NSG 5003 Chapter 6, Epigenetics and
Disease
What genetic process is likely responsible for the occurrence of asthma in only one of a
pair
of identical twins?
a. Epigenetic modifications c. Transgenerational inheritance
b. Genomic imprinting d. Methylation - answerANS: A
Prader-Willi syndrome causes a chromosomal defect that is:
a. Initiated by postnatal exposure to a virus
b. Inherited from the father
c. Related to maternal alcohol abuse
d. Transferred from mother to child - answerANS: B
A malfunction in DNA methylation can lead to:
a. Hypothyroidism c. Cancer
b. Blindness d. Diabetes mellitus - answerANS: C
Which statement is true regarding the embryonic development of stem cells?
a. They are already differentiated.
b. They are referred to as housekeeping genes.
c. They already demonstrate DNA sequencing.
d. They are said to be pluripotent. - answerANS: D
When microRNA (miRNA) are methylated their messenger RNA (mRNA) targets are
over-expressed, the resulting effect on existing cancer would be:
a. Cell death c. Remission
b. Metastasis d. Relapse - answerANS: B
The difference between DNA sequence mutations and epigenetic modifications is:
a. DNA sequence mutations can be directly altered.
b. Leukemia is a result of only DNA sequence mutation.
c. Epigenetic modifications can be reversed.
d. No known drug therapies are available for epigenetic modifications. - answerANS: C
Which term refers to the silenced gene of a gene pair?
a. Activated c. Mutated
b. Altered d. Imprinted - answerANS: D
The shape of the face of a child diagnosed with Russell-Silver syndrome is likely to be:
a. Round c. Triangular
Disease
What genetic process is likely responsible for the occurrence of asthma in only one of a
pair
of identical twins?
a. Epigenetic modifications c. Transgenerational inheritance
b. Genomic imprinting d. Methylation - answerANS: A
Prader-Willi syndrome causes a chromosomal defect that is:
a. Initiated by postnatal exposure to a virus
b. Inherited from the father
c. Related to maternal alcohol abuse
d. Transferred from mother to child - answerANS: B
A malfunction in DNA methylation can lead to:
a. Hypothyroidism c. Cancer
b. Blindness d. Diabetes mellitus - answerANS: C
Which statement is true regarding the embryonic development of stem cells?
a. They are already differentiated.
b. They are referred to as housekeeping genes.
c. They already demonstrate DNA sequencing.
d. They are said to be pluripotent. - answerANS: D
When microRNA (miRNA) are methylated their messenger RNA (mRNA) targets are
over-expressed, the resulting effect on existing cancer would be:
a. Cell death c. Remission
b. Metastasis d. Relapse - answerANS: B
The difference between DNA sequence mutations and epigenetic modifications is:
a. DNA sequence mutations can be directly altered.
b. Leukemia is a result of only DNA sequence mutation.
c. Epigenetic modifications can be reversed.
d. No known drug therapies are available for epigenetic modifications. - answerANS: C
Which term refers to the silenced gene of a gene pair?
a. Activated c. Mutated
b. Altered d. Imprinted - answerANS: D
The shape of the face of a child diagnosed with Russell-Silver syndrome is likely to be:
a. Round c. Triangular
