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Summary Life at Molecular Level - Grade 12 biology

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A detailed summary of entire Life at molecular level including DNA, DNA replication, RNA vs DNA, protein synthesis, Gene mutations, detailed table on Meiosis, Monohybrid crosses. Grade 12 Biology.

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Uploaded on
May 30, 2022
Number of pages
15
Written in
2021/2022
Type
Summary

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Lifer at molecular level

DNA - deoxyribonucleic acid
- Carries hereditary information
- Enables growth by coding for protein synthesis
- Can replicate during mitosis

Where is DNA found
- Mainly in the nucleus : forms part of chromosomes that make up chromatin network
- Chromatin - chromosomal material made up of DNA, RNA and histone proteins
- DNA molecule = coiled up so that long structures can fit inside the nucleus
- 2 metres of DNA coiled in single cell

Extranuclear DNA
- Small amounts of DNA found outside nucleus inside mitochondria

How is DNA made up
- Long twisted ladder
- Two strands twist to form stable, 3D double helix




What units make up DNA
- DNA molecule is a long chain (polymer) made up of smaller units (monomers)
- Building blocks called nucleotides, each one made up of :
- Sugar molecule - deoxyribose (S)
- Phosphate molecule (P)
- Nitrogenous base :
- Adenine (A)
- Thymine (T)
- Guanine (G)
- Cytosine (C)

, How is double helix made up
- Outer two strands of the ladder are formed by a chain of alternating sugar and
phosphate links
- the rungs of the ladder are formed from pairs of bases linked by weak hydrogen
bonds
- the base pairs are attached to the sugar molecules

How do these four base pairs link up
- Adenine only bonds w thiamine : DOUBLE hydrogen bond
- Cytosine will only bond with guanine : TRIPLE hydrogen bond

How are base pairs classified
Purines Pyrimidines

Made up of 2 fused rings of nitrogen, Made up of one ring of similar atoms,
carbon and hydrogen atoms therefore - much smaller
Ex : G & A Ex : T, C & U


What is the role of DNA
- Carry hereditary information in each cell in the form of genes
- Provide a blueprint for an organism's growth and development by coding for protein
synthesis
- Can make a copy of itself so that a copy of genetic information is passed on to each
daughter cell - genetic code passed on from generation to generation

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