation of epinephrine, which normally is used to treat hypersensitivity reactions or acute
bronchial asthma attacks and bronchospasms. Vitamin K is the antidote for warfarin sodium
(Coumadin).
A client with a subarachnoid hemorrhage needs to have surgery delayed until a stable clinical
condition is achieved. The nurse prepares to administer which medication as prescribed to
prevent clot breakdown and dissolution?
1. Alteplase (Activase)
2. Warfarin (Coumadin)
3. Heparin sodium (Heparin)
4. Aminocaproic acid (Amicar) - Answer 4. Aminocaproic acid (Amicar)
Aminocaproic acid (Amicar) is an antifibrinolytic agent that prevents clot breakdown or
dissolution. It is commonly prescribed after subarachnoid hemorrhage if surgery is delayed or
contraindicated, to prevent further hemorrhage. Alteplase is a fibrinolytic that actively breaks
down clots. Warfarin and heparin sodium are anticoagulants that interfere with propagation or
growth of a clot.
A client is taking ticlopidine hydrochloride (Ticlid). The nurse should tell the client to avoid
which substance while taking this medication?
1. Vitamin C
, 2. Vitamin D
3. Acetaminophen (Tylenol)
4. Acetylsalicylic acid (aspirin) - Answer 4. Acetylsalicylic acid (aspirin)
Ticlopidine hydrochloride is a platelet aggregation inhibitor. It is used to decrease the risk of
thrombotic stroke in clients with precursor symptoms. Because it is an antiplatelet agent, other
medications that precipitate or aggravate bleeding should be avoided during its use. Therefore,
aspirin or any aspirin-containing product should be avoided. The substances in options 1, 2, and
3 are safe to consume.
A client is admitted to the hospital emergency department with an acute anterior wall
myocardial infarction. The nurse discusses streptokinase (Streptase) therapy with the client and
spouse. The spouse is concerned about the dangers of this treatment. Which statement by the
nurse is appropriate?
1. "There is no reason to worry. We use this medication all the time."
2. "I'm certain you made the correct decision to use this medication."
3. "You have concerns about whether this treatment is the best option."
4. "Your loved one is very ill. The health care provider has made the best decision for you." -
Answer 3. "You have concerns about whether this treatment is the best option."
Paraphrasing is restating the client's or family members' own words. This allows the client and
family members to express their concerns and talk through the decisions that have been made.
Option 1 is offering false reassurance. In option 2, the nurse is expressing approval, which can
be harmful to the client-nurse or family-nurse relationship. Option 4 represents a
communication block that denies the client's right to an opinion.
A decision has just been made to give tissue plasminogen activator (t-PA) (Activase) to a client.
The nurse should obtain which supply for standard use as part of safe nursing care related to
this medication?
1. Flashlight
2. Pulse oximeter
3. Suction equipment
4. Occult blood test strips - Answer 4. Occult blood test strips
Activase is a thrombolytic medication that dissolves thrombi or emboli. Bleeding is a frequent
and potentially severe adverse effect of therapy. The nurse assesses for signs of bleeding in
clients receiving this therapy using occult blood test strips to test urine, stool, or nasogastric
drainage. A flashlight is used for pupil assessment as part of the neurological examination in the
Hematological Medications- Test
Questions and Answers Graded A+
2026 Update.
A home care nurse is visiting a client who was discharged to home with a prescription for
continued administration of enoxaparin (Lovenox) subcutaneously. What is the nurse's priority
assessment for this client?
1. Constipation
2. Fear of needles
3. Nausea or vomiting
4. Bleeding gums or bruising - Answer 4. Bleeding gums or bruising
Enoxaparin is an anticoagulant. An adverse effect of anticoagulant therapy is bleeding.
Accordingly, the nurse questions the client about signs and symptoms that could indicate
bleeding, such as bleeding gums, bruising, hematuria, or dark tarry stools.
The nurse is assigned to care for a client who was just admitted to the hospital for the
treatment of iron overload. The nurse anticipates that the health care provider will prescribe
which medication to treat the iron overload?
1. Granisetron
2. Ketoconazole
3. Deferoxamine
4. Terbinafine (Lamisil) - Answer 3. Deferoxamine
Deferoxamine is a medication used to treat iron overload. Granisetron is an antiemetic.
