EXAM 2
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,NUR 376 • EXAM 2 APPLIED PATHOPHYSIOLOGY
Concordia University
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Table of Contents
NUR 376 EXAM 2...........................................................2
NUR 376 EXAM 2 STUDY GUIDE...............................25
NUR 376 EXAM 2
1. A patient with advanced liver failure has presented with edema. Which of
the following likely played a role in this development?
a. Excess clotting factors
b. Decreased capillary permeability
c. Hypoalbuminemia
d. Hypovolemic hypernatremia
Correct Answer: c. Hypoalbuminemia
Rationale:
The liver synthesizes albumin, the primary plasma protein responsible for
maintaining oncotic pressure. In advanced liver failure, albumin production drops
significantly (hypoalbuminemia), reducing plasma oncotic pressure and allowing
fluid to shift into interstitial spaces, resulting in edema. Excess clotting factors (a) is
incorrect because liver failure typically causes decreased clotting factor synthesis.
, Decreased capillary permeability (b) would reduce edema formation, not increase
it. Hypovolemic hypernatremia (d) is unrelated to the pathophysiology of liver
failure edema.
2. Which of the following is true regarding pancreatic cancer?
a. Identified with alpha-fetoprotein (AFP) marker
b. High survival rate
c. Jaundice is often the first sign
d. Presents with severe acute symptoms
Correct Answer: c. Jaundice is often the first sign
Rationale:
Pancreatic cancer, particularly tumors in the head of the pancreas, frequently
obstruct the common bile duct early in the disease course, causing painless
jaundice as an initial presenting symptom. AFP (a) is a marker for hepatocellular
carcinoma, not pancreatic cancer (CA 19-9 is the typical tumor marker). Pancreatic
cancer has one of the lowest survival rates among malignancies (b), and it typically
presents with insidious, nonspecific symptoms rather than severe acute
manifestations (d).
3. A nurse is explaining how problems in the liver can result in vomiting of
blood. Please place the following in the proper sequence.
a. Portal hypertension
b. Blood backs up in esophageal vein
c. Esophageal varices rupture
d. Blood appears in vomitus
e. Cirrhosis of the liver
Correct Answer:
1. e. Cirrhosis of the liver
2. a. Portal hypertension
3. b. Blood backs up in esophageal vein