NSG 552 PSYCHOPHARMACOLOGY EXAM 1
PRACTICE QUESTIONS WITH VERIFIED ANSWERS
1. Which term describes the study of what the body does to a medication?
A. Pharmacodynamics
B. Pharmacokinetics
C. Pharmacogenomics
D. Psychopharmacology
- Answers -: B. Pharmacokinetics
2. Which process is included in pharmacokinetics?
A. Receptor binding
B. Mechanism of action
C. Absorption
D. Therapeutic response
- Answers -: C. Absorption
3. Pharmacodynamics primarily describes:
A. How a drug is excreted
B. How the body metabolizes a drug
C. What a drug does to the body
D. How rapidly a drug is absorbed
- Answers -: C. What a drug does to the body
4. Which sequence correctly represents ADME?
A. Absorption, distribution, metabolism, excretion
B. Activation, distribution, metabolism, elimination
C. Absorption, degradation, metabolism, elimination
D. Activation, digestion, metabolism, excretion
- Answers -: A. Absorption, distribution, metabolism, excretion
5. A medication that binds to a receptor and produces a biological response is called a:
A. Antagonist
B. Agonist
C. Enzyme inhibitor
,D. Transporter
- Answers -: B. Agonist
6. A medication that binds to a receptor but blocks activation by another ligand is a(n):
A. Agonist
B. Partial agonist
C. Antagonist
D. Enzyme inducer
- Answers -: C. Antagonist
7. A partial agonist produces:
A. No receptor activity
B. A response that is less than that of a full agonist
C. Complete receptor blockade
D. Irreversible receptor destruction
- Answers -: B. A response that is less than that of a full agonist
8. Which factor can significantly alter medication response between two patients
receiving the same dose?
A. Pharmacogenetic differences
B. Tablet color
C. Prescription handwriting
D. Medication packaging
- Answers -: A. Pharmacogenetic differences
9. The therapeutic index is primarily used to describe:
A. Medication absorption
B. The relationship between therapeutic and toxic doses
C. Drug half-life only
D. Receptor affinity only
- Answers -: B. The relationship between therapeutic and toxic doses
10. A medication with a narrow therapeutic index requires:
A. No laboratory monitoring
B. Careful monitoring of drug levels and clinical response
C. Automatic dose doubling
, D. Administration only at bedtime
- Answers -: B. Careful monitoring of drug levels and clinical response
11. Bioavailability refers to:
A. The amount of medication eliminated in urine
B. The fraction of administered drug reaching systemic circulation
C. The drug's receptor affinity
D. The medication's half-life
- Answers -: B. The fraction of administered drug reaching systemic circulation
12. First-pass metabolism most significantly affects medications administered:
A. Intravenously
B. Orally
C. Intramuscularly
D. Transdermally
- Answers -: B. Orally
13. The cytochrome P450 system is particularly important in:
A. Drug metabolism
B. Neurotransmitter storage
C. Red blood cell production
D. Glucose absorption
- Answers -: A. Drug metabolism
14. A CYP450 enzyme inhibitor may cause a substrate medication to:
A. Have a lower serum concentration
B. Be metabolized more rapidly
C. Have an increased serum concentration
D. Become completely inactive immediately
- Answers -: C. Have an increased serum concentration
15. A CYP450 enzyme inducer generally causes substrate medications to be:
A. Metabolized more rapidly
B. Metabolized more slowly
C. Completely absorbed
D. Converted into antagonists
PRACTICE QUESTIONS WITH VERIFIED ANSWERS
1. Which term describes the study of what the body does to a medication?
A. Pharmacodynamics
B. Pharmacokinetics
C. Pharmacogenomics
D. Psychopharmacology
- Answers -: B. Pharmacokinetics
2. Which process is included in pharmacokinetics?
A. Receptor binding
B. Mechanism of action
C. Absorption
D. Therapeutic response
- Answers -: C. Absorption
3. Pharmacodynamics primarily describes:
A. How a drug is excreted
B. How the body metabolizes a drug
C. What a drug does to the body
D. How rapidly a drug is absorbed
- Answers -: C. What a drug does to the body
4. Which sequence correctly represents ADME?
A. Absorption, distribution, metabolism, excretion
B. Activation, distribution, metabolism, elimination
C. Absorption, degradation, metabolism, elimination
D. Activation, digestion, metabolism, excretion
- Answers -: A. Absorption, distribution, metabolism, excretion
5. A medication that binds to a receptor and produces a biological response is called a:
A. Antagonist
B. Agonist
C. Enzyme inhibitor
,D. Transporter
- Answers -: B. Agonist
6. A medication that binds to a receptor but blocks activation by another ligand is a(n):
A. Agonist
B. Partial agonist
C. Antagonist
D. Enzyme inducer
- Answers -: C. Antagonist
7. A partial agonist produces:
A. No receptor activity
B. A response that is less than that of a full agonist
C. Complete receptor blockade
D. Irreversible receptor destruction
- Answers -: B. A response that is less than that of a full agonist
8. Which factor can significantly alter medication response between two patients
receiving the same dose?
A. Pharmacogenetic differences
B. Tablet color
C. Prescription handwriting
D. Medication packaging
- Answers -: A. Pharmacogenetic differences
9. The therapeutic index is primarily used to describe:
A. Medication absorption
B. The relationship between therapeutic and toxic doses
C. Drug half-life only
D. Receptor affinity only
- Answers -: B. The relationship between therapeutic and toxic doses
10. A medication with a narrow therapeutic index requires:
A. No laboratory monitoring
B. Careful monitoring of drug levels and clinical response
C. Automatic dose doubling
, D. Administration only at bedtime
- Answers -: B. Careful monitoring of drug levels and clinical response
11. Bioavailability refers to:
A. The amount of medication eliminated in urine
B. The fraction of administered drug reaching systemic circulation
C. The drug's receptor affinity
D. The medication's half-life
- Answers -: B. The fraction of administered drug reaching systemic circulation
12. First-pass metabolism most significantly affects medications administered:
A. Intravenously
B. Orally
C. Intramuscularly
D. Transdermally
- Answers -: B. Orally
13. The cytochrome P450 system is particularly important in:
A. Drug metabolism
B. Neurotransmitter storage
C. Red blood cell production
D. Glucose absorption
- Answers -: A. Drug metabolism
14. A CYP450 enzyme inhibitor may cause a substrate medication to:
A. Have a lower serum concentration
B. Be metabolized more rapidly
C. Have an increased serum concentration
D. Become completely inactive immediately
- Answers -: C. Have an increased serum concentration
15. A CYP450 enzyme inducer generally causes substrate medications to be:
A. Metabolized more rapidly
B. Metabolized more slowly
C. Completely absorbed
D. Converted into antagonists
