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Summary

Summary Life Sciences Grade 12 IEB

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This is a summary of the Life Sciences Mind Action Series textbook for the Grade 12 IEB Syllabus

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CHROMOSOMES AND MEIOSIS

CHROMOSOMES:

Long thread-like structures → form part of chromatin network in nuclei of
cells

● Absorb dye easily -- why called chromosomes (colored bodies)
● Visible under microscope - only seen as individual threads when cell
dividing



IN SOMATIC (BODY) CELLS:


● Number of cells is same
● Chromosomes made up of 2 sets: 1 from mother (maternal) & 1 from father
(paternal) = ​Diploid cells​ (x2) / 2n
● For each paternal chromosomes there's matching maternal chromosome
forming = ​Homologous Pair ​(same size, shape and have same genes in same
place but alleles for each trait may not be same)
● DNA of each chromosome replicates to form 2 identical threads /
chromatids joined by ​centromere​ ---> takes place during ​interphase
(i.e. between cell division. Threads only become visible when they
shorten and thicken as cell divides)
● Replication of DNA is NB to ensure that as cell divides each daughter
cell receives full complement of all genetic material.


WHAT IS MEANT BY CHROMOSOME NUMBER ?
● Each species has a specific number of chromosomes in its somatic cells →
its the similarities in DNA of chromosomes that their show relationships
not number.

, MEIOSIS:

WHAT IS MEIOSIS?

● Cell division that takes place in reproductive organs to produce gametes
(sex cells) in animals and plants (spores)
● In meiosis - number of chromosomes is reduced from 2 sets (2n) in parent
cell to 1 set (n) in each daughter cell formed (i.e. number of
chromosomes is halved)
● Gametes / spores formed are called ​haploid ​- only have one set of
chromosomes (i.e. 1 chromosomes from each homologous pair)
○ In sexual reproduction a male haploid gamete fuses with a female
haploid gamete during ​fertilisation​ to form a ​diploid zygote



WHERE DOES MEIOSIS TAKE PLACE?
Animals = testis and ovaries

● Formation of sperm cells in testis → spermatogenesis
● Formation of egg cells in ovaries → oogenesis



THE PROCESS OF MEIOSIS:
DNA of parent cells is replicated in interphase leading up to both mitosis and
meiosis

In meiosis - replication followed by 2 divisions

Meiosis 1 → reduction division

● Results in 2 cells being formed each with half number of chromosomes of
parent cell (i.e. haploid (n) number )

Meiosis 2 → copying division

● 2​ haploid cells formed - each dividing again by mitosis to form ​4
haploid cells

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