Ketoconazole and terbinafine are antifungal medications.
Epoetin alfa (Epogen, Procrit) has been prescribed for a client with chronic kidney disease who
is being cared for by a nursing student. The nursing instructor determines that the student
understands the procedure for administering the medication when the student states that
which route of administration is acceptable?
1. Oral
2. Z-track
3. Intramuscular
,4. Subcutaneous - Answer 4. Subcutaneous
Epoetin alfa is administered parenterally by the intravenous or subcutaneous route. It cannot be
given orally because it is a glycoprotein and would be degraded in the gastrointestinal tract.
Enoxaparin sodium (Lovenox) is prescribed for a client after hip replacement surgery. What
should the nurse prepare to have available in the event that an overdose of the medication
occurs?
1. Adrenalin
2. Vitamin K
3. Epinephrine
4. Protamine sulfate - Answer 4. Protamine sulfate
Enoxaparin sodium is an anticoagulant. Accidental overdose of this medication may lead to
bleeding complications. The antidote is protamine sulfate. Adrenalin is a trademarked
preparation of epinephrine, which normally is used to treat hypersensitivity reactions or acute
bronchial asthma attacks and bronchospasms. Vitamin K is the antidote for warfarin sodium
(Coumadin).
A client with a subarachnoid hemorrhage needs to have surgery delayed until a stable clinical
condition is achieved. The nurse prepares to administer which medication as prescribed to
prevent clot breakdown and dissolution?
1. Alteplase (Activase)
2. Warfarin (Coumadin)
3. Heparin sodium (Heparin)
4. Aminocaproic acid (Amicar) - Answer 4. Aminocaproic acid (Amicar)
Aminocaproic acid (Amicar) is an antifibrinolytic agent that prevents clot breakdown or
dissolution. It is commonly prescribed after subarachnoid hemorrhage if surgery is delayed or
contraindicated, to prevent further hemorrhage. Alteplase is a fibrinolytic that actively breaks
down clots. Warfarin and heparin sodium are anticoagulants that interfere with propagation or
growth of a clot.
A client is taking ticlopidine hydrochloride (Ticlid). The nurse should tell the client to avoid
which substance while taking this medication?
1. Vitamin C
, 2. Vitamin D
3. Acetaminophen (Tylenol)
4. Acetylsalicylic acid (aspirin) - Answer 4. Acetylsalicylic acid (aspirin)
Ticlopidine hydrochloride is a platelet aggregation inhibitor. It is used to decrease the risk of
thrombotic stroke in clients with precursor symptoms. Because it is an antiplatelet agent, other
medications that precipitate or aggravate bleeding should be avoided during its use. Therefore,
aspirin or any aspirin-containing product should be avoided. The substances in options 1, 2, and
3 are safe to consume.
A client is admitted to the hospital emergency department with an acute anterior wall
myocardial infarction. The nurse discusses streptokinase (Streptase) therapy with the client and
spouse. The spouse is concerned about the dangers of this treatment. Which statement by the
nurse is appropriate?
1. "There is no reason to worry. We use this medication all the time."
2. "I'm certain you made the correct decision to use this medication."
3. "You have concerns about whether this treatment is the best option."
4. "Your loved one is very ill. The health care provider has made the best decision for you." -
Answer 3. "You have concerns about whether this treatment is the best option."
Paraphrasing is restating the client's or family members' own words. This allows the client and
family members to express their concerns and talk through the decisions that have been made.
Option 1 is offering false reassurance. In option 2, the nurse is expressing approval, which can
be harmful to the client-nurse or family-nurse relationship. Option 4 represents a
communication block that denies the client's right to an opinion.
A decision has just been made to give tissue plasminogen activator (t-PA) (Activase) to a client.
The nurse should obtain which supply for standard use as part of safe nursing care related to
this medication?
1. Flashlight
2. Pulse oximeter
3. Suction equipment
4. Occult blood test strips - Answer 4. Occult blood test strips
Activase is a thrombolytic medication that dissolves thrombi or emboli. Bleeding is a frequent
and potentially severe adverse effect of therapy. The nurse assesses for signs of bleeding in
clients receiving this therapy using occult blood test strips to test urine, stool, or nasogastric
drainage. A flashlight is used for pupil assessment as part of the neurological examination in the
