CRNI: Chemotherapy Questions and
Answers Updated 2026
MostMcommonMtypesMofMcancerMforMmenM-MAnswerMLung,Mprostate,Mcolon
MostMcommonMtypesMofMcancerMforMwomenM-MAnswerMLung,Mbreast,Mcolon
irritantM-
MAnswerMaMsubstanceMthatMcausesMinflammationMorMdiscomfortMbutMnoMnecrosis
combinationMtherapyM-
MAnswerMTheMadministrationMofMtwoMorMmoreMchemoMmedicationsMsimultaneouslyMtoM
achieveMbetterMoutcomes,MuseMlessMofMeachMchemoMagentMtoMachieveMdesiredMresults,
MreduceMsideMeffects,MreduceMresistanceMtoMagents
CombinationMchemotherapyMprotocols:MCHOPM-MAnswerMForMnon-
hodgkinsMlymphoma;MCyclophosphamide,Mdoxorubicin,Mvincristine,M&Mprednisone
CombinationMchemotherapyMprotocols:MFAMM-
MAnswerMForMpancreaticMca;Mfluorouracil,Mdoxorubicin,M&Mmitomycin
CombinationMchemotherapyMprotocol:MMOPPM-
MAnswerMForMlymphoma,MHodgkin'sMdisease.MMechlorethanine,Mvincristine,Mprocarbazine,
M&Mprednisone.
CombinationMchemotherapyMprotocol:MVADM-
MAnswerMForMmultipleMmyeloma.Mvincristine,Mdoxorubicin,M&Mdexamethasone.
VincaMPlantMAlkaloidsM(M-phaseMcellMcycleMspecific)M-
MAnswerMVincristine,Mvinblastine,Metoposide,Mteniposide
AntimetabolitesM(s-phaseMcellMcycleMspecific)M-MAnswerM5-Fu,Mmethotrexate
NitrosoureasM-MAnswerMOnlyMagentMthatMwillMcrossMtheMbloodMbrainMbarrier
, MethotrexateMsideMeffectsM-MAnswerMStomatitis,Mnephrotoxicity,MulcersMinMmouth
UseMofMleucovorinM12-
24MhoursMafterMthisMdrugMasMantidoteMtoMboneMmarrowMtoxicity,MtoM'rescue'MboneM
marrowM-MAnswerMMethotrexate
ThisMdrugMmayMcauseM'radiationMrecall'Mand/orMphotosensitivityMwhereManMareaMofMpr
eciousMradiationMexposureMwillMturnMredM-MAnswerMMethotrexate
ThisMagentMmayMonlyMbeMadministeredMintraarteriallyM-MAnswerMFloxuridine
MayMbeMgivenMIVMorMintrathecal,MsideMeffectsMoccurringM6-
12MhrsMafterMadministrationM-MAnswerMCytarabine
DOMNOTMgiveMallopurinolMwithMthisMchemoMagentM-MAnswerMFluorouracilMakaM5MFU
SideMeffectsMofMfluorouracil/M5MFUM-
MAnswerMCharcoalMgray/hyperMpigmentationMofMveinsMandMnails,Mdiarrhea,MparesthesiaM
dueMtoMperipheralMnerveMdamage
ThisMdrugMmustMbeMadministeredMwithinM1MhourMandMsideMeffectsMincludeMpancytopen
iaM-MAnswerMGemcitabine
Pre-
medicateMwithMdecadronM4mgMPO,M1MdayMbeforeMthisMdrugMtoMdecreaseMdermatologic
MtoxicityM-MAnswerMPemetrexed
MonitorMliverMandMkidneyMfunctionMcloselyMwithMthisMchemoMagentM-
MAnswerMPemetrexed
TheseMchemoMagentsMmayMcauseMextremeMconstipationMandMperipheralMneuropathy.MHyl
enexMandMheatMshouldMbeMusedMforMextravasationM-
MAnswerMVincristineMandMvinblastine
ExtremeMhypotensionMmayMoccurMwithMrapidMadministrationMofMthisMagentM-
