Maryville NURS 615 Exam 1 Maryville University of Saint Louis | Questions
with 100% Verified Answers | Latest Update
Question: NP prescriptive authority is regulated by
Answer:
the state board of nursing
Question: Criteria for choosing an effective drug for a disorder
Answer:
Consulting nationally recognized guidelines for disease management
Question: Hypoalbuminemia affects the process of prescribing because
Answer:
it increases the free drug floating around and could cause toxicity or different effects
Question: Hypoalbuminemia
Answer:
affects the distribution of the drug to target tissue
Question: Drugs with high first pass metabolism
Answer:
are rapidly metabolized by the liver and may have little or if any desired action. Fraction of drug lost
through the process of absorption.
Question: First pass metabolism
Answer:
The rapid uptake and metabolism of an active compound into inactive compounds by the liver,
immediately after enteric absorption and before it reaches the systemic circulation.
Question: Half-life
Answer:
the amount of time it takes for an administered drug to be half-way cleared from the system
Question: Loading dose
Answer:
drugs with a long half life start with this to achieve desired clinical effects more quickly. Ex:
azithromycin requires the first days dose to be twice that of the other 4 days
, Question: Onset of action
Answer:
The point in time on the drug concentration curve that indicates the first sign of a therapeutic effect
Question: Peak of action
Answer:
The time between drug administration and the maximum concentration of a drug in the blood stream
Question: Peak and trough levels
Answer:
This is used to determine if a drug is in a therapeutic range
Question: Steady-state
Answer:
Amount of drug needed in the body remains constant
Question: IV administration
Answer:
Does not involve absorption and there is no loss of the drug; distribution throughout the body begins
immediately
Question: CYPs
Answer:
are major enzymes that are involved in drug metabolism. They account for nearly 75% of the total
metabolism.
Question: Drugs that utilize the CYP3A4 isoenzymes for metabolism
Answer:
may induce the metabolism of another drug or inhibit the metabolism of another drug
Question: CYP450
Answer:
is the reason behind drug interaction and the rationale of why drugs affect different people in different
ways
Question: Grapefruit
Answer:
reduces the clearance of simvastatin, increasing the risk of myopathy
with 100% Verified Answers | Latest Update
Question: NP prescriptive authority is regulated by
Answer:
the state board of nursing
Question: Criteria for choosing an effective drug for a disorder
Answer:
Consulting nationally recognized guidelines for disease management
Question: Hypoalbuminemia affects the process of prescribing because
Answer:
it increases the free drug floating around and could cause toxicity or different effects
Question: Hypoalbuminemia
Answer:
affects the distribution of the drug to target tissue
Question: Drugs with high first pass metabolism
Answer:
are rapidly metabolized by the liver and may have little or if any desired action. Fraction of drug lost
through the process of absorption.
Question: First pass metabolism
Answer:
The rapid uptake and metabolism of an active compound into inactive compounds by the liver,
immediately after enteric absorption and before it reaches the systemic circulation.
Question: Half-life
Answer:
the amount of time it takes for an administered drug to be half-way cleared from the system
Question: Loading dose
Answer:
drugs with a long half life start with this to achieve desired clinical effects more quickly. Ex:
azithromycin requires the first days dose to be twice that of the other 4 days
, Question: Onset of action
Answer:
The point in time on the drug concentration curve that indicates the first sign of a therapeutic effect
Question: Peak of action
Answer:
The time between drug administration and the maximum concentration of a drug in the blood stream
Question: Peak and trough levels
Answer:
This is used to determine if a drug is in a therapeutic range
Question: Steady-state
Answer:
Amount of drug needed in the body remains constant
Question: IV administration
Answer:
Does not involve absorption and there is no loss of the drug; distribution throughout the body begins
immediately
Question: CYPs
Answer:
are major enzymes that are involved in drug metabolism. They account for nearly 75% of the total
metabolism.
Question: Drugs that utilize the CYP3A4 isoenzymes for metabolism
Answer:
may induce the metabolism of another drug or inhibit the metabolism of another drug
Question: CYP450
Answer:
is the reason behind drug interaction and the rationale of why drugs affect different people in different
ways
Question: Grapefruit
Answer:
reduces the clearance of simvastatin, increasing the risk of myopathy
