NR 546- Final Study Guide 5-8
Questions with Correct ANSWERS |
Latest Update 100% PASS
Prefrontal Cortex Symptoms of MDD - CORRECT ANSWER-Concentration
Mental Fatigue
Mood
PFC & Amygdala Symptoms of MDD - CORRECT ANSWER-Guilt
Suicidality
Worthlessness
Striatum Symptoms of MDD - CORRECT ANSWER-Physical fatigue
Nucleus Accumbens Symptoms of MDD - CORRECT ANSWER-Pleasure
interests
Hypothalamus Symptoms of MDD - CORRECT ANSWER-Sleep
Appetite
Thalamus & Hypothalamus Symptoms of Mania - CORRECT ANSWER-
Decreased sleep/arousal
,Striatum Symptoms of Mania - CORRECT ANSWER-Motor/agitation
Prefrontal cortex (PFC) Symptoms of Mania - CORRECT ANSWER-Risk-taking
Talkative/pressured speech
Nucleus Accumbens & PFC Symptoms of Mania - CORRECT ANSWER-Racing
thoughts, grandiosity
PFC & Amygdala Symptoms of Mania - CORRECT ANSWER-Mood
Medication Management - CORRECT ANSWER-SSRI-Selective Serotonin
Reuptake Inhibitors
*Inhibit 5 HT reuptake
SNRI-Serotonin Norepinephrine Reuptake Inhibitors
*inhibit 5-HT reuptake
*inhibit NE reuptake (increase energy, focus)
*increase DA in prefrontal cortex (increase cognition)
NDRI-Norepinephrine Dopamine Reuptake inhibitors
*inhibit DA reuptake (increase alertness, motivation)
*inhibit NE reuptake (increase energy)
SARI-Serotonin Antagonist Reuptake Inhibitors
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,Selective Serotonin Reuptake Inhibitors (SSRIs): Most adverse effects will subside
after 4-5 days once the body adjusts to increased serotonin levels. - CORRECT
ANSWER-diarrhea
headache
weight gain
sexual side effects
Serotonin Norepinephrine Reuptake Inhibitors (SNRIs): Medications should not
be abruptly stopped to avoid discontinuation symptoms. NE effects of the
medication may increase anxiety in some clients. Report worsening anxiety to the
provider. - CORRECT ANSWER-elevated blood pressure
anxiety
insomnia
constipation
Norepinephrine Dopamine Reuptake Inhibitors (NDRI): Take medication in the
morning. Stop taking medication if seizures occur. Stop taking medication if
anxiety is noted. - CORRECT ANSWER-agitation
headache
dry mouth
constipation
, weight loss
escitalopram (Lexapro) SSRI - CORRECT ANSWER-no known drug interactions
best tolerated SSRI
27-32 hour half-life good for forgetful prone clients
least CYP reactions
Substrate for 3A4
citalopram (Celexa) SSRI - CORRECT ANSWER-mild antihistamine effects; Half-
Life: 23-45 hours
Weak Inhibitor of 2D6
fluoxetine (Prozac) SSRI - CORRECT ANSWER-longest half-life
Use caution in patients with comorbid anxiety due to risk for activation and panic
attacks
Half-Life: 2-3 days parent, 2 week metabolite
Inhibits 2D6 and 3A4
paroxetine (Paxil) SSRI - CORRECT ANSWER-also treats social anxiety and
insomnia
associated with weight gain
will experience withdrawal with missed dose or abrupt stop
© 2026 Copyright. All Rights Reserved. This document is
protected by copyright law
Questions with Correct ANSWERS |
Latest Update 100% PASS
Prefrontal Cortex Symptoms of MDD - CORRECT ANSWER-Concentration
Mental Fatigue
Mood
PFC & Amygdala Symptoms of MDD - CORRECT ANSWER-Guilt
Suicidality
Worthlessness
Striatum Symptoms of MDD - CORRECT ANSWER-Physical fatigue
Nucleus Accumbens Symptoms of MDD - CORRECT ANSWER-Pleasure
interests
Hypothalamus Symptoms of MDD - CORRECT ANSWER-Sleep
Appetite
Thalamus & Hypothalamus Symptoms of Mania - CORRECT ANSWER-
Decreased sleep/arousal
,Striatum Symptoms of Mania - CORRECT ANSWER-Motor/agitation
Prefrontal cortex (PFC) Symptoms of Mania - CORRECT ANSWER-Risk-taking
Talkative/pressured speech
Nucleus Accumbens & PFC Symptoms of Mania - CORRECT ANSWER-Racing
thoughts, grandiosity
PFC & Amygdala Symptoms of Mania - CORRECT ANSWER-Mood
Medication Management - CORRECT ANSWER-SSRI-Selective Serotonin
Reuptake Inhibitors
*Inhibit 5 HT reuptake
SNRI-Serotonin Norepinephrine Reuptake Inhibitors
*inhibit 5-HT reuptake
*inhibit NE reuptake (increase energy, focus)
*increase DA in prefrontal cortex (increase cognition)
NDRI-Norepinephrine Dopamine Reuptake inhibitors
*inhibit DA reuptake (increase alertness, motivation)
*inhibit NE reuptake (increase energy)
SARI-Serotonin Antagonist Reuptake Inhibitors
© 2026 Copyright. All Rights Reserved. This document is
protected by copyright law
,Selective Serotonin Reuptake Inhibitors (SSRIs): Most adverse effects will subside
after 4-5 days once the body adjusts to increased serotonin levels. - CORRECT
ANSWER-diarrhea
headache
weight gain
sexual side effects
Serotonin Norepinephrine Reuptake Inhibitors (SNRIs): Medications should not
be abruptly stopped to avoid discontinuation symptoms. NE effects of the
medication may increase anxiety in some clients. Report worsening anxiety to the
provider. - CORRECT ANSWER-elevated blood pressure
anxiety
insomnia
constipation
Norepinephrine Dopamine Reuptake Inhibitors (NDRI): Take medication in the
morning. Stop taking medication if seizures occur. Stop taking medication if
anxiety is noted. - CORRECT ANSWER-agitation
headache
dry mouth
constipation
, weight loss
escitalopram (Lexapro) SSRI - CORRECT ANSWER-no known drug interactions
best tolerated SSRI
27-32 hour half-life good for forgetful prone clients
least CYP reactions
Substrate for 3A4
citalopram (Celexa) SSRI - CORRECT ANSWER-mild antihistamine effects; Half-
Life: 23-45 hours
Weak Inhibitor of 2D6
fluoxetine (Prozac) SSRI - CORRECT ANSWER-longest half-life
Use caution in patients with comorbid anxiety due to risk for activation and panic
attacks
Half-Life: 2-3 days parent, 2 week metabolite
Inhibits 2D6 and 3A4
paroxetine (Paxil) SSRI - CORRECT ANSWER-also treats social anxiety and
insomnia
associated with weight gain
will experience withdrawal with missed dose or abrupt stop
© 2026 Copyright. All Rights Reserved. This document is
protected by copyright law