MAnswerMEtoposideM(VP16)
Answers Updated 2026
MostMcommonMtypesMofMcancerMforMmenM-MAnswerMLung,Mprostate,Mcolon
MostMcommonMtypesMofMcancerMforMwomenM-MAnswerMLung,Mbreast,Mcolon
irritantM-
MAnswerMaMsubstanceMthatMcausesMinflammationMorMdiscomfortMbutMnoMnecrosis
combinationMtherapyM-
MAnswerMTheMadministrationMofMtwoMorMmoreMchemoMmedicationsMsimultaneouslyMtoM
achieveMbetterMoutcomes,MuseMlessMofMeachMchemoMagentMtoMachieveMdesiredMresults,
MreduceMsideMeffects,MreduceMresistanceMtoMagents
CombinationMchemotherapyMprotocols:MCHOPM-MAnswerMForMnon-
hodgkinsMlymphoma;MCyclophosphamide,Mdoxorubicin,Mvincristine,M&Mprednisone
CombinationMchemotherapyMprotocols:MFAMM-
MAnswerMForMpancreaticMca;Mfluorouracil,Mdoxorubicin,M&Mmitomycin
CombinationMchemotherapyMprotocol:MMOPPM-
MAnswerMForMlymphoma,MHodgkin'sMdisease.MMechlorethanine,Mvincristine,Mprocarbazine,
M&Mprednisone.
CombinationMchemotherapyMprotocol:MVADM-
MAnswerMForMmultipleMmyeloma.Mvincristine,Mdoxorubicin,M&Mdexamethasone.
VincaMPlantMAlkaloidsM(M-phaseMcellMcycleMspecific)M-
MAnswerMVincristine,Mvinblastine,Metoposide,Mteniposide
AntimetabolitesM(s-phaseMcellMcycleMspecific)M-MAnswerM5-Fu,Mmethotrexate
NitrosoureasM-MAnswerMOnlyMagentMthatMwillMcrossMtheMbloodMbrainMbarrier
, MethotrexateMsideMeffectsM-MAnswerMStomatitis,Mnephrotoxicity,MulcersMinMmouth
UseMofMleucovorinM12-
24MhoursMafterMthisMdrugMasMantidoteMtoMboneMmarrowMtoxicity,MtoM'rescue'MboneM
marrowM-MAnswerMMethotrexate
ThisMdrugMmayMcauseM'radiationMrecall'Mand/orMphotosensitivityMwhereManMareaMofMpr
eciousMradiationMexposureMwillMturnMredM-MAnswerMMethotrexate
ThisMagentMmayMonlyMbeMadministeredMintraarteriallyM-MAnswerMFloxuridine
MayMbeMgivenMIVMorMintrathecal,MsideMeffectsMoccurringM6-
12MhrsMafterMadministrationM-MAnswerMCytarabine
DOMNOTMgiveMallopurinolMwithMthisMchemoMagentM-MAnswerMFluorouracilMakaM5MFU
SideMeffectsMofMfluorouracil/M5MFUM-
MAnswerMCharcoalMgray/hyperMpigmentationMofMveinsMandMnails,Mdiarrhea,MparesthesiaM
dueMtoMperipheralMnerveMdamage
ThisMdrugMmustMbeMadministeredMwithinM1MhourMandMsideMeffectsMincludeMpancytopen
iaM-MAnswerMGemcitabine
Pre-
medicateMwithMdecadronM4mgMPO,M1MdayMbeforeMthisMdrugMtoMdecreaseMdermatologic
MtoxicityM-MAnswerMPemetrexed
MonitorMliverMandMkidneyMfunctionMcloselyMwithMthisMchemoMagentM-
MAnswerMPemetrexed
TheseMchemoMagentsMmayMcauseMextremeMconstipationMandMperipheralMneuropathy.MHyl
enexMandMheatMshouldMbeMusedMforMextravasationM-
MAnswerMVincristineMandMvinblastine
ExtremeMhypotensionMmayMoccurMwithMrapidMadministrationMofMthisMagentM-
MAnswerMEtoposideM(VP16)
