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Summary Process of protein synthesis - Grade 12 CAPS

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My name is Abigail and i am a 2024 matriculant (CAPS) with multiple distinctions, i have uploaded various documents, this one included, to assist others to achieve their goals through pre-summarized and easy to understand notes. A summary on protein synthesis, breaking down the processes and steps of transcription and translation.

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Uploaded on
February 21, 2025
Number of pages
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Written in
2024/2025
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Summary

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Protein Synthesis: k
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Terminology: U


 Protein Synthesis = the process of making proteins in cells. It involves copying genetic
y
b
information from DNA to RNA, and then using this information to build proteins.
 Transcription = the process by which DNA makes and codes mRNA.
 mRNA = messenger RNA
 ribosome = organelle where proteins are produced
 Translation = process by which a specific protein is formed from a chain of amino
acids due to the sequence of codons in the mRNA which was coded during
transcription.
 Gene = a section of DNA

Transcription:
 Occurs in the nucleus
 Starts when a gene unwinds and unzips as the weak hydrogen bonds between the
nitrogenous bases break via enzymes
 Only one of the DNA strands are used as a template
 Free floating mRNA codons in the nucleus pair up with a DNA triplet, that has its
complimentary bases on the DNA strand acting as a template
 The mRNA codons join up (phosphate to ribose sugar) to form a strand of mRNA
 The DNA has now transcribed its genetic code to the mRNA which breaks away and
the DNA re-zips
 The mRNA leaves the nucleus through pores in the nuclear membrane and carries
the genetic code to the ribosomes

Translation:
 Occurs on the ribosomes in cytoplasm
 The mRNA is the template that determines the order in which the amino acids are
linked
 tRNA nucleotides are found in the cytoplasm of the cell and have 3 bases called anti-
codons
 The tRNA links up with a specific amino acid in the cytoplasm which is determined by
the anti-codon
 The tRNA brings its amino acid to the ribosome where the anti-codon links with its
complimentary mRNA codon
 The amino acid is released from the tRNA anti-codon and links up with the adjacent
amino acid by means of a peptide bond
 The tRNA molecule is also released and leaves the ribosomes…a new tRNA enters the
ribosome
 At the end, a stop codon signals that the protein chain is complete
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I am a 2024 matriculant with multiple distinctions and this store is to provide others with notes and summaries I created that helped me achieve my goals! I upload a variety of subjects ♡

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