NSG 552 Psychopharmacology Exam 1 (Latest
2026 Update) Questions and Verified Answers |
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Terms in this set (205)
Pharmacokinetics Studies how the body acts on the drug
Pharmacodynamics Studies how the drug acts on the body
First-generation antipsychotic - first developed in the 1950s, first available
treatment for psychosis
- aka typical antipsychotics
- increased risk for EPS, Tardive dyskinesia
- d2 blocker
- Currently 11 FDA-approved and commerically
available FGAs
- Most common differences between individual
FGAs are their potency and side effects
- examples include Thorazine (chlorpromazine),
Haldol (haloperidol), Prolixin (fluphenazine),
perphenazine (Trilafon
, Second-generation antipsychotic - examples include Abilify (aripiprazole), Seroquel
(quetiapine), Zyprexa (olanzapine), Risperdal
(risperidone), Clozaril (clozapine)
- lower risk of EPS symptoms compared to 1st gen
- higher risk of metabolic side effects
- serotonin-dopamine receptor antagonists
- AKA atypical antipsychotics
EPS Involuntary movements that occur as a side effect to
certina medications. AKA drug induced movement
disorder. May include tardive dyskinesia, dystonic
reactions, parkinsons-like symptoms, akathesia,
NMD, akinesia
- Can be acute or chronic
- related to suppression of D2 dopamine receptors
in the nigrostriatal pathway
Tardive dyskinesia - characterized by involuntary movments in the face
and body
- often induced by long-term use of anitpsychotic
drugs
- can be associated with use of other medication
types (antidepressants, lithium, antihistamines)
- more common with 1st gen antipsychotics
- movements may include: writhing, mouth
puckering, tongue rolling, lip smacking, pill rolling,
tongue protrusion
Upregulation Refers to the activiation of the nervous system. Is
the process by which a cell increases its response to
a subtance or signal from outside the cell to carry
out a specific response
downregulation Refers to state of calm/relation within nervous
system. Characterized by a decreased response by
a cell to a molecule or neurotransmitter.
2026 Update) Questions and Verified Answers |
100% Correct | Grade A+
Play your way to mastery with fun games
Match Blocks Charms NEW
Terms in this set (205)
Pharmacokinetics Studies how the body acts on the drug
Pharmacodynamics Studies how the drug acts on the body
First-generation antipsychotic - first developed in the 1950s, first available
treatment for psychosis
- aka typical antipsychotics
- increased risk for EPS, Tardive dyskinesia
- d2 blocker
- Currently 11 FDA-approved and commerically
available FGAs
- Most common differences between individual
FGAs are their potency and side effects
- examples include Thorazine (chlorpromazine),
Haldol (haloperidol), Prolixin (fluphenazine),
perphenazine (Trilafon
, Second-generation antipsychotic - examples include Abilify (aripiprazole), Seroquel
(quetiapine), Zyprexa (olanzapine), Risperdal
(risperidone), Clozaril (clozapine)
- lower risk of EPS symptoms compared to 1st gen
- higher risk of metabolic side effects
- serotonin-dopamine receptor antagonists
- AKA atypical antipsychotics
EPS Involuntary movements that occur as a side effect to
certina medications. AKA drug induced movement
disorder. May include tardive dyskinesia, dystonic
reactions, parkinsons-like symptoms, akathesia,
NMD, akinesia
- Can be acute or chronic
- related to suppression of D2 dopamine receptors
in the nigrostriatal pathway
Tardive dyskinesia - characterized by involuntary movments in the face
and body
- often induced by long-term use of anitpsychotic
drugs
- can be associated with use of other medication
types (antidepressants, lithium, antihistamines)
- more common with 1st gen antipsychotics
- movements may include: writhing, mouth
puckering, tongue rolling, lip smacking, pill rolling,
tongue protrusion
Upregulation Refers to the activiation of the nervous system. Is
the process by which a cell increases its response to
a subtance or signal from outside the cell to carry
out a specific response
downregulation Refers to state of calm/relation within nervous
system. Characterized by a decreased response by
a cell to a molecule or neurotransmitter.
