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Summary Gastrointestinal tract drugs explained

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2014/2015 Written for academic year
Institution University Of Pretoria (UP)
Course Pharmacology
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I want to help you get through all the different drug classes in Pharmacology. I have found that students struggle to get through the amount of work. These summaries helped me get through my Honours Degree. I will soon graduate with my Masters of Science in Neurogenetics. You got this!

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PRINCIPLES OF DRUG ACTION

NON-SPECIFIC DRUG ACTION
 By virtue of their physicochemical properties
 Activated charcoal
 Osmotic diuretics
FALSE SUBSTRATES/INHIBITORS FOR CERTAIN
TRANSPORT SYSTEMS
 Ion channels
 Ca2+ = calcium channel blockers
 Na+ = local anesthetics
 KATP = oral antidiabetics
 Active transport
 Na+/K+-ATPase = cardiac glycosides

ENZYME INHIBITORS
 Acetylcholinesterase
 HMG-CoA reductase
 MAO
 COX
 Thymidine kinase
 Carbonic anhydrase(diuretics)




ACTING ON SPECIFIC PROTEIN MOLECULES (Rs)
 MOST drugs
 Proteins are located in the cell membrane
 Rs respond to endogenous chemicals
Connected book
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Humphrey Rang, James M. Ritter Rang & Dale\'s Pharmacology
Publisher: januari 2015 ISBN: 9780702053627 Edition: 1

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