NSG 552 Psychopharmacology Exam 2
2026/2027 | Practice Questions & Answers
with Rationales | Latest Update
The rate-limiting enzyme in the synthesis of catecholamines is
a. Tyrosine hydroxylase
b. aromatic acid decarboxylase
c. dopamine B- hydroxlase
d. DOPA - correct answer-a. Tryosine hydroxylase
2. Activation of terminal autoreceptors inhibits dopamine release by
a. increasing Cl- entry into the terminal.
b. decreasing Ca2+ entry into the terminal.
c. preventing reuptake into vesicles.
d. decreasing Na+ entry into the terminal. - correct answer-B. Decreasing Ca 2+
entry into the terminal
3. _______ and _______ exert their pharmacological effects by blocking
monoamine reuptake.
a. Cocaine; phenelzine
b. Cocaine; tricyclic antidepressants
,c. Clonidine; tricyclic antidepressants
d. Clonidine; yohimbine - correct answer-B. Cocaine; tricyclic antidepressants
4. The dopamine pathway most important for regulating movement is the
_______ pathway.
a. nigrostriatal
b. mesocortical
c. mesolimbic
d. tuberohypophyseal - correct answer-A. Nigrostriatal
5. A commonly used dopamine receptor agonist is _______, which is now being
used to treat _______.
a. apomorphine; schizophrenia
b. apomorphine; erectile dysfunction
c. haloperidol; cocaine addiction
d. quinpirole; schizophrenia - correct answer-B. haloperidol; cocaine addiction
6. Dopaminergic cell bodies are found primarily in the _______, while adrenergic
cell bodies are found in the _______.
a. midbrain; pons and medulla
b. midbrain; hypothalamus
c. pons and medulla; forebrain
d. frontal cortex; cerebellum - correct answer-A. midbrain; pons and medulla
7. B1- and B2-adrenoceptors _______ while B2-receptors _______.
, a. stimulate adenylyl cyclase; enhance free Ca++ levels
b. inhibit adenylyl cyclase; stimulate adenylyl cyclase
c. stimulate adenylyl cyclase; inhibit adenylyl cyclase
d. increase K+ channel opening; inhibit adenylyl cyclase - correct answer-c.
stimulate adenylyl cyclase; inhibit adenylyl cyclase
8. In the treatment of hypertension, prazosin _______, while propranolol
_______.
a. blocks alpha1-receptors and causes dilation of blood vessels; blocks beta-
receptors in the heart and decreases the contractile force
b. blocks alpha 1-receptors and causes constriction of blood vessels; activates
beta -receptors in the heart and increases the contractile force
c. activates alpha 1-receptors and causes dilation of blood vessels; activates beta-
receptors in the heart and decreases the contractile force
d. activates alpha 1-receptors and causes constriction of blood vessels; blocks
beta-receptors in the heart and increases the contractile force - correct answer-a.
blocks alpha 1-receptors and causes dilation of blood vessels; blocks beta-
receptors in the heart and decreases the contractile force
9. What type of meal is most likely to increase brain levels of serotonin in
animals?
a. High carbohydrate, high protein
b. High carbohydrate, low protein
2026/2027 | Practice Questions & Answers
with Rationales | Latest Update
The rate-limiting enzyme in the synthesis of catecholamines is
a. Tyrosine hydroxylase
b. aromatic acid decarboxylase
c. dopamine B- hydroxlase
d. DOPA - correct answer-a. Tryosine hydroxylase
2. Activation of terminal autoreceptors inhibits dopamine release by
a. increasing Cl- entry into the terminal.
b. decreasing Ca2+ entry into the terminal.
c. preventing reuptake into vesicles.
d. decreasing Na+ entry into the terminal. - correct answer-B. Decreasing Ca 2+
entry into the terminal
3. _______ and _______ exert their pharmacological effects by blocking
monoamine reuptake.
a. Cocaine; phenelzine
b. Cocaine; tricyclic antidepressants
,c. Clonidine; tricyclic antidepressants
d. Clonidine; yohimbine - correct answer-B. Cocaine; tricyclic antidepressants
4. The dopamine pathway most important for regulating movement is the
_______ pathway.
a. nigrostriatal
b. mesocortical
c. mesolimbic
d. tuberohypophyseal - correct answer-A. Nigrostriatal
5. A commonly used dopamine receptor agonist is _______, which is now being
used to treat _______.
a. apomorphine; schizophrenia
b. apomorphine; erectile dysfunction
c. haloperidol; cocaine addiction
d. quinpirole; schizophrenia - correct answer-B. haloperidol; cocaine addiction
6. Dopaminergic cell bodies are found primarily in the _______, while adrenergic
cell bodies are found in the _______.
a. midbrain; pons and medulla
b. midbrain; hypothalamus
c. pons and medulla; forebrain
d. frontal cortex; cerebellum - correct answer-A. midbrain; pons and medulla
7. B1- and B2-adrenoceptors _______ while B2-receptors _______.
, a. stimulate adenylyl cyclase; enhance free Ca++ levels
b. inhibit adenylyl cyclase; stimulate adenylyl cyclase
c. stimulate adenylyl cyclase; inhibit adenylyl cyclase
d. increase K+ channel opening; inhibit adenylyl cyclase - correct answer-c.
stimulate adenylyl cyclase; inhibit adenylyl cyclase
8. In the treatment of hypertension, prazosin _______, while propranolol
_______.
a. blocks alpha1-receptors and causes dilation of blood vessels; blocks beta-
receptors in the heart and decreases the contractile force
b. blocks alpha 1-receptors and causes constriction of blood vessels; activates
beta -receptors in the heart and increases the contractile force
c. activates alpha 1-receptors and causes dilation of blood vessels; activates beta-
receptors in the heart and decreases the contractile force
d. activates alpha 1-receptors and causes constriction of blood vessels; blocks
beta-receptors in the heart and increases the contractile force - correct answer-a.
blocks alpha 1-receptors and causes dilation of blood vessels; blocks beta-
receptors in the heart and decreases the contractile force
9. What type of meal is most likely to increase brain levels of serotonin in
animals?
a. High carbohydrate, high protein
b. High carbohydrate, low protein
